HsaINT0186856 @ hg19
Intron Retention
Gene
ENSG00000235109 | ZNF323
Description
zinc finger protein 323 [Source:HGNC Symbol;Acc:14097]
Coordinates
chr6:28295160-28297491:-
Coord C1 exon
chr6:28297080-28297491
Coord A exon
chr6:28295311-28297079
Coord C2 exon
chr6:28295160-28295310
Length
1769 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGA
5' ss Score
9.22
3' ss Seq
ATATGCCTACCTGCCTTCAGGCT
3' ss Score
7.95
Exon sequences
Seq C1 exon
CCAGAGTAAGCCTTCCAAATTAACCCCAGGAATGGCTTCAACAGAGGAACAGTACGATCTTAAGATTGTGAAAGTGGAGGAAGACCCTATCTGGGACCAAGAAACCCACCTTCGAGGGAACAACTTTTCTGGCCAAGAAGCCTCCCGACAACTTTTTAGGCAGTTTTGTTACCAAGAGACTCCTGGTCCCCGAGAAGCTCTGAGCCGGCTCCGAGAACTCTGTCATCAGTGGCTAAGGCCAGAAATCCACACCAAAGAGCAAATCTTGGAGCTGCTGGTGCTGGAGCAATTCCTGACTATCCTGCCTGAGGAGCTCCAGGCCTGGGTGCGGGAGCACCATCCGGAGAGTGGGGAGGAGGCTGTGGCTGTAGTTGAAGATCTGGAACAAGAGCTTAGTGAGCCAGGGAACCAG
Seq A exon
GTGAGAGGAGAAAGATGGACTTCTAGACATTAAATACTAAATGAAAGGTGGGGTTTGGTGACACAGGTTGGTTGGCTATAGCTATATGTATTAGTTCTCTGTTGTGTAACAAATTACCCCTAAACCTTAATGGCCAAGACTATGGTCATCTGATGACAAGACTCAGGTGGGCGGATCCACTTCCAAGATGGTTTACTGGTACAATTGTTGGTAGGGGGCCTCAGCTACTCACTGGCTGTTGGCAGGAGGTCTTAGTTCTTTACCATGTTGGTACTCTTCATGGGGCTGCTTGAGTGCCCTCACAACATGTCAGGTGGCTTCCTCCAGAGAGGAGAAGGAGAGAAAGAGAGAGAAAGGAAAAAGCCACAGTGCTTTTTTGTTGCGGGAAGTCAGGGACCCCAAATGGAGGGACCAGCTGAAGCCATAGCAGAAGAATGTAGATTGTGAAGATTTCATGGACATTTATTAGTTCCCCAAATTAATACTTTTGTAATTTCTTATGCCTGTCTTTACTGCAGTCTCTAAACATAAATTGTAAAGATTTCATGGACACTTATCACTTCCCCAATCAATACCCTTGTGATTTCCTATGCCTGTCTTTACTTTAATCTCTTAATCCTGTCAGCTGAGGAGGATGTATATTGCCTCAGGACCCTGTAATAATTGCATTAACTGTACAAATTGTACAGCGTGTGTGTTTGAGCAATATGAAATGTGGGCACCTTGAAAAAAGAACAGGATAACAGCAATTGTTCAGGGAATAAGAGAGATAACCTTAAATTCTGACTGCCAGTTAGCTGGGCGGAACAGAGCCATATTTCTCTTCTTTCAAAAGCAAATAGGAGAAATATCACTGAATTATTTTTCTCAGCAAGGAACATCCCTGAGAAAGAGAATGTGCGCCTGGGGGTAGGTCTCTGAACTGGCCCCCCTGGGCGTAGCCATCTCTTATGGTTGAGACTGCTGGGGTGAAATAGACCCCAGTCTCCCATAGCACTCCCAGGCTTATTAGGAAGAGGAAATTCCCGCCTAATAAATTTTGGTCAGACCGGTTGATCTCAAAAACCCTGTCTCCTGATAAGATGTTATCAATGACAGTGGTGCCCGAAACTTCATTAGCAATTTTAATTTCGCCTTGGTCCTGTGGTCCTGTGATCTCACCCTGCCTCCACTTGCCTTGTGATATTCTATTACCTTGTAAAGTACTTGATGTCTGTGTCCCACACCTATTCGCACACTTCCTCCCCTTTTGAAAATCCCTAATAAAAACTTGCTGGTTTTTGTGGCTTGTGGGGCATCACGGAACCTACTGACATGTGATGTCTTCCCTGGACACCCAGCTTTAAAATTTCTCTCTTTTGTACTCTGTCCCTTTATTTCTCAAGCTGGCTGACGCTTAAGGAAAATAGAAAAGAACCTACATGAATATCAGGACAGATTCTCTGATACTTTTTACGACTCAGAAGTTATATACCATCTCGTCTGCCTCACTTTCTATTCAGTAGAGTTGAGCTATCAAGTACAGCCCACATTCAGGGGGTTGGGGATGGGCAGTTAGATTCTACCTGGTGGATTTATTTTAAACCACCACACTTGATTGGGCCACTCTTCCCTGTTTTGCTTTTGGGTAATGAATTAAACTCTGGTCCTTCCACTGTGACATCTCTCTAGAAAATGTTTCATATAGTTCCATGTGATATCTTTCATTTAGTATTAGCTTGTACTCCTATAATCCCCCTCTTTAACCAAATATGCCTACCTGCCTTCAG
Seq C2 exon
GCTCCAGACCATGAACATGGACATTCTGAAGTGCTCTTGGAGGATGTGGAACATCTGAAGGTCAAGCAGGAACCAACAGACATACAGCTTCAGCCTATGGTGACACAGCTCAGATATGAATCTTTTTGCCTCCACCAATTTCAAGAACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000235109-ZNF323:NM_001135215:6
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.260 A=NA C2=0.433
Domain overlap (PFAM):
C1:
PF0202312=SCAN=PU(97.9=74.0),PF100984=DUF2336=PU(53.6=40.9)
A:
NA
C2:
PF0202312=SCAN=PD(0.1=0.0),PF100984=DUF2336=PD(44.3=84.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TACCAAGAGACTCCTGGTCCC
R:
AGCTGTGTCACCATAGGCTGA
Band lengths:
353-2122
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)