HsaINT0146211 @ hg19
Intron Retention
Gene
ENSG00000175356 | SCUBE2
Description
signal peptide, CUB domain, EGF-like 2 [Source:HGNC Symbol;Acc:30425]
Coordinates
chr11:9088244-9091042:-
Coord C1 exon
chr11:9090917-9091042
Coord A exon
chr11:9088361-9090916
Coord C2 exon
chr11:9088244-9088360
Length
2556 bp
Sequences
Splice sites
5' ss Seq
TCTGTAAGT
5' ss Score
7.96
3' ss Seq
TTGATTCATTTTGCTGTCAGTGA
3' ss Score
4.68
Exon sequences
Seq C1 exon
AGGGCCTGAGCTGCATGAATAAGGATCACGGCTGTAGTCACATCTGCAAGGAGGCCCCAAGGGGCAGCGTCGCCTGTGAGTGCAGGCCTGGTTTTGAGCTGGCCAAGAACCAGAGAGACTGCATCT
Seq A exon
GTAAGTATGGGCCAGTGCACACCTGCCATGGGAACCGTCGTATTCCACAGGCTGCCTTCTGTGGCCCAGCTCAGAAGCACCACCTCATGGCACGGCTGCAGCAGCAGGGAAGGCAGTTAGCACGGGATACCGACCTCTACCAAGTACTTGTTCACTGCAGAAGGGTGGTCTCCCTTAGGGAAGGGAAATGATATTTTAAAAAGGAACTCATCAGGAGGAAATGAAATTCAGGAGTAAGGAGTGTGAATGTTGGGGGGCAGTTCTCCCTGTTCCCACAGAATAAAACCAAATGTCCTCATCTGGCAATCACAGCTCTTTGCCACCAGGTCCTGCTTCCCCTATAAACCTCATCTGCCTCCTTTCCGCAGACACTACTCCCCTTGCCTTTGGAGAACAGCCCAAATCCTTTGATGCCTCCAGGCCTTTCCCAAGCCCTCCTGCCTTCCTGGCGTGGTGGACTCTCACTCAACCTTCAATATTCTGTTTAACTTCTAATAAGGATAAGCATAATAGCTACCTTTTGGTGGGGAATTTATTTTGTGCAAAGGCTTGTCTCAAGATGTGCCATATCCCATTTAATTCTTACAAGCACTGCACTGTGAGCTCAGTATTATTACACTCATTTTCAGTTGTCGAAGTTGTGCAGAAGGTGAAGCAACAAGGTCACACAGGGAGTGAGTGGCAAATGAGTGTTCAAACCCTGGTCTGTTGAGCTCTAAAGCTGTGCTCTTAATCCCATGCTACCATCCTCTGCTATCAGAAGCCTCCTGGGTGCTTCAGACAGGGCAGCCATCTTGTACTTTGGCTCCCACAGCACTTTCCTCAGCTGTATAGCTCTGGGTTGACTTGTGTGTTGATGTGTCTGTCTCCCCAGGTATGAGCCCCCTCCAAGTCAGGGACCTTGCCTCATTTTTCCTCTCAGTCCTCCCCTGGTACCTGCTATGGGATATGCTCAGTACACTTGTGTTTAATGAGTGGGTAAATGGGTGGCCTACACCATCGGGCCGCAGCTCCTGCACCACGATTGTAGTAACAAAACTCCACCTGGGAACAGGAAACCACTGGCAATTCATGGTGTTCCTAAACCACGATTTATGCCAGGGGAAGCACTGAGGAGTTCCCTTTAGGAACCTTCCCAAAGCCATGGACAGAAGACCCCTGCCATTTGGTGGGGATGGTGGTTTATGGTGAGTAGGAGATGAGGGGACAGTTTCACTGGTGAGGGACTTCTCTCCATTGTCTCCCTCACAAAGCAGACTGCCACCCCAAAGCTGTCCAAGCCAAGGCTGGTGCCACCATCACACTCAAGCAACAGGTTCTGACATGCTCTTAGGGCCCCTCGAAGTCAGGCTGTCCCTGAGGGCTTCCAGTGAGCTAGCAGAGTGGAGACCATTTTCCCACCTCCAGATCTTCGGAAGGAAGACCCAGACCCTCCAAGACTCACCTGCGGGGCGAGACCCTCAACATTTCATAGTCTTTCAGGGAACAGTTGCTGAAGGGGGCGGGGGGGTGGGCACCTGTAAGCTTGTTTTTAAAGATTTTAAATGTCTTTAAGATATCACTGCTCAAATAATATTGTTCTGTTATTAACTTTTTTTAATTTTAACATTAACATATTTTAACATTAACATTATTAACATTTTTAACATTATAACATTTTTAACATTAACATATTTAACGTTTGAGGAATTAACAAAGAAAAAAACTAAGACCTAGAATCTCACCACATAACCAGCTGTTTCAATTTTTCCATATTCCTATTTAGTTGTTGTTCATATGCATACACAATTTTTACACAGCTATAATCACAGGACAACACAAATATGTAATTAGTTCTTTTGAATTAGAAAAATTACAAAGGGCCTATGTAAAATGCAAACACTCCAAAGCATATAAAGAAAACATGCAGTTTCCCGCCTCCCGTTTCCCTTGCCAGAGGTAACCACGGTTAGCAGTTTGATGAATAGATAGTTTTGTAGTTGGCTTTTTTTCTTTTTGGCCTATCATCAATACATTCATATATAGTCTTGATAATTACCAGTTACTGTCACGTTAATTGTGTGCAGAATCATCCTGTGATTATCCTTCCTTCTAACTAATCTAGATTGAATCTGATGAGAGAAATTCTGACATATATGTACAAATTAAATATTGTCTGTTTTATTCCAGCATAAAGTGCTATAGCATTTCCCAAAGCCCCAGTACAGCTGTATTAATAGGTAAACTTCTCTAGATAGAACAAAGCAGTAGTCTAGAATCTCTTGGTATAATCTCCCTTATATAATAAAAGTCTCTCCCCCAACTCTCCCATCTCCCTCTTCCTGTATGACTTTGTTTAAACCCATGTTTCAGCATTTCTACAATTTGTATTGTAACTATCTGCATACACAGACACCACAGGGTCTGACTTGGAGTTATGTCTTTCGTGCACCATGCCTGGCATGCACTAGGTGCTCAAATACTTGCAGAATGAAAATCAGAATTTCTCTGGAGCAAACACAGCCCTGTGTTTGTGGAAATCTCAGTGCTTTATGTATTGATTCATTTTGCTGTCAG
Seq C2 exon
TGACCTGTAACCATGGGAACGGTGGGTGCCAGCACTCCTGTGACGATACAGCCGATGGCCCAGAGTGCAGCTGCCATCCACAGTACAAGATGCACACAGATGGGAGGAGCTGCCTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000175356-SCUBE2:NM_020974:5
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF146701=FXa_inhibition=WD(100=86.0)
A:
NA
C2:
PF146701=FXa_inhibition=WD(100=90.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)