HsaINT0134077 @ hg38
Intron Retention
Gene
ENSG00000073756 | PTGS2
Description
prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605]
Coordinates
chr1:186675249-186676184:-
Coord C1 exon
chr1:186675898-186676184
Coord A exon
chr1:186675397-186675897
Coord C2 exon
chr1:186675249-186675396
Length
501 bp
Sequences
Splice sites
5' ss Seq
AGGGTAAGC
5' ss Score
9.04
3' ss Seq
ACTAATTTTACTTTCCACAGGTT
3' ss Score
9
Exon sequences
Seq C1 exon
GAGAGACTATTAAGATTGTGATTGAAGATTATGTGCAACACTTGAGTGGCTATCACTTCAAACTGAAATTTGACCCAGAACTACTTTTCAACAAACAATTCCAGTACCAAAATCGTATTGCTGCTGAATTTAACACCCTCTATCACTGGCATCCCCTTCTGCCTGACACCTTTCAAATTCATGACCAGAAATACAACTATCAACAGTTTATCTACAACAACTCTATATTGCTGGAACATGGAATTACCCAGTTTGTTGAATCATTCACCAGGCAAATTGCTGGCAGG
Seq A exon
GTAAGCATTATTATTGAAAACCAAAACAAAAGACTAGTCAGTAACTTTAGAATTTCTGCCACGGAAATTATTTTTCTTAAACTTACTAAAAGAGTAGTTAGTTATATTGCTAGTAAAATTATTTTATTGATATAAGAAGCCTAACTTTGTTTGAAAAGTCTAAACTTTTAGTCTAGTCTACAGTTGTCAGACAAATAGCAAATTGTACCCCTACCTTAAAAATATTTTCAAAAAGTATCTATAATCTTATAGGAATAAATATTTTAGGCTTGAATACTAGTGTTATTTTTGAAATGTAAAAAGGCAAATTAGTTCTAGGCTGGTGTCCCATTGAATTTTAAGCAGAGCTCCTGTTGAAATGTAGGTAAGCATCTTTCCAGCAAATAAAAATTGTCTCCGCTGGGAGTTTCAGTTTTACCTGATTTGTACCTAAGGCAAGCTGAATACAAACAGTAAATATGCCTAAAATTCTTGTTTTACAACTAATTTTACTTTCCACAG
Seq C2 exon
GTTGCTGGTGGTAGGAATGTTCCACCCGCAGTACAGAAAGTATCACAGGCTTCCATTGACCAGAGCAGGCAGATGAAATACCAGTCTTTTAATGAGTACCGCAAACGCTTTATGCTGAAGCCCTATGAATCATTTGAAGAACTTACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000073756:ENST00000367468:8
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0309810=An_peroxidase=FE(21.4=100)
A:
NA
C2:
PF0309810=An_peroxidase=FE(11.0=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGAAGATTATGTGCAACACTTGAGT
R:
TTCATCTGCCTGCTCTGGTCA
Band lengths:
342-843
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development