HsaINT0187289 @ hg19
Intron Retention
Gene
ENSG00000083838 | ZNF446
Description
zinc finger protein 446 [Source:HGNC Symbol;Acc:21036]
Coordinates
chr19:58991297-58992597:+
Coord C1 exon
chr19:58991297-58991386
Coord A exon
chr19:58991387-58991542
Coord C2 exon
chr19:58991543-58992597
Length
156 bp
Sequences
Splice sites
5' ss Seq
CGGGTGAGT
5' ss Score
9.89
3' ss Seq
TGGTTTGCCCCTGCCCCCAGGAA
3' ss Score
10.61
Exon sequences
Seq C1 exon
GGTTACCGCCCCACCAGCCAGAGGCACAGGCCCAGTCAGAGCTGGGGATGCTGCTCACGGGGACAGGCGTCTGCAGAAGCCTGCGCTCGG
Seq A exon
GTGAGTGCCCCACACCATCCAGCCTGAATCACCCCTCCTGTATCGGTGGGACCTGAGCCACCCACTCATGGGGGGACGGGAGCTTGTGCCACGGCCACAAGCCTGAGGGAGGGGTTGCTGAGTGCCGGGACTCACCTGGTTTGCCCCTGCCCCCAG
Seq C2 exon
GAAATGAGAGTGAGGGTCCACCTGGCTGCCCAGAGGCCCAGCCGCCCCAGGGCCCAGGGCCGGCAGCCTGGGAGGGCTTGTCTGGGGCTGCCACTCCTGCCCCCACTGTGCGCCCAGGGACACCGCCAGTGCCCACTCAGCCCACACCTGCAGAGACGAGACTGGAGCCGGCTGCCACCCCCAGGAAGCCCTACACGTGCGAGCAGTGTGGCCGCGGCTTCGACTGGAAGTCAGTGTTCGTCATCCACCACCGGACACACACGAGTGGGCCAGGTGTGCAGTCCCCGGGGCTAGCCACCGGGGAAAGCACAGAGAAGCCACCACAAGGGGAGGTGGCCTTTCCGCACCACCCCCGACGCTCACTCACAGGCCCCCGGAGTTACCCGTGTGAGGAGTGCGGGTGCAGCTTCAGCTGGAAGTCGCAGCTGGTCATCCACCGCAAGAGCCACACAGGCCAGCGGCGTCACTTCTGCAGTGACTGTGGCCGCGCCTTCGACTGGAAGTCGCAGCTGGTCATCCACCGCAAGGGCCACCGGCCGGAGGTTCCATGAGCAGCCAGACAGCACAGTCCCTCGGGGCCTCGGTGTTCTCGGGGCCTGGATACAGCCTCTGGGGCACCAGCAGAAGACTCTGGAGGCAGCAGGGGATGCCAGAGTGAACAAGGGGTCCCAAGCCAGTTCCCTGCCCCTGGTCTGGTCTCCCCCAAAAGACCTGGGTGCAAGGAAAAGGAGCTGCTCTCTCTCTTCTTGCCCCTGCCTCCTAGAGGGAGGTCTGGGTTCCCTTCTATGGCTGACCAGTGCCTGTGGGGTGACTGCCAAGCACCAGGCTCCCTCCCTCCCTGTGACATGGCCTGGGCTGACAACACTCCCTCTCCTGGGACCTCCTTGCCTCAGGTGGGTGTTCAAAAACTGTGCCTTCCCACTCGTCTGTGCAGAGGCTGGGCCTGAGGTCTCAGTGTGGAGAGCAGCAGAAGACCCAGGAAAGCACAGTTGGCTTCCGTTTCTCCTGCTCCCTGTGTGTGTTAGAATTTTAACATAAATTCCACTTTCATAATA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000083838-ZNF446:NM_017908:6
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.895 A=NA C2=0.612
Domain overlap (PFAM):
C1:
PF0135222=KRAB=PD(0.1=0.0)
A:
NA
C2:
PF0009621=zf-C2H2=WD(100=12.5),PF134651=zf-H2C2_2=WD(100=13.6)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGTCAGAGCTGGGGATGCTG
R:
ACGTGTAGGGCTTCCTGGG
Band lengths:
255-411
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)