HsaINT0137392 @ hg38
Intron Retention
Gene
ENSG00000091428 | RAPGEF4
Description
Rap guanine nucleotide exchange factor 4 [Source:HGNC Symbol;Acc:HGNC:16626]
Coordinates
chr2:172990810-172996554:+
Coord C1 exon
chr2:172990810-172990925
Coord A exon
chr2:172990926-172996465
Coord C2 exon
chr2:172996466-172996554
Length
5540 bp
Sequences
Splice sites
5' ss Seq
AAAGTATGT
5' ss Score
6.93
3' ss Seq
CATTTTTGTTTCTTATCCAGGTA
3' ss Score
9.97
Exon sequences
Seq C1 exon
GACGTGGAGGCGAATACAGTCAGACTTAAAGAACATGACCAAGATGTCTTGGTGCTGGAGAAGGTCCCAGCAGGGAACAGAGCTTCTAATCAAGGAAACTCACAGCCTCAGCAAAA
Seq A exon
GTATGTTTGCATCCAACACTGTAATTGCCAGACTATGATTAACCTTTTCACATGGTATCATCATTTCTACAATAGCATGTTCTCCTTTTTTGTGGAAGATGGCAGTGTATGTGACTTTTTTCCTCTCTATTGACTAATCACACATCTTGTGGAGTATAATGTATCCATTTCTGGCACAGCATTGAGCCGGGTGCTGCCTAGAGTAATTCGGGAGAGAATATTCCTTTACTCTAAAAACCACTCTTTGTATACAGTGTTCAACTGTAATAGCTGTGGAACAGAAGGCGTGTGAGAGAACAATGGGAATAGCAATGCCAGGCAGCTCAAAGGATATGAAGGCCCCTGGGTGATGAGAACTTTTGGTATTTGAATTTCGTATGCAGGATTTCGCGTGAAGTGTTTTCCTCTTGTTATCAGAATGAGCGTCTTTGATGGAAACCCAGACTTCCAATATAAAACAGTCTATTGATTTCAGCCCAGAAGCATCCATTTGGCCTCATTCATACTTTCCTGCTAATGTCAAAAGGCCATTAGCTTCACATTTCTCAGATGTCCTGTTTAACTTGAGTCTTTTTCAGCATACCGATGTTCAGTTCCAGCTTTTGCTGCAACTTACTACATAAGACTGCATCAAATGTACCAACATTTGAGTGGTAAGACAGAATAGAAAATGTGGCTCTAAGAAATTACAGAAAATTGCAGAATCTAGTTTTTAAAATGGAGATTAATTTTCAATCTTAGTGTAATAAAAACACCAATTCTGTAGCTAAAGAAATGTTGCCCAATAATATGTTGAAGGAGAATGCATCTCAAGTAATTTTCCTTTGTTTGCCAAATAAGCAAGATGTTTCCTTTATCAAGGCATTCACCATAAATGATTAATTTTTATTGTTTAGACTAAAAGTCTAAGGCCCAGACATTTTCATTTGGGTGAATCAACATATTTGCAAAGAGGGCAGGAAAAAAGATAATATTATTAAATAGCCATAGTATATTTTGCAGATTTTATAGGATTCTTATCATATTACAACACCTTTTAAAAGATGGAGAAATTTATGCTCAGAGCCACAAGTTACTTGCCCAAGGTCTCAAAGCTTGTAATGGCAGAGCTTGGATTCAAGTCCAGCTTGACCAGTTTTCACATGCCTATCCCCCTTCCACCTGACAGCTTACTATAACAAAATATAGTAGATAAGACTACATACTCAACACTGTTTAGTAAATATTGCAAACCACTCCATATCGAAAGAACTGACATCAAAAGGACTATGTAAAAAAACTACCTGTCACTTACAAAACTATAAAATTACCATAGAAATTTCCTTATTATTTATTGTTTTCTACTGTCTGTTCTTGAAATTGTTCTTGCCCAAATGTTTTTAACAGTTTTCCTTCCAGTCCACTAAGGAGGATAAGAATGAAAACATTTTTTTAATGTGAAGGTTGGGACTGCTTCTAGTGATTTTCTTTGGTTCCCTTAAATACCTGGTGTTTTATCTGTATTTTAAACTAATGCTTCAGATGTCTGGGGAAAATTATGCTTACTGAAAAGGCAAGCCTTGAGAATTCTCCTTAACCTAGAAACATCTGATCAAGAGGTTCCCTGGAGGTCCCCTTGCTTGACTTCTTCATGTCATTGGGGAATGATCAAAAGCATTTGCCTGTTACAATGGCTTTCATTCAGGGTGTTCTCCAAATATAGGTTTCTTATGAAATCAAACTAAAAGGAATGGAAAAGAAGAGACCGTATGTTTTATTATTTTAGGCCTGATCTGATTTTCTATTATATCTCCTTATTTGTGTCCTGTATTCCAATCCAAATTTCTTCCGCAATTCAAAAACTTATGCATGTTCACAATGAGCCATTTAAGAAATATCAGTGAGTACAAATTAATGTACCACACATAATCATTTCCCTGAAGAATGAAAAGCTGCTCTCTCAAGGGGTCATTTTCCATGTTGAGCTTTCCCAAATGAGACCAGAGTTGAAGGGGAGGGGGGCATGTAGATAAATATGGGGCTGATATTCCGGACTTCAAAAATGTGGCATCAACCATGTGTATGGATGGACTTAAAATTTAGGAAGCTGTAGGGCCTCTCCTCAGAAATTATCCTTTTTGAGCTCAAAAAGGGTCACCATGTTGGTGCTGCTAATAATGTTATTTTTCTGGTTCATTTTTTTCCCTGAAAAATCCAGAATAGTTTATGTGCACATTTTTAACTTTCAAAACCTCCTGACTCTACCTAAGCATCTCAACTCTGAGTGTGATATTAAAAATGTCAATAATAAGACAATATTTGCCATGAAGGATAAATTCCATGGAGCCCTTAGTCGTTTACTGTTTCGCATGTCTTTCTGCTGTGTGGTTATGCGGGTTTAGTAAGAAAGAATTTGAAATGCATATTCCTGTTTTCGTTACTGTGTTGCTTTTATCTTAGACTGTTTTCTCATTGCTCAACTCCATCCTGTGTGCAGGAAGACAGTCTCTTTCAGGTCCCCTTCTCCACACCCTTCTCTATTCTAGGAACAGATTGTAGTGTCCTCATTTGCAGAAAAATATTTTATGTCAGAGGTTTAAAACTTCATAGCTTATATAATGTAACCAATTGGAGTTTGCTTTTAACTTGGACTAGAGTCGCTCTTTCATGAAATAAACTGAAAAGGGTCATGCTGTGTGGTCTTCAAGTGGTCCTGACCTCATTTTAAACAGAGGCCAAGCAGTAGGTGCCTGGCAGTGGACAGTGGGAAACAAAGCCGTCACGTGATGTTTCAGCCAAACCCAGAACCCCAAGAACCCAGAGGGCTGTGTCTGGCCAGAAGTTCCTGGCCCCTCCATCTTGGAGTCCCCCACCCTAAGGGAATGTTAGCACCTAATAGCCTTCTGTGGAGCTGTGAAGAGAAGCTGGGGTAAGGTGGCCACAGCAACTGTACCACGAGAGGAAGTCTTTGGTAGCAAAAGAAAGATCCTGGGGGTCTCCGACTGGCCAGGTGGGCAGAGCTTAGAGAGGCCACTTTCTAGAGAGGTGATCAGGCATCTGGCTTGCCTCTCAGATCTCTATTACTTTTGACCAGCCATAATGCCCTAGCTAAAGGATGTCCAAACAAAGAATACCAGAATGTGAAGCCAACCTTCTAGTAGAATTAAACTTTTGACAAGGGGACACATTTTACAAACTGATGTATGAGTCACACGGCTAGCTATAGAGCTTGCAACTTCCCAGCAGCCTGGTGCCACGCGAAGTAACAGACTGGTTTTCCCCCCATTCAGTTTTCATGTTATGGAATGTACATATACTCCTATTGAAATAAAACTCGTTTTCAGAAACAAACTGAACAAGCCCTCTTTAGAGGAAGGTTGTTAATTACATGGAGAATTTCCTGTTCTGAAAAAGCTCCAGGTAGCTAGACCTGGTCTCCATGTGGAGCGTCTTGCTGTACAAGCAGAAAAGTGCCATGAAACTCATGCTTGTTCTCTGAAGCCAGACACACCTGGCTCATGTCAGAGGTCTCCCATTTACTAACTCTGTGACCTGAGGCATGATGCCTCCCCGTCCTGAGCGGTCTCTCCATCTGCAGAATGAAGATAATATTTAACTAGCAGGAGTAAACAGGACGACCTTATTCAGTGCCCACCTAGCTGTCTAGGGCATAGTAAACATTCGACAGATGTTGCTCTCTCTAACCCCGTTTCCTGATTAATGTGGCCAACGCTACTCTTCTTCCAGCTCATCTGGTGAGTGCTATCAAAGAATCATATATTTCAGGAATTACTGAATTAATTGAGCAATATTCTCTATTTCAATATCGAAAGTCATTTATAAATATGCCCTCTTCTTTCCTCAAATATGCATTGCCCACAAGAGGAAAAACCATTGTCTTCTACCTTATCTCTTTTGAGAAAGGGGTCAGACTTTTGAGATGAAAGTAGACTATTTTTTTTTTCTATTCCCCTTCTCTCCTCCTCTAGGCTCCAAAGCCAGGTTTCCTCAAAGACTTAACTGTTTAGCTTCCTTTTGGTCTTGTGCGCGCACTATAGTTTTAGCTAACAGCTGCCTTCCAGATAGACTGCATTGGCCACCTCATTCAATACCAGAGGTGCTCCCCTCACCATTTTCACATGCACATATGTTAAAATGTCTGCACATCACTCCCTCAGGCCATGGGTTAAGATCCTGAGATTTAACAATATGTTAAGAGTTACTCTTGGGATCTCAACACACCTCAAAAGTCTCAAACAGGCAAGGAAACCAGAGCTGAATTCTCACTGCTTTCTGAACATTAGACAATTTTATTTTCATTGTTGTTTTTACTTGCCTGTTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTGTATTTTGAGATGGAGTCTTGCTGTCACCCAGGCAGGAGTGCAGTGGTGTGATCTCCGCTCACTGCAGCCTCCGCCTCCCGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCTAACTAGCTGGGACTACAGGCATGTGCCACCACGCCCAGCTAATTTTTTGTATTTTAGTAGAGACGGGGCTTCACCGTGTTGCCCAGGCTGGTTGCGAACTTCTGAGCTCAGGCAATCCGCCCGCCTCGGCCTCCCAAAGTGCTAGGATTACAGACGTGAGCCACTGCGCCTGGCCCCTACTTGCCTGTTATTTTTAAGTGAAATTCCAAGCAGAAAAGCAAAGCCTGAGTTTTGGAAGAGAAGCACTCAGATCATCTGAATGTATTTTGTCTACAGCTCCCACATAGTAGTGTTTTGTCACTGTCTTGAGTATGATTTTGAAACAGTTCACATGCAACTTAAAAAATAAATCCTCCTGTGTTAATTGAAGAACACCATGGAAAGATCTTCTGAAATAATGTCTAATATAACCCCCAGTAATTTATATCTGGCATTGAAATAAATTATAAGGATTTTCTACTGCTGATTTATTTCCCATTCATGATCTACTGGGGTTTGTTTGTTTGCTCATCAGTGTTATGGGGTTTTGTTTGCTTTCTCTCGTTTTATTATTAGCTGAATTTCCAAAGCACATACCAGTGTACAGTTGGGAAAGACAGAGCATTCCAGAAATAGGCGGGGGAATCCAGTGTGGGAAGAAGTTTTGCTATGAGTAACCCATATATGGATAACCTAGCTTACTCTCACTTCCCCTCACCAGCTCCCCCTGCCTGACCTGAACTGCCCTGGGTTTTACATGTTCCTTTTTATTCTCCTTTGGAAAAAAGACTGAAGTTTCTCAGTTCCCAGCCTGCTAAAGCTGCTCTTCAAGAAGTTTACCTTATTTCCATATAGGGAAAAAAGAACAGTGTTTGTAGTAACGACTTCACTTTGTGGGTTTTCTGTTTGTTTGTTTTGTCTTCTTGTGTGACTTTGACAAAGTGTGTGGTCTCTCTTACCATGAAAGGTATATGGTTCCCTGGGATCTCAAATTAAAAAAAAAAAAAACTTAGATAAGTAAAAGTTTTTTTAATGATTTGCCCACTTTTGAAAAATTAATGGCATTTTTGTTTCTTATCCAG
Seq C2 exon
GTATACTGTGATGTCAGGAACACCTGAAAAAATTTTAGAGCATTTTCTAGAAACAATACGCCTTGAGGCAACTTTAAATGAAGCAACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000091428:ENST00000397081:15
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.333 A=NA C2=0.161
Domain overlap (PFAM):
C1:
PF0002724=cNMP_binding=PD(2.3=5.1)
A:
NA
C2:
PF0061815=RasGEF_N=PU(26.2=90.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development