HsaINT0161385 @ hg19
Intron Retention
Gene
ENSG00000136854 | STXBP1
Description
syntaxin binding protein 1 [Source:HGNC Symbol;Acc:11444]
Coordinates
chr9:130432177-130434395:+
Coord C1 exon
chr9:130432177-130432237
Coord A exon
chr9:130432238-130434329
Coord C2 exon
chr9:130434330-130434395
Length
2092 bp
Sequences
Splice sites
5' ss Seq
AAGGTAAAC
5' ss Score
8.14
3' ss Seq
TGCTTTCCTTTCCCTTACAGACC
3' ss Score
12.56
Exon sequences
Seq C1 exon
GGAAGTCACCCGGTCTCTGAAAGATTTTTCTTCTAGCAAGAGAATGAATACTGGAGAGAAG
Seq A exon
GTAAACCCATGCCAGTGCTCAAATGCCCAGTAAATTAGTCCCTGCTTTCTCTCTAAGAGCAGGGAAGCTGCCTCCTCCAAACAGGACTAGTGGGTTAGCAAGGCCATATCCCTCTCTTAGTTTATATCATTTTGCCTTATTTTTATTTTGCTTTTATTATTATTATTATTATTTTGACAGAGTCTCGCTCTTTTTCCCAGGCTGAGGTGCAGTGACAGGATCTTGGCTTACTGCAACCTCCGCATTTTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTAGAGGCACGCGCCACCACCCCTGGCTAATTTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATCTTGGCCAGGCTGGTTTTGTACTCCTGACCTCCAGCTATCCACCCACCTTGGCCTCCCAAAGTGCTAGGATTACAGGCATGAGCCACCGTGCCCGGCCATTTTTACATTTAAGATACAGATCCAGGCCGGGCATGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAAGTGGATCACAAGGTCAGGAGTTCGAGACCACCCTTGTCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAAATTATCTTGGTGTGGTAGTGGGCACCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCGGGAGGTGGAGATTGCAGTGAGGCAAGACCATGCCATTGCACTCCAGCCTGGGTGACAGAGTCAGACTCTGTCTAAAACAAACAAACAAAAAAAAGATACAGATCCAGAGCCCCTACATTTTGATATTTACAGAGAACTGCTTTTTGTTACTCTGATGGTTAATATTTACTCTTTTGGATCATGATTCATTTTAAGCCAGAAGAATGAACTGTGAGACCTTTTTTTAACTTGTGGTAAAATTATAATCTACCTTATTTATATATATAAAATTATATATATATAATTATAACCTACCTTATAGAATTTATAACCTACCTTACCTGGGCCTCTCCCTATCCTGCCTGTTTATCAGAGGTGGCACACCTGTCTTCGTCAAGGGAAGTGGAATTACCAAAATACAACTCTGGTTGTGTTACTCACTTGCTTAAAACCATTTAGGGACTTCTTGTTCCCCTTAGAATAACTCCCATCTGCAACACACACACACACACACACACACCCCCCTTCCAAAGCCCAGATCATCAGCCCCACAGGCCTCTCTCTGGTCTCATCTCTGCCCCTATCCTTGTTGCCCTGCCTCCTTGCTCCAGCCACACCAGTGTCCTCTTGCCTCAGACCTGGCCAGGTTCTTTGGCTCAGGCATCATTTCCTCAGGGAAACCCTCCCCGGGTCCCTACCCAGACTAGGCAGATGCCTGTGCCACGTGCACCCACACTACCTGGTGAGTCCCCTCGAAGGGCCCTGATCTCTGCAGTGCTTTGGCTCCTCTCCTGGATGCTCTGATTCTCCGTGAATTAGAGATTCTTTTTTTTTTTTCTTTTGTCCTTGTATCTCCAGCACCTAATAGTTCCTGGTATATAGTAGTAATTCAGTAAATTTTTGTTGGGTAAATGGATGGGATTAGATGGCCCACACAGAAAGCACACAGACCTGTCTTGCCCATTGGGTGCAGATTCCCACCCTCTGTGACCTCCCTGTGCTCCTCCCGTCCACGTAGCCACAGTCTTTCTGCCAGGAGGAAGTGCAAACTTGATGCTAAGGCTGCTTGAGCTGAGGATGAAGAAAAGCAGTGAATAGAAGGATTTTTTTTCCTCAGCAAGAATTAGCTCTCAACAGCTTTCTAGTCCAATAAGCATAGAATAAAATATAACTGCTAGACTTCAGAGTTCAGTTCCCAACCTATAAGACAATCATATTTGGATCAAAAAAAATTTTGAGCCAGAGGCCTGGAAATCTAAACACACATGATTTTGTGTTTCACAGATTCATTTTGAGTGTTACAGAGTGTGCGCTTGGGAACCCTAGTGTGGGCAGCTGTCCTGTCCTGTGCCCACTAGCCTTGCAAAGCCTCCTAACATCAGGGCCATTAGAGTGACACCATGTGCTTTCCTTTCCCTTACAG
Seq C2 exon
ACCACCATGCGGGACCTGTCCCAGATGCTGAAGAAGATGCCTCAGTACCAGAAAGAGCTCAGCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000136854-STXBP1:NM_003165:11
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.571 A=NA C2=0.182
Domain overlap (PFAM):
C1:
PF0099518=Sec1=FE(3.6=100),PF140711=YlbD_coat=FE(20.0=100)
A:
NA
C2:
PF0099518=Sec1=FE(3.8=100),PF140711=YlbD_coat=FE(21.0=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)