HsaINT0169747 @ hg19
Intron Retention
Gene
ENSG00000187045 | TMPRSS6
Description
transmembrane protease, serine 6 [Source:HGNC Symbol;Acc:16517]
Coordinates
chr22:37471175-37480444:-
Coord C1 exon
chr22:37480335-37480444
Coord A exon
chr22:37471321-37480334
Coord C2 exon
chr22:37471175-37471320
Length
9014 bp
Sequences
Splice sites
5' ss Seq
GAGGTACCA
5' ss Score
6.43
3' ss Seq
TCGTCTCTGACTCCCCCCAGGCT
3' ss Score
9.05
Exon sequences
Seq C1 exon
GTGCCCTCTCTGGACTACGGCTTGGCCCTCTGGTTTGATGCCTATGCACTGAGGAGGCAGAAGTATGATTTGCCGTGCACCCAGGGCCAGTGGACGATCCAGAACAGGAG
Seq A exon
GTACCACTTCCTCTCCTCCCTCTGGCTTCCTTTCCTCCCTCCCCCTCCCTCTCTTCCCTCCTCAATAGTGACCCCCTCATTGGAAGCCCAAGTCCCCAATCTCAGAGGGGCAGCAAGGGGAGCGAGCAGAGGCTGGGGCTGGTGTCAGGCCTGTTGCCCTTGACCTTGTCCTCGTCCCAGCCTCCGCCCTGGCCCCGGCTTCCCCTCTGGCTACCCCAGAGGTCTCAGACACGTTTGGTCATCAGACACCTTGGATGTTTATTCTAATTACAGCAAAATTGTCTCATCTTCTTGGGTGCTGTAACCCCCTCTGGCACCCTCAATCCTTCAATAAAATGTTTCCAGAGCCAAAGGACTCATGGGCACTTTGGTGCCTTCCCTCTAAACCCAAGGCGTACCATCAGAGGTGCCTCTCCCTTATCACGAACCCCTGCTGCACAGCCAGGCCCAATCCCATTGCACAGGGTAACATGGAAATCATGGGTGCCCTGGATCCCCCGAATCCCCAACGGGGCACTTGCCCTCTTCCCTGCTCTTGCCCTTGCTCCCTCTGGTAACTAAGTTTCCGACAAAGAAGTGAGTCCTTACAGAGATGTGAGCAAGAGACAGTGGGGTTAGGCTAAGCGACTACCGTTGCCAGGGTCACTATGGCATGAGGCCAGTAGGTGCCCACTGGGCCTGGCCACCAGGAAGCCATGGGTGGTGCCGACAGCTTCAGAGGCCTGGGCTGGGCAAGGAGGCAGGGAAACAGAGACAGGGTGTATGGACAGGTTTTCATTTGTCTGGGAAGAAAAGAGAACTAGGAAATTCAAGGAAGGGGACATTTAAGACGGGAGAGGTTCCATATCTCAAATGTGTGGATCATCCCAGCATCCCCAGAGGGAGAGAAGGAGGCTCAGGTGCAGGTAATATTGTTTAGAGTGGGGAGGGTGGGCAAGGGGAGAGGGAGGCCCTCCCATGGCTCCATTGTTGGGGAGCAGAGGTTTGGGGAGAGAGAAGAGGAATATTGAAGCAGCGATGGCAGAGCCAGGGAGACCCTTTCCCTGGGAATCCGGGGTGAAAACGGTCATCGTGTCAGCGTCAGGAAAGAGGAGACTCTATCCTTCATCGCAGGTTGGGCCTCTGCCCTCCCTTCCAACCTCGGAATTCTGGGGGCCTAATGGGTTCAGAGTCTAGTATGAAAGATTTGTCATTTCTTGATTTCACAGAGTTTGAATATCTAAGATGCCAGTCTTGGAAGATGCCAAAATTGGAAGGCTCTGGGGCTCTAGAATTCTTGGATTTCTGGGGTGTGTGTTCCCAATCACCAACACTTGTAATTTGCTTGTTGGCTGATCCTATTCAAAAGGATCATCCAGACAAAAGGTGACGAAGAATGACAAGGTTTGCTTGACTCCTTTTTGCAATTTATCTGGGACTAGGATTAAAAGAAAGGAGAAGAAATACTCATGGCATGATCTAGGGCTATGCTGTTGGGGGTAACATGGGGAGTGACTTTGGGCCTGTGCTGTTGGGGGTGATATGGCGAAGCAGTGCCTTCAGGGCTTTGCATTTGGTGGTGATATGCTGATGGAGTGTGACATCAGGCCTGTGCTGCTGGGGTGACATGCTGGTTCAGTGATGTCAGGCCTGTGCTGTCTGGAGAGCAGAAGGCTTCTGTAGCATGATGGGGGCACCTCTGGGAACGGCTGCCCTGACCCCTCATGGAGCTCACTTGAAGCCTCCTTGCTACTCACCTAGGCTGGGGATGGCTGGCTTCACCCCCGCTCACAGGAACCCGCAGGGTGACCCTGAGATGGATCCATGATTCACAGTTCTGCGAATGATGAGAACATGTTTTCCTGCCTCCCTCCCTACCGCAGAGCTGAACTTTATGTCTCAGGGAGGCCCACAAAGGAGAAGGAACAGTCTTGGGTCTGACACTCCCTGTCTCATCCCTCACCCCCTTGGCGACTCCATTTGCCAGAGGCGGGGCCCCAGCATTCAGGGGTTGTGGGGGGTTCGGTGGCCTGGAGTTAGGTGCTAAGACAGGCGTTCAGTGCATTGGCCCAACAACTTGTGTGGTCATTGGCGCCGTTCCTGTTTCCCAGAGAAGGAAATCAAGGCTCAGCAGGATTAGGTGGCACGCAGATGGGTCCACAGATGGGGTCTCTCCCATACCCCCAACAGCCACAAACAGCAGGCCAAAGGATGCTCCACCCCATGCTTCCTGTGGGAAGGCCCTCCTCCCTCCCTGATGCAGTTGGGCAAGGGTCTGGGTACTGGGGAGACAGGGACTTCGTGAGCTACCCTTGGGTAATGACAGAGAGAGTGTGGAACACGGATGGGAGAGTCTTTTCCCTAATCCAAAGGAATGATGCCTTGATGGTGAATTTGAGGCACTAGGACAGCTTCCAACAGGGTGGAGGGATCTCGCCAGAGTCTGAGCACCACTGAGCTATAGAATGTGTGGGCTGAACTGGTCCTAGCACCCAACCTATGGTACAGGTGGGGAAACTGGGACCAGCGAGGGCTAAGGACTTGGCCTCTTGTCCCTGTCTTTTCTGCCTTTCAGTGGTGGAGATGGGCTTCAGGGTGTAGCCAAGCGGTGGCTGGGTGGTGAGGATGAGGCCTGACAGCTCCCTGTGCCCCCATAGCTCCCCCTCTCTCTGTTCAGTCCTCCCTCGCCACACGGGGGTGGAAGTGCTCAGCAGGGGCTGGCATCAGGGTTTGCATGGATCCCTAGATGCACCCCCTTCCTTGTCTGTGAAACGAGGGGTTCAGGCCAGCCCAGGGCCCCAATCTTTGATTGCTTACCCATCAGGAAGCTATTGTCTCCCATACAAGTTGTGTTTATTAATTCCTGGCCAAACGCCATTCCAAGTCAGGCTGGTGAGGTGGAAAGCGCTTAAGTGTCGAAGCCAGACAGGCCAGGGCTCAGCACCTGTCTCCTCTGCTTCCTACCTGGGCGAGGACTTACATCTCCCAACCTCAGGTAACTCATCTGAAAAAAGGGCGTGAAAGAGACCCCCACCCTGGGAAGACTAAGTGAGACAACGCGTGGAGAACATTGCACACGCGGGCTTAGGTCAAGTGCAACAAACCTGCGTTCATCACCGGCTCTCACTCTGCTCTGGGCAGGCACAAGCTGAGGGGTTTATGGTGCTGGCTCTTTCAGCCTCAACAACCCAGCGAGGAAGCAGGTGCCTGTACTGCCTTCACAGACCAGTGAGACACCCAAGACACAGAGAGATGAAGTAATTTGCACAAAGTCACCCAGCTCTTTGAGCCAGAGTTAAGGCCAGGCAGCCTGATCTGGAGTGCACGTGGGTGCACAGATGCATGTCTGTGTGCGTGCGTACATCCATGCATGTCTGTGCACGTGTACGTGCATGTGTGTGTGGTCCACGTGTGCGATTCTTCCCTCTGAGCCTCTAGCGGCCCATGCCAGCTGGTGACTCCCTCAGCCAAGGCATCCCCAGCCAACCCACTGGCATCTGGGTGGGGGGATCGACAGTTTCTGTGGCTGTCCCACCAGTTCCAGAGCGGCCTGGGAAGTCCCAGCCCTTTCTTCTCAGACTTTCATTAAGGGTCCAGGGTCCCCAGGGGCAGACTCTTGTCCCCTCCCCGCAGACTCCTCCTGTGTGAATGAATGTGGAAGGGAAGGCAGAGGTGGCGCCTGCAAACCATCCGCACTGGGCCACTGTGCCCTCTAGTTATGATCATGGGCGATAGTGATCATCCCATGTAGATGCTGAGAAATTCTTAGAATGAGCATTTGTTGGAAATCTGCTTGTGTGGGTGGCAAAGACATGAGAGGTCTAGGGAAGAGCAGATTTTCAGACAAGGCACTTTAGGGAGGGGGAGGTACAGCCCTTTGGCCCAGAATGCCCATTGATGGAGAGGGCGGGTCAGGGGAGAGGGTATCTTAACCCTCAAGTGCCAGCGTAGTGATGAGGAAAGGCTGGCCTGGTGGGCCCCCCATGGACTAAGCATCCTTAGGCACTTCACCTGACTCCTCTGAGACTGTGGTGCCTCCTTCACCCCTGACCTGCCTGCTTTCTACCTAGCTTCTCCCGGTGCCCACTTGAGCCCAGCTGAGGCCTCAGGCCCTTGAGTGGCCTGGGGGTGGTAGAGGGACTTGGCCCGTGAGATCTGGCCATGGCTGCTCCATTTCGCAGAAGCCACTCTCACGGGCTGCCACCGAAGCACGGGCTTCCCCCTTTCCGGGAACCTGCCTCCTGCCAGCTTCCTCTCCTGTGACATCACTTCTCTTGTGATTCGCCCCACCATTTCCACTCACTCCCAGCCAGTGGGGACAGGCAGAACCATGGGTTCCCTAGGCCAGCTGGAGCCACCCCCGACCCGGCCTGGCCTGGCTATGGGGTGGCCCTTGTGTTCTCCGGAGCGCTAGTGGCCAGCACAGGCGGCAGCCACAGACACTTAGTAGGAACTTCAGTGTGGCTGACCTGAGCTGGGCTGGCCGTGCAGGAGAGTGCAAGCTGCTTCCTCCATGAGCTCACAGCCTGACGTCAGCAAGTGCTTCAAAGAAGTCATTTCCTATGCATGCCTTAAACCATGCCACAAGGGAGATACGATCACCCCTGTTTTACAAATGTGAAAACTAAAGCTTGCTGAGGGTGACCCAAGGTCACACAGCTTGTTCCTGGGGCAAAGCCAGGCTGCCAATTCAGCTCTGCAGCCCCAGGTCTAGAGCTCTGGCAATGCCAGGTGCTGCTCTCCTCCCCTCTTCAGCACTTGCCTTCTGTGACCCTCCTTCCCCTTTAATCTGTCTGTAGGTAAGGGCACGGGGGTGTGCATTCATCCACCCACGCACCCTTCTTTCCTTCTTCCTTCTTGTGTTCTCCCCACCCTTCCATCCATCCATCCATCCATCCATGCATCTATCCCTCCAGGCAGTACATCCTGACAGGGTCCCTGTCTACCTCCTGGATGAGGCAAGAAGGAAATATTCCCCATATCCAGAGAGGTGAGGAAGCAAGGCAGGCCACACGGTGCAAAAATGTGCCTTCAGACACTCAGTACTTTGTAGCCAAGATGAACTGGCAGGCATCGCAGCAGTCAGGCTTCTGGTGCTTCTTGGAGAGGGCTAGAGGGGAGCACTTGTTGGACGGGAGGCACTGGAGAGCCAGAGAATGTGCACCCTCCCCCAGAGAGTTCTGCAGCAGAAACAGAAAACTCAGATGGGCCAAGGGGCCAGGCCAGGGCTAGAGTCTATGATGGGGGGTAGGGTAGTCCAGTGGTGTTTTCGGGGCTTTTCTTTCTTTCTCTCTTTCTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTTTCTTTCTTTCTTTCTCTTTTTCTCCTTCTCCTTCTCCTTCTTCCTCTTCTTTCTCTTTCTTCTTTCTTCTTCCTTATTCTCCTTTTCCCTTCTTCTCCCTTCCTCTTCTCCTTCTTCTCCTTCTCTTCCTTCTCCTCCTCCTCTTTCTTCTTCTTCTCCTTCTCCTCTTCCTCCTCCTCCTTCTTCTTCTCCTCCTCCTTCTCCTCATTCTCTTTCTCCTTTCTTCCTCTTCATCTTTTCTTCTTCTTCTCCTCCGCCTCCTCCTTCCTCTTCCTCTTCCTCTTCCTCTTCTCCTTCTAAAGGAGCAGGAATCTGGATTATTATGTGAAATTAGCTCGCGACTCAATGAAGCAATTTCTACATGGTGCATAAACAGATTGTCTTTACGCTGAGTGACTCCGCTTGGGCCACTAGATTTCAGCCGCTGCCTTGAATTCCTCTCTGGCGCTTTCTAAGCAGACGCTTGTTCCAGGGATTCCACCACCTCTACCCGTGCTCCAGGCCTCCAGAGTGAGAACCAAACACTGCCCAGACAGACAGGTTCCCGGGTACACGGTGAGGCCCTGGGGAAAGGTTGCTGCCAGCTACAGACTGGTTCTAGGACTCTCCCTGGAGGTTGAGAGAACTTCCTGTAGCAGGCACAGGTGTCTTTGCCTTACAGCCCCTGCCCAAGGCTTGGGTGACACTACAGGTCCTCAACGCAGTTGCTTCTAGGGTGAAACGTTCCACTCCCCTCCAACCCCGGCTTGGGTTCCTTCTCTGTCTCCCCACAATCTCCCTGTGACTGTGGGAAGGGACACCCCAAGGCCCATGGGATGCGCTTGACTCCTCATTCCCCGCACTAGTCCTTCCCAACCCCTGGCTCCCCTGTCTACTTCCTGAGGTCCTTCTGTGAGGAAAACAATCCATGATAACTTTATAGACAAACAGACACCAAAACCTGCGTTTCCTGGGTTTTACAAGAGCAAGAGGGCCAGGCTTGCTCAGGGGCGCCCCCTGGCGGTGCCTCGTCCCCCACCGGCCCTGCTGGGCTGGGGGAACCATGGTCGGGGGTGGCGGCTCCCAACCTGTTCTGCCTCAGGACCCAGTCACTCTCCGCAAAATGACTGAGTACCCTAAAGAGTTTTTGCTTATACAGGTTATAGATCTATACTTGCAGCATTAGAAATTGAAACAAAATTTTAAAATGTTTATTAATTCTTTTAATATAATTATAAGCCCATTACACATTTGAATATAAATAACATTCTATGAAAATTAGTTGCATCCTCCAAAAGTAAAAACATTTAGTGACAAGAGTGCTGTCATTTTACATTTTTGTACATTTCTTTAACAACTGGCTTCACAGACTACAGGCGGGACCTTCGAATCTGCCTCCGAGTTCAATCAGTCCCGATGTCACACATCAGTCTCTGGAAAACTCGCCTGTCACCTTATGAGAGAATGAGGGCAAAAAAGGCAAATGATATCTGAGTGTTACTATAAACATGACTTTTGGACCCCCAGGGGTCCCCTGACTGTGCTTTGAGAACTGCTGGTTGGTGTAAGGGTAAGATCGTGGTCACTGTGGCCAGATAGACTTAGGGGGGTGCCAGAGTCTAGGCCAGGCGTGTGGAGGACATGGGGCATGTAGGGGGCTCAGACCTCAGAGCTCCTGTTGCAGTGGGAATTCGGAGCCCTCCCCTCAAGCAAGCTAGGTGAGCTCTTCTGGGTCCTGAGGCAAGATTCTGGCTCCACCTTGGCTCCTGCACTCTTGAGCCTCATCTGTAAAATGGGATGAGAGCAATTCCTCCCTCCCTGGGTGGAGGTGCTGCTTGAACCTCAGAATCCCCGTGCAATGAGGCCTTGTGATGCCATAGCCAATGAGGCTCAGCCCCAGCCACACACCTGGAGATGTTAAAACAGCCTCAAAGCTCATCTTCAGCTGTTCGGTGGCTAAGGAATTGATTAACTTATTGAACGGTTAAGTGCTTACCACATTCTAGAAGTTCTGGGGAAGTGCCTGGCCCTTGGGAATCATGGCCGGCTCCGCAGGGTGTTGGATTTGCTGTGGGATGTCCCCACTGGCCTTCAGGGGCATTCCTGATGCTCTCTGGATTTCCATCTGCTTTCTCTGCCAGGGGCATTTTCAGCTCTCCCTGCAGATTTTCAACCTGCACCCTGAGTGTGTTTCCCCCATCTGCAAAGCACTCTGATTTGCTCTGTGGAGGGCATTTCTATGAGCTGATGAAGCTGTCCCCATCTGTTCTGCAAGGGTGTCCCACCTGGGATGAAAAGGAACCCCCGGCTGCTGTGGAGGGAGGGTCCCACTGTCCTGGGGGAGTGGCTGCACCCACTCTGTGAAGTCATGCCGCTGCCCACTTGCTCTGTGGGGTGAGGTGCACCGGACTCTCTGCAGGAGGAACCCCTGGGCCCATGCCCTGGAGATGGGAGGGCTCCTACCTGTTCTCTGGTAGGAGAGAAAGACTCAGCCTCTCTGGAGATTCCCCCACCTGCTCTGTTTGAACAACGGTATCTTCTTGGTGGTGGTATGGCAGGGGTGCAGGGGCGGTGTTGTCCAGCAGGGATGTGAGGGTGCTCCCACAGCTGGGGGTGGTCCCACCCCGTGTGGCCATGCACAGAGAAGGTGCTGCCCATCAGCACTAAGCTACTGGTCATGGGAGAAGGACTGGTCCTTCCCTCAAGCCCACAGTGTCACAGGGAGGCAGGAGGGTTGGTGCCTAAATGGGGAGCACTGCTGCCCCCTCGTCCCACACCAAGCTCAAGGCAGATGACCGTGCACATCTGTGGACAGTGGGGCAGTCAAGGGCTTTTGCCTCAACTGACACATTGAAGCCTTTTGTCAGATTCAAGATCAACAGAAATAATTTTTCCTTTCTTTCTTTCTCTTTCTTTCTTTTCTTTTCTTTTTTCTTTCCCTCCCTCTCTCCCTTTCTTTCTTTCTCTTTCTCTTTCTTCTTTCTTTCTTTCTTCCTTTCTTTCTCTTTCTTTCTTTCTTTTTCCCTCCCTCCCTTCCTTCCTTCTTTCCCTCCCTCCTTCCTTCCTACCTTCTGTCTCTTTCTTTCTTTTTTTGACGTACTTTCGTTCTTATTGCCCAGGCTGGAGTGCAATGGCACGATCTCGGCTCACCGCAACCTCTGCTTCCTGGGTTCAAGCGATTCTCCTGCTTCAGCCTCCCGAGTAGCTGGGATTACAAGCATGTGCCACCATGCCTGGCTAATTTTGTATTTTTAGTAGCAACGGGGTTTCTCCATGTTGGTCAGTCTGGTCTCGAACTCCCGACTTCAGGTGATCCACCCACCTCAGCCTCCCAAAGTGCTGGGATTATAGGTGTGAGCCACTGCGCCCAGCCAATTTTTCTTGTTTTATAAGGGAGGAAGGTGAGGCTCAAAGAAGGACCCTGACTTGCTAGAACCTCACAGTTCACAGGTGACTGTGACTAGAATTGAGTTTTTTATCTGGCAGGCAATGGGGAGCCATTGAAGATTTTTGAGCAGGGCAGTGGCATAGCCAGGCTAGTTTCTAGAAGATGACTCTGGGGGTGCACTCATCTAAGGGAGAAATCAGGGCAGAGGAGGCACAGCGGGCGTGCAGCTCCCCCTGCCCCTCTGGCTGCCTGTCCTTGCTCTGTCTGTGCACGGGACCCAGGAGACCAGCCAGTGCAGCCCTGAGTCGTCTCTGACTCCCCCCAG
Seq C2 exon
GCTGTGTGGCTTGCGCATCCTGCAGCCCTACGCCGAGAGGATCCCCGTGGTGGCCACGGCCGGGATCACCATCAACTTCACCTCCCAGATCTCCCTCACCGGGCCCGGTGTGCGGGTGCACTATGGCTTGTACAACCAGTCGGACC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000187045-TMPRSS6:NM_153609:10
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.002 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0043115=CUB=PD(53.0=94.6)
A:
NA
C2:
PF0043115=CUB=PD(37.3=82.0),PF0005713=Ldl_recept_a=PU(2.9=2.0)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)