HsaINT0161396 @ hg19
Intron Retention
Gene
ENSG00000136854 | STXBP1
Description
syntaxin binding protein 1 [Source:HGNC Symbol;Acc:11444]
Coordinates
chr9:130420654-130422387:+
Coord C1 exon
chr9:130420654-130420730
Coord A exon
chr9:130420731-130422308
Coord C2 exon
chr9:130422309-130422387
Length
1578 bp
Sequences
Splice sites
5' ss Seq
AAGGTAAAC
5' ss Score
8.14
3' ss Seq
TTTTTCCCCCCCATCCACAGTCC
3' ss Score
10.28
Exon sequences
Seq C1 exon
TTGTGGAAGATATCAATAAGCGCAGAGAGCCGCTCCCCAGCCTGGAGGCTGTGTATCTCATCACTCCATCCGAGAAG
Seq A exon
GTAAACCTTCCACCAGAGGAGGACTCTGGCTAAGGTTAGATGGACTGGCTTGGGATTTATGTGGCACAGACTGTCTGACATTGCTAGGTTAAGCACGCATTTAACACACTGCTCTGTTTAAGCATGCAATCCACAATGGGGTGGGGTCGGGGGTGGTGTTTATGCAGTGAGAAGTGATGAATGTATTAAGCGTTCTTAAACACAGCAGCTGTGCAGAAAACCAGAGCCTGTGTTCCGTGGCCCTGGATCATTCTAGTTTTCCCCCTTGCACTCCCTCTTCAGGTAGGACCCACTCTGTCTAATTAGCAGTCCACCTCCAGACTTTGGTATTTTATGCTTTCATTTTATTTTATCAATATCCAGTTACTGTTCACATTTACCTGTCTTATAATTTTGGAGGTTACTTCAAATCACTATCCAAACAAGGTCCAACTCCTTGCTTCTGGGTAATAGTTGTCTTAGGCATGTTTTCTTTTGTTTTGTTTTGTTGGTTTTGTTTTGTTTTTTGAGACGAAGTCTAGCTCTGTTGCCCAGGCTGGAGTGCAGTGGCACGATCTCGGCTCAGTGCAACCTCTGCCTCCCAGGTTCAAGAGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCACCCCCCCGCCACACCCAGCTAATTTTTGTATTTTTGGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAAGTGATCTACCTGTCTTGGTCTCCCAAAGTGCTGGGATTACAAGCATGAGCCACCACTCTCAGCCTTTTTTGTTTTTTTGGGTTGTTGTTGTTGTTTTTTGTTTGTTTGTTTTTGTTTTTGTTTTTTTTTGTTTTTTTTTTGAGACAGGTCTCTCTCCATCACCCAGGCTGGAGTGCAGTGTTGTGATCACAGTTCACTACAGCCCCGACCTCCGGGGCTTAAGTGATCCTCCCACCTCAGCCTCCCAAACAGCTGGGACTACAGGCACATGCCACCATGCCCAGCTAATTTTTGGTAGAGATGGAGATCTTGCTATGTTGCCCAGGCTAGTGGCAAACTCCTGAGCTCAAGTGATCCACCTGCCTTGGCCTCCCAAAGTGTTGGGATTACAGTTGTGAGCCACCATGCCAGCCTTAGGTGTCTTAGTCTATATAAATTTCCTCCAATTTTCACACTTTTTTTTTTCACTTTGAAAACTGGCTTACATATGAATTTCTACAGATGCAATTAAATTGCCAAAAGGTCATCAATATGAATCTCCTGGAAGGTTTCTGCCGGGTTTCCTTTTTTGTGGGTGTCTTCCTAACAACTAATTACAGTGGCTCCAAAGAACTGATACTGTCATTCCAGAATGAGCTAAGAAGGCCTTTGTTCATCTAAACTCTGAAATAGTACTAATTTTAAGTCCTCAGGACTTGGTTATGGCCAAACATGAGTGTTAGAATTATGCATCAAAAATCCCCTGATTTTGTGCAAGTGGCTTGAAGCCATTGGATTTAACTCAGTTCAGATACAGGTCCCATTTGGCTCTAGAATTGGATTCAGGTCCCTCTTTTTCCCCCCCATCCACAG
Seq C2 exon
TCCGTCCACTCTCTCATCAGTGACTTTAAGGACCCGCCGACTGCTAAATACCGGGCTGCACACGTCTTCTTCACTGACT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000136854-STXBP1:NM_003165:4
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF148471=Ras_bdg_2=FE(26.9=100),PF0099518=Sec1=FE(37.3=100)
A:
NA
C2:
PF148471=Ras_bdg_2=PD(9.7=33.3),PF0099518=Sec1=PD(6.0=14.8)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)