HsaINT0177870 @ hg19
Intron Retention
Gene
ENSG00000107731 | UNC5B
Description
unc-5 homolog B (C. elegans) [Source:HGNC Symbol;Acc:12568]
Coordinates
chr10:73045083-73046626:+
Coord C1 exon
chr10:73045083-73045186
Coord A exon
chr10:73045187-73046445
Coord C2 exon
chr10:73046446-73046626
Length
1259 bp
Sequences
Splice sites
5' ss Seq
GAGGTGAGC
5' ss Score
8.7
3' ss Seq
CCTCACCCCCACTCTTGCAGGTG
3' ss Score
9.65
Exon sequences
Seq C1 exon
ACCTGCGCAAGAACTTCGATCAGGAGCCTCTGGGCAAGGAGGTGCCCCTGGACCATGAGGTTCTCCTGCAGTGCCGCCCGCCGGAGGGGGTGCCTGTGGCCGAG
Seq A exon
GTGAGCGGGGACGTAGGGACCACTGAGCACGGCCCTGTGGCCATGCCTGCAGAAGCCAGGCAGGCATGGTATTTACCACCAGCCATGGTGCTAGTCTCCCAGAGCCCTGCCCCTTTCGCAGATGAGATCGAGGCTTAGCACAGAGAAGAGAACTGTTACCTCTGTCGAACGCAGCAATGCCAGATCCCAGCTGGGTCTGCCACAGGCATAACCCCACGGGATGGGGTGGCTAAGGCAGAAATCCCCAGAACTCAGGGGCTCCTTAGGTAGACCTCCAGCTCAGTCTCTATCTCCTGCCCCACCCAGAACCCAAGGCCCCAGCTTTCTGGATGCGAAAGGATCCCATCATGCGTGTGTGTGAGTGTGTTCTCCCCCACGAGCTGATCACCCCTTCCTGAAACCACAGTCTTTGGATTGCTGTCCTCTCTCGCCATCCTTACCTATGTTCCAGACATACTCCCTGCACTGGTGGTCCAGGGATTAGAGCTGCATCTCAGCTTTGCCCAGCAGAGTGGACGGCTGGGGCAGTCAGGACCCTGACTTCCAGCCTGGGATCAGCCCTCTCTGATCCCAAAACCATGCACTCATCATTCAGCCTCTCCCAGCCCAAACCCTCCTCTGCGTAGTGGGCTCAGACAAATACCCCTGGCCCATATATGCTAGGCACTTAGCACGCTGGTCTCTGCAACAACCCTGCAAAGTGGATGTTACCATTCCATCCCACAGCAAGGAAGCAGGGCTGGGAGGGGCCCAGTGGCCACCTAGGGTGAGGCAGCTGGTGAGTGGCAGAGCTGGGGTTTGGACCCAGGTCTGCCAGACCCGGGGACCTTCTTCGTATCACCTCCCAGGCTTTTCTTCCTGGCTAGCAGAGCTGGGAGGAGTTAATGATGAAGACAGATACTCCTGGCTAGCACCTATTTAGTTAGTTTAACTCAACTTCCTCTGAGCATTGTTCTCGGCACCTTACACATGCTAACTCATGTAATCCTCGCGATGGATCCCTATGGGGTAGGTGCTATTCAATTCCATCTTGCAGTTGATGAAATTGAGTCCCTGAGTGGTAAGTCCCCTCCCAAGACCACCCAGCTGGCAAATGGTGCTCTTAACCCCAGAGCTGTACAGTGTCCAGTGCTATAGTCCCACCAAGGCCCTGCCTCACTGCCACGACTATGGCGTGGACCCAGGTAGAACTGCCCTTCTTCTGTTTATGATCAAACCTGTCCTGGGCCCTCACTGCCCCCTCACCCCCACTCTTGCAG
Seq C2 exon
GTGGAATGGCTCAAGAATGAGGATGTCATCGACCCCACCCAGGACACCAACTTCCTGCTCACCATCGACCACAACCTCATCATCCGCCAGGCCCGCCTGTCGGACACTGCCAACTATACCTGCGTGGCCAAGAACATCGTGGCCAAACGCCGGAGCACCACTGCCACCGTCATCGTCTACG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000107731-UNC5B:NM_170744:4
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0767911=I-set=PU(34.1=88.6)
A:
NA
C2:
PF0767911=I-set=PD(63.7=95.1)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCGCAAGAACTTCGATCAGGA
R:
TAGACGATGACGGTGGCAGT
Band lengths:
279-1538
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)