HsaINT0149199 @ hg19
Intron Retention
Gene
ENSG00000095370 | SH2D3C
Description
SH2 domain containing 3C [Source:HGNC Symbol;Acc:16884]
Coordinates
chr9:130506843-130509550:-
Coord C1 exon
chr9:130509426-130509550
Coord A exon
chr9:130507379-130509425
Coord C2 exon
chr9:130506843-130507378
Length
2047 bp
Sequences
Splice sites
5' ss Seq
CTGGTATGG
5' ss Score
7.13
3' ss Seq
CTCTCTCTACCTTTCTGCAGTAA
3' ss Score
8.32
Exon sequences
Seq C1 exon
TACGTCGCTGCCCCGCCCTCGGGACTCCATCCGCAGCTGTGCCCTCAGCATGGACCAGATCCCAGACCTGCACTCACCCATGTCGCCCATCTCCGAGAGCCCTAGCTCCCCTGCCTACAGCACTG
Seq A exon
GTATGGCCAGCAGAGGGGGTGGAGCAGGTGGAGGGAATCTGTTGTTGAAGACTTCTGTCACCTATGTGTGGTTATGTGTGTTTCCGCCTCTTTTATGAGGCGCGACCTTTACCAAGAGAAAGAACTGACACTGGAATCCTGCTAACAGAACTGTTGATATCAACATATAAGATGTATCCATGGTTTGTTTATTTAGCAACTATTTATTTGTTTTTGTGACAGTTTTGCTCTTGTGGGCTGGAGTGCAGTGGTGGGATCTTGGCTCACTGCAACCTCCGCCTCCTGGGTTCAAGCGATTCTCTTGCTTCAGCCTCCCAAGTAGCTGGGATTACAGACCCCTGCCACCACGCCTGGCTAATTTTTGTATTTTTAGTAGAGACGGTGTTTCGTCATGTTGGCCAGAGTGGTCTCGAACTCCTGACCTCAGGTGATCCACCTGCCTTGGCCTCCCACAGTGCTGGGATTACAGGCGTGTGCCACCATGCCTAGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGGTGGTCTCGAACTCCTGACCTCAGGTGATCCACCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACTGCACCTGGCCTCTATTTTTCTTAATAGACTTTATTTTTTAGAGCAGTTTTAGGTTTGCAGCAAAATTAAGTGGAAAGTACGGAACACTGTGCTTTCTTATAAATACGAAGAAAGTTTCTCTGTTAGAAACATTCCAATAGATCATTTCTGGAAAAAAAATAAAAAGAATGTTTTCAACAGGCCGTATTGTCCACGTGGCAGGCCAAGTGTCACGAGAGGGGGCTGACTCAGGAGGAACTTTCGCCTAGGGTGGCATTCCATTGAAGTGTTGCTGTCTGTATCGGTTGTCACAAATCCTTCCCTAAACACAGAGCCACCAACTTTGTCATAACTACAAACTTGATTTCAAAGCAATACCCTGAGTATAAAACCTAAAATTCCTTGCCAGAATGACTTATTGGACAGTTTCTAAGCAATCTGGTATAGTAAAGCAGCCCAGATGTCAAGACTTAAATCTCAGCTGTACCACTTGCTGGCTGGGTGACCTTGGGCAGGTTAGTGCACCTCTCTGAGCTTCACTTTTCTCATCTGTAGAATGAGGATTATAAAAGTACTTACTTCATAGGACATTGAAAGGATTAAATAGACTGAGGTACAAAGAAGGGTCTTGCAGGCACTAAGAGCTTAGTAAATATCGCCTTTGAGGTTTGATGATGGTTTTACTGTCATTATGTCTCCAGCATGTTGCCAGCTCCTAGCACACAAGGTTTAGCAACAAATCATTATTGCTAATTCAGGCCGGGCATGGTGGGGCACATCTGTAATCCCAGCTACTCAGGAGGCTGAGGCACAAGAATTGCTTGAACCTGGGAGGCGGGGGTTGCAGTGAGCTGAGATCATGCCATTGCACTCCAGCCTAGGCAACAGAGCGAGACTCTGACTCAAAAAAAAGTTAGCCAGGCGTTGTGGCACATGACTGTAATCCCAGCTACTCGGGAGGCTGAGGCTCAAGAATTGAAGAATTGCTTGAACCCAGGAGGTGGAGGTTGCAGTGAGCCTAGATGGCACCACTGCACTCCAGCCTGGGCCACAGAGCGAGACAGTGACTCAAAAAAAAAAAAAAAAAAAAAAAAAAGGAAATCATTATTGCTAATTCGTCGAGAAACAATCACATGTGGCACAAGAAACTCCAGCAGGTACTCAGCTTCCCCGGATCACTGAAGCTCCTCCAAGCAGTGGGTCCCCAAGGCTGCAGCAGCCTCAGGGTGGGGCCATGCAAACTCCTGGGTCCTGGTGATTTCAGAGCATCACCTGGGCTGGTCAGCTTGCCAGAGTCAATCGGCCCTGGTCTCTGGTGATGCAGGGAGGTGGGGACATCACCTCTGTACTCCCTACAAGGAGTGAGGGAGCCTGTTCTTTGGGAAGGGGTGCGGGAATCTCACTTTGGTGGGGAGCTGCTATAACGGGGCCTCTCTCTCTACCTTTCTGCAG
Seq C2 exon
TAACCCGTGTCCATGCCGCCCCTGCAGCCCCTTCTGCCACAGCATTGCCTGCCTCCCCTGTCGCCCGCCGTTCCAGTGAGCCCCAGCTGTGTCCCGGAAGTGCCCCAAAGACCCATGGGGAGTCAGACAAGGGCCCCCACACCAGCCCCTCCCACACCCTTGGCAAGGCCTCCCCGTCACCATCACTCAGCAGCTACAGTGACCCGGACTCTGGCCACTACTGCCAGCTCCAGCCTCCCGTGCGTGGCAGCCGAGAGTGGGCAGCGACTGAGACCTCCAGCCAGCAGGCCAGGAGCTATGGGGAGAGGCTAAAGGAACTGTCAGAAAATGGGGCCCCTGAAGGGGACTGGGGCAAGACCTTCACAGTCCCCATCGTGGAAGTCACTTCTTCCTTCAACCCGGCCACCTTCCAGTCACTACTGATCCCCAGGGATAACCGGCCACTGGAGGTGGGCCTTCTGCGCAAGGTCAAGGAGCTGCTGGCAGAAGTGGATGCCCGGACGCTGGCCCGGCATGTCACCAAGGTGGACTGCCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000095370-SH2D3C:NM_001142531:5
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=1.000 A=NA C2=0.649
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0061714=RasGEF=PU(11.3=9.5)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)