HsaINT0187636 @ hg19
Intron Retention
Gene
ENSG00000130544 | ZNF557
Description
zinc finger protein 557 [Source:HGNC Symbol;Acc:28632]
Coordinates
chr19:7081981-7087978:+
Coord C1 exon
chr19:7081981-7082063
Coord A exon
chr19:7082064-7082888
Coord C2 exon
chr19:7082889-7087978
Length
825 bp
Sequences
Splice sites
5' ss Seq
ATGGTAAGA
5' ss Score
9.48
3' ss Seq
TGTCATCTCTTAATCAATAGGAG
3' ss Score
8.11
Exon sequences
Seq C1 exon
ATGTGGAGAATCCATTTAAAGCCAAAGGGTTAACTCCTAAGCTGCATGTTTTTCGAAAAGAACAATCTAGAAATATGAAAATG
Seq A exon
GTAAGACTAACATGGGTGATTCCTGGTTTTTTTCATGGTAGAATGCCCTACATGAGAAAAGCCACAAGGACTGGCCTTGTTGGCCAGGCACAGTGGCTCATGCCTTTAATCCCAGCACCTTGGGAAGCTGAGGCAGTTGGATCATGAGGTCAGGTCAGGAGTTGGAGACCAGCCTGGCCAATACGGTGAAACCCCATCTCTACTAAAAATACAAAAAAAACTTAGCTGGGTGTGGTGATGCGCACCTGTAATCCCAAATACTTGGGAAGCTGAAACAGAAGAATCACTTGAACCCTGGAGGTGGAGCTTGCAGTGAGCCGAGATTGTGCCACTGCACTCCAGCCTGGCGACAGAGCAAGACTCTGTCTCAAAAAAAAAAAAAAAAAAAGTGGCTTTATTAAATAGTTATTAAAGGAAAGTGTCATTTTTTTCAAAGATAAAGTAGTACCTCTGGAGAGATACTGTGAAATTATTTTGAATTTGGAGAAAAGCATTAGTTAGCCCCAAACTTGTTTTTCCTGAGAATTCCCACAAGTAAATATTTCCAGTAGTCTGAGTCAGATATTGGATATTTGAAAAAGAAATTAGCCTTAAATTTATCAAAAATACTCTGTGAATATGATAAAGATTTGTAGAAAGAATCCATCTTCTTTAAATGCTAAGAATTCAAACTGACAGAAGCCATGTACCAGCACTCATGATGGCAAAAACATTAATTCCAATACTATGATACACAACAGAATTCCTGGGAGAGGAAATTCCTCTGACAGCATTCAATGTTAAAAATATTATAAATGGTACTTATTGTCATCTCTTAATCAATAG
Seq C2 exon
GAGAGGAATCATCTTGGAGCAACACTCAACGAATGTAATCAGTGTTTTAAAGTCTTCAGCACAAAATCTTCCCTTACACGGCACAGGAAGATTCATACTGGAGAAAGACCCTATGGCTGCAGTGAATGTGGGAAATCCTACAGCAGTAGATCTTACCTTGCTGTTCATAAGAGAATCCACAATGGGGAGAAACCCTATGAATGCAATGACTGTGGGAAAACCTTCAGCAGCAGATCTTACCTTACTGTTCATAAGAGAATCCACAATGGGGAGAAACCCTACGAATGCAGTGACTGTGGGAAAACCTTCAGCAATTCCTCATACCTCAGACCGCACTTGAGAATTCACACTGGAGAAAAACCGTACAAATGTAACCAGTGTTTTCGTGAGTTCCGCACTCAGTCAATCTTCACAAGGCACAAGAGAGTTCATACGGGGGAGGGTCATTATGTATGTAATCAGTGTGGAAAGGCTTTCGGCACGAGGTCATCTCTTTCTTCGCACTATAGCATTCATACAGGGGAGTACCCTTACGAATGCCACGATTGTGGGAGAACCTTCAGGAGGAGGTCGAATCTGACACAGCACATAAGAACTCATACTGGAGAAAAACCCTACACATGTAATGAGTGTGGGAAATCCTTTACCAATAGCTTTTCTCTTACAATTCACAGGAGAATACATAATGGAGAGAAATCCTATGAGTGCAGTGATTGTGGAAAATCCTTTAATGTTCTCTCATCCGTTAAGAAACACATGAGAACTCACACTGGAAAAAAACCCTATGAATGTAATTATTGCGGGAAATCCTTCACAAGTAACTCCTACCTTTCTGTGCATACGAGAATGCATAATAGGCAAATGTGAATTCAATAACTGTGGGAAAAGCATTCATTGATCTTTCATGCCTCAGATAACATGAGCAAACTCTAACAAGATGTATGAATCACCTGCTACTGTGTAACAAATTACCCCCCAAAATTTTGTGGCTTCAAACAAAAACACTTGTTATCTCAAAATTTTTGTAGGTCAGGAATTCAGAAACAACATAGCTCTATAGTTCTTCAGGATATCTCAAGAGGTTACAGTCCAGATGTCAGCAGAACTGTAATCATCCAGAATTGTTACTGGTGAAGGGACCACTTCCAAATGGCTTACAAGCCCGACAAGTGCATGCTAGCTGTTTCCAAGGGAGCTGCGCTTCCAAATCACGTAGGCCTCTCAACAGGGCTGAGTTTCTTTATGGAAGCAACTTCTCCCCAAAGCCAGTGATCTAAAGGAGCCAACACAGAAAGCATAATGTCTTTTATGACCTAGCTTCAGTGAGATATGTTTTCATGTCCCTGTTACATTGGTCATACACACCAATCCTGATACAATGTGGAAGAACACCACAGGAGGTATGAACAGTAGACATTTGGAACCATCTGGAAAACTTGCCATGAAATCAGTGGAGGAAAGCCTTCAGCTGACCCTCATTTTTTTTTTTTTAAGACAATGTCTCACTCTGTCACCCAGTCTGGAGCGCAGTGGTGTGATCACAGCTCACTGCAGCCTCTACTTCCTGGGATCAAGTAATTCTCCTGCCCCAGCCTCCAATGTAGCTGGGACTACAGGTGCATGACACCATGTCTGGCTAATTTGTTTTTTTTTAAACTAGAGGGAGGGTTTTGCCATGTTGCCCAGACTAGTCTCAAACTCCTAGGTTCAAGCAGTCCTTTCATCTTGGCCTCCAGAAGTACTGGGATTACAGGCATGAACCACCATGCCCAGCCAACTTCTAAACTGATCAATATGGGAGTAGCATTCAATCACCCACAGGTTAACTCACTCTAGAGAGAAATCTTGTGAGTGTAATCTGTATGGTAAAACTTTGAGCTCAAACTTTCCCCCTACCAAAAAAAAAGTATCTACTGGGGAGCTGCCCAGGTAATGCAGTAGCTGTAGGAAAGCCTTCAGTGATGGCTTCAGGGAGTCACATGACAACTCACAATAAGGGGAAACCCTGTGTGTGGCATCAAAAATGGAAAACCAGGGGACACTCATTCCTTAAGTCACATTTCGGAGATCATACAACAGAGGAATATGTTGAGTATACACAGTGTTGAAAAGCCTGTGACACAAACAGTCATATTACCAAGCACAAGACAGTATAGTTTGGTATGCTATAAAAGCCTTGAATATTCTCTCCATTTTTAAGAAGTGAGATTCATACTAGAAAAACCATTGAATTCCATCAGTATTAGAATGTCATTTTTCCACATTTTTAGGAACCTAACTCAGTGTAAGATAACAATTTATACAATTTATTTTTTGAGACAGGGTTTCATCTGTGCCCAGGCTGTAGTGCAGTGGTGCAATCTTGGCTTATTGTAACCTCTGCCTCCCAGGCTTAAGGGATCCTCCCACCTCAGCCTCCCAAGTAGCTGGGACTGTAGGCATGCACCACCATGCCTGTCTAGTTTTTGTAAAGATGGGGATTCACCATGTTTCCCAGGCTGCTCTCAAACTCCTGGGCTCAAGTGATCCACCTGCCTCAGCCTCCCAAAATGCTGGGAATACAGGAACGAGCTACCACTCTCAGCCAGAACTTCTTAAGATAAAGGATGAGGGAATGTTTTCAGTGATACCTCTTATATTAGGAAAAATATGTAAATGTTCCTTGGATGCAATACTCACGAGTGTATTAATTTCAGAAAAATTTTCAGTGATTCCTCCCTTTATGCATGAGAGAATTCATTTAGAGGAAGCCCTAGGAACGTAATCAATGTTAGGATGCCTCATCTCTTAACTGAGTGGCCACGCAGTAACTTAGAACAAAAGGTGTAAGTGCTATGAATGTGGAATTACCTTCATCAATGTCTCATTTGTAGGTTGGGCCACTAGCTCGTTCATTTTCAGTCTTTTAATATAAACATTTATGGCTATAGTGGTCCTGAAAATCTTACTACCTCGTTTTATATACAGTGTATTTATTATAATTCTAAAACATCAATACACCAAATATTCAGAAAGGTATTTCCAAACAGCTCCTGAGTGATCTAGTTTGTTATAATAGAAATTAGACATTTGCCAGGTGTGGTGGCTCACACCTATAAACCTAGCATTTTGGGAGGCTGAGGCGGGCAGATCACCGGAGGTAAGGAGCTTGAGACCAGCCTGGCCAACATGGTGAAACCCCGCTTCTACTAAAAAATACAAAAATTAGCCGGGTGTGGTGGCAGGCATCTATAATCCCAGCTACTCAAGAGGCTGAGGAAGGAGAATCACTTGAACCCGGGAAATGGAGGTTGCAGTGAGCCAAGATCATGCCACTTCACTCCAGCCTGGGCAAAAGAGTGCAACTCTGTCTCAAAAAAAAAAAAATCAGACAATATTTGATATATTTTTTTCTAATTTAATAGTATTTTGCCAGAGTACATGGACTTTGTGATTTTGGTTGTTTTCTCTTTGTGTCCTAATATAGCAAATACTGTTTCTTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTCTTGCTCTGTTGTCCAGGCTAGAATGCAGTGGCGCGATTGTGGCTCACTGCAAGCTCTGCCTCCCAGATTCACGCCATCCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGTGCCCATCACCATGCCCGGCTAATTTTTCATATTTTTAGTAGAAATGGGGTTTCACTGTGTTAGCCAGTATGGTCTCAATCTCCTGACCTCGTGATCCACCTGCCTCGGCCTCCCAAAGCACTGGGATTACAGGCGTGAGCCACCATGCCCGGCACAAATACTGTTTCTTAATGTTCATTCTCCCTACTTAAAGAAAAAGATAAGTTGTCAATGAGCAGTATTGAAAATGTACAGTGGGGCCAGGCGCCATGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGCGGACCACCTGAGGTCAGGAGTTCAAGACTAGCTTGGCCAACGTGGTGAAACCTCGTCTCTACTAAAAAAAATACAAAAATTAGCTGGGCGTGATGACAGGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCGCTTGAGCCTGGGAAGCGGAGGTTGCAGTGAGCCGAGATTGCACAACCACACTCCAGCTTGGGCGACAGAGTGAGACTCCATCTCAAAAAAAGATGTACAGTGTACTAGGCTTTCCTGAAGCTTAGACAGGCTTTATCCCACTCTGCTGGCTAAAAGAAGTAGGAATAACGCACTGGGTGAGACACCGTCTGGCTTATTCTCATCTATTTTCTTTTCATTCTTTTGGAAAGTGGACACAAAGCATAGAGTTAAAAGAGCTTTTTTTTTTTTTTTTTTTTTTTTCTTCACTGTGGTGATAAAAACCACAGTGCAGGGGCTGGGCGTGGTGGCTCACGCCTGTAATCCCACCACTTTGGGAGGCCAAGGCAGGCGGATCACCTGAGGTGGGGAGTTCGAGACCAGCCTGATCAACATGGAGAAAACCTGTCTCTCCTAAAAATACAAAATTAACCGAGCATGTTGGCGCATGCCTGTAATCTCAGCTACTTGGAAGGCTGAGGCAGGAGAATTGCTTCAAACTGGGCAGAGGTTGCAGTGAGCCAAGGTTGACCCACTGCACTCCAGCCTGGGCAACAAGAGCAAAACTCCATCTCAAAAAAAAAAAAAAAGAAAGAAACAGTGCCGAAAAATCACAATGATTTGAGTTCTTCAAAAACCTTTGATTGGCTGCATTGGCTCTGTTCTGCATATTACTAGACTTCTTACATGATCACAAGTAACCACTAATTGGTTAAAACCAAAGAGAGAGAGAGAGAGAGTGTGTGTGTGTGTGTGTGTGTTTGGTTGGGGGGTGTTGTGTTAGCTTCCAGGTGAATGCATTATCTGTTAATCCTGTTTATTGATCTGTTTTTATAAGTGCTCCATGATTCTCTGAAAACAGTATACTATGTATCTAATTTTTGGATACAGGATGGACATACGTACTCAAACTGTGTTTTTCAATTTGTACTGTATTTGTTTCTCTCGACCTGACTTAGTGATAGAGGTATATTAAAGTCTTCCACTAGCATGGTAGATTAACAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000130544-ZNF557:NM_001044387:7
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.179 A=NA C2=0.069
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF134651=zf-H2C2_2=WD(100=9.0),PF134651=zf-H2C2_2=WD(100=9.0),PF134651=zf-H2C2_2=WD(100=9.0),PF134651=zf-H2C2_2=WD(100=9.0),PF134651=zf-H2C2_2=WD(100=8.7),PF134651=zf-H2C2_2=WD(100=9.0),PF134651=zf-H2C2_2=WD(100=9.0),PF105204=Kua-UEV1_localn=WD(100=34.6),PF134651=zf-H2C2_2=WD(100=9.0),PF097235=Zn-ribbon_8=WD(100=8.3),PF134651=zf-H2C2_2=WD(100=9.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGGGTTAACTCCTAAGCTGCA
R:
CCCACAGTCACTGCATTCGTA
Band lengths:
358-1183
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)