HsaINT0174190 @ hg38
Intron Retention
Gene
ENSG00000123607 | TTC21B
Description
tetratricopeptide repeat domain 21B [Source:HGNC Symbol;Acc:HGNC:25660]
Coordinates
chr2:165880679-165884018:-
Coord C1 exon
chr2:165883794-165884018
Coord A exon
chr2:165880800-165883793
Coord C2 exon
chr2:165880679-165880799
Length
2994 bp
Sequences
Splice sites
5' ss Seq
AGAGTAGGT
5' ss Score
4.84
3' ss Seq
TGTCTCCCATTTTTCTTCAGTCT
3' ss Score
8.97
Exon sequences
Seq C1 exon
AAGGAGCATATCCCAGCGCTCTTGGGAATGGCAACGGCTTATATGATCTTGAAACAGACTCCACGAGCCAGAAACCAGCTGAAGCGTATTGCGAAAATGAATTGGAATGCTATTGATGCTGAAGAGTTTGAGAAGAGTTGGCTGCTACTTGCTGATATTTACATTCAATCAGCAAAATATGACATGGCAGAAGACCTGTTAAAACGGTGCCTGCGTCATAATAGA
Seq A exon
GTAGGTGATTGAAGAGTAAAAAATAATTATTGACCTTTGTTGCATAAGCTTTCCATATAGATATTGTTGAGTGTTAGTCCATTTCCAAGGATTCCTGTGTGATTTTTGAAAATTAAATGTTTATTCTTACCACAATCAGGAAACAAGCATTAATAATAAGAAAAAAGCCATTTGTCCTTTAAAGTTTAAAAAAAAGAAAGATTTATGCAATTTCAAGTTTCAGCTGTAGTGATGCCCTACTTAACGGAAAGTGTTTTTGGAATGTCAAACGATTGCCTGTGATTATCCATCTCATCCCAGAACTAATGAAAATTGCAGAAGAACATTAATTGCGGACGTCTGTCCCTCCCATTAAGAAATACTCTTGATGAATTTACTGCAGCTGCATGTCATTTTCTCATTATTAGAATCTATTATGCATAATATATTTTGTGGGAGAAAATCTTTTCAGCTTTTAATTTCATTTGTTTAATAAAAATTCCTTATATTTAGGTATAAAATTGAATATTATAAAGTCCTTAGAATTTAAGGCTTTTTACTAACATTTTGATGTTTAATTACAAAAGATGTCATTATAACAGTTCTTTAAAGTTAAGATTTATTTTTTTGTTGAGAAATAATTGCACACAACTTAGAAATGATATTTATCTTCATATATTCATATCAATTACTTCAAAATCTTAATCACAGTAAATCTGTTTTATTCTCATTGAGCGAATTAGATTACAAATGGACCGTTTATTTTTTAAAGAGGAATTGTGATTATCTAGTACTATTAAGATACTTTCCTAGGAACTTAAGAACCTGAAAGATCCAAGCATTTGTCAATTTATGCACTATTCTAGACGATTAGCTACATAAATTTTATGTTAAATTGGCTTTGAAAAGCCGAATGCTCATTAATAGGCTTTGAAAATCTAAACTGCTGAATAGTTTACCCTTCTATATCTAGTCTAGGATTAACCAAGATTGCATGAGAATTTCAGTGCACATACAATTTCAGTTTGCCAGAACGCTGATAACAATACATTGCATGGTTGAACATGATGGCTGCTTTAGAAGCTTCATTCAGCCCTGCTGGTTGAATATGTTGATATTGAAAGCATGATATTTAAGAACTAAAGCTTAGGAAACTTGAATTACATAATTTAAAAAATGGAAGTCATCCATATCTGGGGCAGGAAATGTACAAGACGACACTAGACTGTCTTGCCATACCAGATGATGAAGGAAGCTATCCATGATGATTAGAGTTTGTGTGAAAGATCTAGGGGCCAACTTAAAGACACCTCTAGTAGCCGAAGTTGGGATGCTTTAAGTATTGATAAGAATGATAACTGCAATATATTGAAATACATAAAATCTGTTTAAATCCATGACTTCTCGAAGATCCAAAATAGAAAAAACAAAACAAACAAAAAACCTAATTGGTAACCACTGCAGTATGCTAGTGAACTGACTGCTATTTCTAAAGCTTGCAAATAAATATCCTGCCTTTTCTGTACAGAATTGGTTAACCAAATAGTCAATGAGACGTTTCTCATCATAGACATTTTCCAGCTAATTAATGAAGAAAGACTGATAGGCTATCCCCATTTTTCAACCCTGATAAATTTATATATGGATGTAACATCACAAAAAGAGGGAGAATCAGACATTCTGTGCCTCCCAACAGAAGAACAGACATCTATGGCAGGGCTAGGGTTGGGATGAGACAAGTGAAACACTTAGTAATCAAGATAAATAATAATTTAATGCAGCTGTGCTGAGCTTTATTGGAGCCTGAATCAAAAGGGAATATGTGCATTCCTATATTCATATTTTTATGTTTTTTAAAAAATGGGTAATTGGTAATGGTTTTAATGAAAATATTACTGGTGAGATTTCTTCCATTAAAGTGAGAAAAGTAAAATGATAAGAAATTAAGTTTAGGTATAAATAAAATGTTCAGTCTTAAATGTAGTGATTTTTAATATATACTTTCAGATTTTTCAATATTTTTAAACTCATATTCTGGAAAAAAATTACAATTAAGAAATATACAAAAACATGCATCCATGTTTTTATGCCTCAGTGTGGCTTATCATAGCACTGATGTTTGAAGTAGATTCACCTCTCTCCTCCAGAATCAAAATTGAATCCAAACCTCTACATCTAATTACAACTTCCAGAAAACGTCAGTGACATAGGAATATATTATATAAACACCACAAGGATGCAGTCAATTAACCTGCGTTGTGAGAAACTCGGGGATAAATATTCTTGTTTCTATTACATTTAATTTCAAGAAAAGAGACACAGAGAGACAGACAGACATACCAGAAGGGAAACCTCTGGATCAAGAGACTAGATCAAAACATTGACCAGTTACAATGTTTGGTCCTTATTTCAGTCCTCAATCTAACAAAAACAAATTATATTGAGACAATTAAAATTTAGACAGTACTGGATATTTGGTGCTATTAAGGAGTCATTAACATTTTAGGTGTGATAAAATTGTGGTTCTGTTTAAATAACGTCTTTTTCTTTTACAGATGCACACTAACACATTTAGACTTAGTTGATACAATATCTGAGGATTTTTTCTGGTAATACAGAAGGGTAGGTTTGTGAGATAGAGGTGAAACAGTATTAGTCAAAAAATAATTATTGAAGATAAGGGTTCATGGAGTTCATTATGCTCTTATCTCTGTATTTGTATGTGTTTAAATCACTCATAATAGTGTACCTGTGCTTGTGTAAAACACAAGTGCCCTATTGTGTATTTCTGATTCTGTAAAGAAAATCCTGATTCTGCAGATATGTGATGGAGACTTGCCATCAGAATCATTTATTAAGTTCAGTAAAAAATTTGATTGCCTAGCCAAGGTTGAAAACCATTGTTTGATTTGTCATTTAAATGGGTTGATATGATTGACCTCTATAGTCACAAACATCCCATAAAATCTTAGTGATATCAAGTTTAATCTATTGATGTCTCCCATTTTTCTTCAG
Seq C2 exon
TCTTGCTGCAAAGCTTATGAATATATGGGATACATTATGGAAAAAGAGCAAGCATATACAGATGCTGCCTTGAACTATGAGATGGCATGGAAATATAGCAATCGGACAAATCCGGCAGTAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000123607:ENST00000243344:26
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.005
Domain overlap (PFAM):
C1:
PF134241=TPR_12=PU(97.4=98.7)
A:
NA
C2:
PF134241=TPR_12=PD(1.3=2.4),PF145591=TPR_19=PU(42.2=65.9)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains