HsaINT0133011 @ hg19
Intron Retention
Gene
ENSG00000188086 | PRSS45
Description
protease, serine, 45 [Source:HGNC Symbol;Acc:30717]
Coordinates
chr3:46784403-46785630:-
Coord C1 exon
chr3:46785461-46785630
Coord A exon
chr3:46784573-46785460
Coord C2 exon
chr3:46784403-46784572
Length
888 bp
Sequences
Splice sites
5' ss Seq
TCAGTGAGT
5' ss Score
7.68
3' ss Seq
GTCACTGCTCACCCTGCTAGGCT
3' ss Score
6.36
Exon sequences
Seq C1 exon
CACCAAAGAGTACTCAGTGGTGCTTGGCACCTCCAAGCTGCAGCCCATGAACTTCAGCAGGGCCCTCTGGGTCCCTGTGAGGGACATCATTATGCACCCCAAGTACTGGGGCCGGGCCTTCATCATGGGTGACGTTGCCCTTGTCCACCTTCAAACACCTGTCACCTTCA
Seq A exon
GTGAGTACGTGCAGCCCATCTGCCTCCCGGAGCCCAATTTCAACCTGAAGGTTGGGACGCAGTGTTGGGTGACTGGCTGGAGCCAGGTTAAGCAGCGCTTTTCAGATGAGCAGGATGGGATGGGGGGTGGGTGCAGTACCACCGAGAGCACACTCCTTTCCTTCTGGGGCCTTTCCTGCTGGACCTGGTTCTCTGAATGTGTTGACCACTCCTCATGTGGTGACCATTGTCACTGTTTATGTGGACACCTCATTCAGGCCTGGTAGTGCCTGGGCTGGGCATGACCATCTGTGTCTTATAGAAGCTCAGAGCTGGGCATTCACTCATTCCTTCACTTGACACACTTTGAGTGTCGGCACCCAGCCCTTGGGATTAGAAATGCATGCCCTGCCTGGAGGGAAGTCATGATTGGGTGTGGGTGTGGGCACAGGCTGAGGAGAACAAGGCAAAGTTCTTGTCTGGTGGTCTTGAGATCCAGCTGGGAGGGATCTGGAATGAGCTCTGGGCAGAGGGACTGCCTTGAGGCCCTGGAGGAGGAGCGAGTGTTAACGAAGGTGGGGAGAGCGGCCGTGCCAGCAGAGCTGAGAGTCTGCAGGGAAGCAGCGCGGGGCTGGGCCCCAGATTGGAAGCGGCTGCACTGAGACTTGAGTTATGGCTGGTTTGGTTCAGAAGCAGAAGTTTCCCAAGAAGGGGATCTGGACTCAGAGCCTTCGAGGGCGGGGGCTTTTCAGACAAGGCCTGCACTGCAGGGGGAGGGGCCGGTGAAGGAGGGGAGGGCTTGGAGGTATGACAGGCGGTGGCTGGGCTGAGTCTCCAGGGTGAAGGGGACAGGACCCTGGACAGAGGTCAGGGTTGGGTGGAGTGAGAGGTCACTGCTCACCCTGCTAG
Seq C2 exon
GCTCCACAGCCAACTCCATGCTGACCCCAGAGCTGCAGGAGGCTGAGGTGTTTATCATGGACAACAAGAGGTGTGACCGGCATTACAAGAAGTCCTTCTTCCCCCCAGTTGTCCCCCTTGTCCTGGGGGACATGATCTGTGCCACCAATTATGGGGAAAACTTGTGCTAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000188086-PRSS45:NM_199183:2
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
No protein impact description available
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.033
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=FE(54.3=100)
A:
NA
C2:
PF0008921=Trypsin=PD(9.5=17.5),PF0008921=Trypsin=PU(53.5=94.7)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACCAAAGAGTACTCAGTGGTGC
R:
GCACAAGTTTTCCCCATAATTGGT
Band lengths:
336-1224
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)