HsaINT0175319 @ hg38
Intron Retention
Gene
ENSG00000188229 | TUBB4B
Description
tubulin beta 4B class IVb [Source:HGNC Symbol;Acc:HGNC:20771]
Coordinates
chr9:137241213-137241829:+
Coord C1 exon
chr9:137241213-137241417
Coord A exon
chr9:137241418-137241720
Coord C2 exon
chr9:137241721-137241829
Length
303 bp
Sequences
Splice sites
5' ss Seq
AAGGTAAGT
5' ss Score
11
3' ss Seq
CCCGCCCGCGTCCCTTGTAGTTT
3' ss Score
8.68
Exon sequences
Seq C1 exon
GTTCTGGCAGCCCATTCCGAGACTAGCGGAGGCGGGCAGGGAGGGTATATAAGCGTTGGCGGAGCGTCGGTTGTAGCACTCTGCGCGCCCGCTCTTCTGCTGCTGTTTGTCTACTTCCTCCTGCTTCCCCGCCGCCGCCGCCGCCATCATGAGGGAAATCGTGCACTTGCAGGCCGGGCAGTGCGGCAACCAAATCGGCGCCAAG
Seq A exon
GTAAGTTGCCGGGGCGCTGGGGCCAGGCGGGCCTGCCGGGCGGTGTGGGCGGGCGGCCGGGGAAGATGGCGGCAGCAGCGGCCGGGCGGCGCCCCCGCATTGCGGCCGCCGGGCCCCCTCCGCGGGGAATTGGCCGAGCCGGGCGACCGAAGCCCCCAGGAACCCGGCGGCCAGGGCGCGCGGGGCGGGGGAGGGGCGGGGAGGGCCGGGCTGCCGCGCCCGTCCGGGGCGGGGCTGCCTCCCTGCGCACCGGCCGCGGTGACTCAGCCCCGGCCCGCCCGGGCCCGCCCGCGTCCCTTGTAG
Seq C2 exon
TTTTGGGAGGTGATCAGCGATGAGCACGGCATCGACCCCACGGGCACCTACCACGGGGACAGCGACCTGCAGCTGGAACGCATCAACGTGTACTACAATGAGGCCACCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000188229:ENST00000340384:1
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.135
Domain overlap (PFAM):
C1:
PF0009120=Tubulin=PU(7.2=84.2)
A:
NA
C2:
PF0009120=Tubulin=FE(16.2=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTTCTGGCAGCCCATTCCG
R:
GGTGGCCTCATTGTAGTACACG
Band lengths:
313-616
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains