HsaINT0179931 @ hg38
Intron Retention
Gene
ENSG00000160293 | VAV2
Description
vav guanine nucleotide exchange factor 2 [Source:HGNC Symbol;Acc:HGNC:12658]
Coordinates
chr9:133791783-133795736:-
Coord C1 exon
chr9:133795668-133795736
Coord A exon
chr9:133791870-133795667
Coord C2 exon
chr9:133791783-133791869
Length
3798 bp
Sequences
Splice sites
5' ss Seq
CAGGTGTGT
5' ss Score
6.99
3' ss Seq
CTCTGCCTCTTGTTTTCAAGGAC
3' ss Score
9.71
Exon sequences
Seq C1 exon
GAGCTTCTGAGCCATTCTGCGGAACGGCCTGAGAGGCAGCAGCTCAAAGAAGCACTGGAAGCCATGCAG
Seq A exon
GTGTGTGGGTAAACTGAGGCAGGGGAGAAGCCACCGTCTGGCTTAGCCCGTGTTCTTGGACTGGAATTGGGCTCATTAACGAGCCTCAGTTTTGACTGTGGACAGTTTCCTGGGACAGCAGGAGTTGGGGCAGGGCAGGGCAGGGCAGTGGGTGAGACCCACAGGAGGTAGAGGTGACGGGTGGAGGGCACTGCAGGTCAGGTGCCCCCTCAGGTGTCCCGAGTCCTAACCTCACCTGTCCAACAAGACCTCCCTTGAGCCTCCCCTCCCCCTGCTTTTCCCCCAGGCATTGGCCTCCATTCTGGGCTTTCTGGCCCAGTGCTTCTCACTCCCAGCACTGAGGCTTCTGCTTCTAAAATGCCACCTCCGGTGCCATCTCTCAGCTACCTGCCTGGGGAGCTCCTTCGCTCCTGGCTGTTTCGAGGGCCCCCAGCCAGCCATGCCTCCCTCTCTCCCCTTGTCCGGGTGAGCTCAGCTCATGCCACTCCCTTGCTCAGAAACCTTCCGTGGCTCCCTCTGCCCATGAAGCAGGCATGGGCTCCTCACTCTGGCACTCCCGGCCTTCTGCAGGATACTTGCCCCTGATGTCGCAGCTGTGTTCAGCACAGTTCCAGGCAGGTTTGATCCCTCCCAGGCTCCTGCACGTGCCCTGCACTTCCCCGGCTCCGGGTGTTGGCTCAGGTGCACCCTCCTCCTCGTCACCTGGCCACGTCCTGCTCATCCTGCCTTCACTGTGGACAGAACGTTTTCCAGGGAGGATCGCCCCCCACTGGGTTCTGTCCTCAGGGAACTGGCTTCCTCGTGGGTGGCACTCTTCCTCCTGGACACACTTGTTCGTGCCATCTCCTTCCCAGCCAGGCATGTGTCAGCCATAGTCACCTGTGTCCCCAGGCCAGGCACAGCACCTGGCATGTGGTAGGTCCCCTCCAGCTGCATCTGGGTGGAGGGATGACGACCCCCCCCACATCTCCCTCGTCGGGAGCACAGGACACCTCTGCCAGCCCCCCTCAGGGCTGCAGTCCTGCCCTCTGACACCTGGCCCCTGCCCTCTGGGCAGCCCCCCTGGGCTTTGGGCCCCCTTTTCCTTTCCCAGGTACCTCATTTAAGGAGCTCCCTCTGGGTGGGGGAGGGGCTGTAATCTGTCTCTGTCTATAGCTGCTGTTGGGCTGGGACGGGAGTGGGGCCAGTGCTTGGCCGCCGGTGCTAAGAGGTTCTCTGAGCAGGGCTTGTGCTCGGGGAGAAATTTACTCCAAATCCTGTGGGCACTCGTGTGTGGGCACGGGAGGTGGTCCCAGAGACCTTCAGATTCCCGCTCGGCTGCACTGGGCAGCGAGCACCCTGAGGAATGCTCCAGGAAAGCCTCCTGCCATGACGGGCTGACAGAACTTTCTCGGTGTCAGCTCTGCAGCCCCCAAGCCGCCCCTCTCCAACACCTGCTCTGGCCTGTCTGCTGTGAGCCACGGTGTGTGAGCCAGCGTGGATGCGTCCTCGGGGGCTCTGAGACAGTGACAGCAGGTGCAGTGGGCCGTGCACCCGGGCCCTGAGTGTGGTCTTGCGTTTCATACTCTCAGCACTCGGTGTCTGGCTGGCGAGTGGCTCTGAGCCCCTCGACGGGATGGTTTCCCAGGAGTGTAGCTCACGGTGCTGCACAAAGTACTCGGTGACTTGCGGGTGTGCGTCTGCCTTTCTGAGAGCCACCGAACCTCATCATGAAACTTCAGGGCTGGGGGGATTTTAGAAGTCTTTTGATCCATTCCCAATTTATATAGGAAGTCATTCATGCAGCCACTATGGGAGTCGTCGCTGTACCTGGGCTTGATTTCCCCTAGGGACTGAGGGCTCACTCCTTGTACGGCAGCGTCTTTGAGAATCAGCCCCCGTGCCGCTGTGGGCCTGAGGTTTGTCTCCAAGGGAATTGCGGTTTTAGGTCCAAGCTCCATGAGCTGACTGCAGTCCTGCCTCTGTATCAAAGTACAGACATTTCCCTCACCTGCTCATTCATTCGGGCAACTTCCATCTGTTCCTATTTCATGCCAGGCATTGGGCCAGGTGCACGCAGGGGCCGCGGTGGTCACAGTTGTAATGTTTCTGCCTTTGGGAGGGGGGTGGTCCTGAGCTCCAGACTTGCTACTGGGGTCCTTGTCTCTGGGAATTTATTCCTTATTTTAAAGGCAAGTGGACAACGACAAGAAAACGGAACACCCCTTTCAGACAGCGTGCTGCAGCCTCCCCAGGAAGTTCCCTCCTGCGGGGTGGGTGGGGAGCCAATGGTGAGGTCTTCTAGGAACGAGGAAGGGCGGGAGGGATGGGAACCTGCTGAAGACCTGGCTCTGGCTCTGGCTCTGGCCCTGGCTGGTCACTTGCATTTTGGGGAATTCCACCCGCTGCTCTCGGGGGGCAGGGCCAGGACCGCCCACGTGGCCGGCTCCCTTGGGTTCCGCTGTGGGCCAGGTCTGGACACTGCGTTTTCTGGACTGAAGTGGGCACTGCTCTCTGGTGGCCAGCACGAGGATTGCAGCACGGCAGGCAGGCGCCGGAGTGGGGGTGGCCAGACCCGTGGAGAGAGGGACTTCCTGACCCCTCATTCTGTCCAGGCTCCAAGGGGAGGCTGTGGCTTAGAGAGGCTGGGGAGGGGGAAGCTTCCCAAGAACAGGGACATAGGTCAGCCCAAGTCTAGGTGGCTCTTATGTGGCCTGATGTGGCTCCCACACACAGGGCTGCTTCCCTCTATTAGGATGTTTAAGAGGGACCACGTGATGGGGTAGAAAGAAGTGGCACCAGCCAGGAGTTTGGGGCTCTTGGCATCATCACTGACGAGGTGTGGCTCTCGGTCAGTGTGTTCCCTTTCCTGCCTCAGTTTCCTCATCTGTCATGCAGAGGTGATGTTTTTCAGCCCTCCTGTCTCGAGGGCGGCCTCCCCGGCAGGATGGAGGAAGAAGGTCCAGAAACGCCCGGTGCCTGGATGCTGGGTGGGGGGTGGGGGGGGGGGTCCCTTGGGGGCTGAGCTCCTGCATGTATGTGCGTGCATGCACACACACGCTCACACACACACACCCTGCACAGCACAGCTTGCTCACACACACAACCACACAGTCAGACACACCCCACCCGGCACAACCTGCTCACATACACACACACAATAACACACACCCAATCACACGCACCCCACTCAGCATAACCTGCTCACACAATCACACACACAATCACACACACCCTACCCAGTACAGCCCACTCAGACACACATGTTCTCACACAATCACTCATACACATACACACCACAGCACAGCCCGCTCACACACACACACACATGCACCCCACCCAGCACAGCTCACTCACACATACACACAATCACACACACATACCCCACCCAGCACAGCTCGCTCACATACCACACACCCCACCCAGTACAGCCCGCTTATACACACAGTCACACACACCCCAACCAGCACAACCAGCTCACACACACAGTCACACACACCCCACCCAGTACAGCCCGCTTACACACACACAGTCACACACACCCCACCCAGCACAACCCGCTCACACACACCCCACACAGTACAGCCCGCTCACACACACATGCTGTCTCACACACACACACCACAGCACAGTCCGCTCACACATGCTCACACACACACACCCCACCCAGCACAGCTCATTCACACACAGTCACACACCCCCCACCCAGCACAGCCCGCTCACATGCACACACACCCCACCCAGTACAGCCTGCTTACACACACAGTCACACACACCCCACCCAGCACAGCCCGCTCACCTCTGCCTCTTGTTTTCAAG
Seq C2 exon
GACTTGGCGATGTACATCAATGAAGTTAAACGGGACAAGGAGACCTTGAGGAAAATCAGCGAATTTCAGAGTTCTATAGAAAATTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000160293:ENST00000371850:12
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.068 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0062115=RhoGEF=FE(12.6=100),PF084296=PLU-1=FE(14.2=100)
A:
NA
C2:
PF0062115=RhoGEF=PD(4.0=24.1),PF084296=PLU-1=FE(18.1=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains