HsaINT0137039 @ hg19
Intron Retention
Gene
ENSG00000116191 | RALGPS2
Description
Ral GEF with PH domain and SH3 binding motif 2 [Source:HGNC Symbol;Acc:30279]
Coordinates
chr1:178854211-178855255:+
Coord C1 exon
chr1:178854211-178854346
Coord A exon
chr1:178854347-178855103
Coord C2 exon
chr1:178855104-178855255
Length
757 bp
Sequences
Splice sites
5' ss Seq
TAAGTCAGC
5' ss Score
-3.84
3' ss Seq
ACTTTTTTTTCTGTTTCTAGTTT
3' ss Score
9.97
Exon sequences
Seq C1 exon
GTCCTGAAGTAGGAGCGTCTCCACAGAGTGGACGAAAAAGTGTGGCAGCTGAAGGAGCCTTGCTCCCACAGACACCGCCATCCCCTCGGAATCTGATTCCACATGGACATAGGAAGTGCCATAGTTTGGGTTATAA
Seq A exon
GTCAGCATTTTTAATTTTATCTTTCAAATTTTTAAGTCTTTTGTAATTGGATTTATTGTCGATTTATTAGTTCAGTAGAAAATGGTATCCTTGAATAGTTTTCTTTTTTCTTAATAGCTGTTTTCTGATTCAGTAAAATGCCTTGTTTGCCTAAAAGCTTTTATTTCTTACTTTACCTGAATTTGGAAATGGGATTTTGTCAACAATGCATTTATATTTGGGGACGATAAATGAACATTACAGAGGGCCATCATAAATAAAATCAGGATAGCAATATACCTTTTTAAAAGAGTTACAACCTTTATATCAAGACAGTCATTGTTTGTCTTAACCAAAATAAGTCAAAAATAACAGCTATAAAAATTATTTTCTTTATTCCTAAATATAAAGAAAACTGACTTTTTGTTTAACTTCATTAGTTTTGCAGTATTGTTTTTTCAAAATGGGGACACATGTTCACTTTTGCCATGATTTCTCTGGAAATGTAATAACTGTTCTCCAAAAGTGAATGTGGAAACAATTTTTTAAACGGACACGAGGCTTAAAATGAAATTATTTTAAAGTATGCTCTAATTATATAGATAGATAGGGCCAGGTTTCCTAAAACATTTTCCCTAAACTGTTCATTTGAGGCTTTTATGGTAAGATCTGAGTATGACAGTTAGGTAAATCTTTTATGTCCTAAATCTTTATATAAAGAGCAGTTTTTAAATTAGTAACAATAATAAAAGATATGAACTTTTTTTTCTGTTTCTAG
Seq C2 exon
TTTCATTCATAAAATGAACACAGCAGAATTTAAGAGTGCAACGTTTCCAAATGCAGGACCAAGACATCTGTTAGATGATAGCGTCATGGAGCCCCATGCGCCATCTCGAGGCCAAGCTGAAAGTTCTACTCTTTCTAGTGGAATATCAATAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000116191-RALGPS2:NM_152663:12
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.762 A=NA C2=0.737
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Other Inclusion Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGCGTCTCCACAGAGTG
R:
AGTAGAACTTTCAGCTTGGCCT
Band lengths:
254-1011
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)