HsaINT0188056 @ hg19
Intron Retention
Gene
ENSG00000188295 | ZNF669
Description
zinc finger protein 669 [Source:HGNC Symbol;Acc:25736]
Coordinates
chr1:247265289-247267674:-
Coord C1 exon
chr1:247267241-247267674
Coord A exon
chr1:247265416-247267240
Coord C2 exon
chr1:247265289-247265415
Length
1825 bp
Sequences
Splice sites
5' ss Seq
CAGGTAGTG
5' ss Score
6.13
3' ss Seq
ACATGTGTGGAATGTTCTAGGAC
3' ss Score
6.92
Exon sequences
Seq C1 exon
GCCTGGCGGTTGCTTTGTCTCTCCTTCGCCGGAGCCGGCTCTTCCTGTTAGTCTCCGCTGCTAGTTCTTGGCTCTGGGAGGCCCAGGTGGCTCTGCAGCAGCCTCTGCCACCCTGTGACCTGCGAGTATTGGGACATCCCTAGCTGACGCCAGGACACCCGGGAAGCCGAGGAATGGTGAGTGGACTGCGCCTGGCTTCCCGAAGTGGAGAAGAGGGCTGGTTGAAACCTGCTGTGGCGCGACTCGGGCCTCCACGCCATCGGCTCCGGAACCTGCGGACCGAGTCGCCGTGGCGTAGCCGGGGCTCAGTCCTCTTCTGTTCAGGGCCGGGCCGGGCGGGGCGGGCAGCGGAACCCCTGCATCCTGTCTGTACCTGCGGGCGCCACTTCCGCCGGCCGGAGCCCTGTCGGGAACCCCTCGCCTCCCCTATCCAG
Seq A exon
GTAGTGTGGTGACCACGGGAGGGTGATGCGGGAGAGCCCCGACTCGGTGTCTCGGTGTGCGGGGTTCCAGCATGGGAGGAGCTGTGGTTCATGGGGCTTCCAGTCCCACCTTTCTTCCCCTAAAATTAAGCCGAGGCTTTGTTAAAACGTTAAACCGTGTGTTTGAGCAAACGGCGATTCATAAACCAGGTACCGCAGTCATGGTTTGTGGTTTGGGGTCCACAGAAGGGGCGTAAATGAGAGGCTTTGATAAGGTTAATGAGGAAGCAAACCATATTCTTTTTTTTTTTTTTTTTTTTTTTTTTTGGAGACGGAATCTCGCCCTGTCGCCAGGCTGGAGTGCAATGATGCAGTCTCACTCATTGCAACCTCTGACTCCCGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCGAGTAGTTGGGATTACAGGCGCCCGCCACCACGCCCAGCTAATTTTTGTATTTTTGGTAGAGACAGGGTTTCGCCATGTTGGCTAGGTTGGTCTCGAACTCCTGACCTTAAGTGATCCGCCCGTCTCGGCCTCCTAAAGCGCTGAGATTACAGGCGTGAGCCACCGCGCTCGGCCAAAATATTTTTCTGTTTACAAACATTTTACATGAGAGGAAAGCGGAGAATAAACCATCTGACACTCTACTGTAAAAAAATCTTTGTGCCTCTCTTCATCTTTCCTAAGTGTGCATATTACCAAAATGTCTTTAGGTTGATGTCCCCCTGTGAAAACTTTACAGGGTGTTGTGTCCTCAGCCCTTGGTCTGCTTGCTCATCTCTCTGCTAATACTGTGCTGTCCTGAATATTTTTGGTTGAAAATCTTAAAAGTATGTTAGGCAAGACATAACTCTTTTTTTAGATGACTGAAAATCATTAGACATTTGTCATTTTTACTAGGTATGAAAAACTAGTTTTTCTTGCCTAAAAAAGCCTGATTTGGGAATTTATGTGATTTCACAGGAATAGCATCTGGAAGTGGTGACATTAATGTCATTTTAAAAAACATGTGCCATATTTCCTCTTATTCCATTCTGCCTTGACATTGTGCAATAGAAATTTAAAAATTGTATTAGTAAATTGTTAAATATCAATTATTGGTTTTATTTACTACTCAATTAAATTTAATAAGCCTATTCTCTCTTGGTGTAATCACATGGAATGGGCTCAACTCCCCAATTAACAAGTGACAGCACATATAAAATATTGTCTACCAGGGAAACTCATTAAACACTTAGTGTTCAGACTGTGTTTTGGTGTCTGGTTCCCTAAGCACCACTGCAGTGACACAAAATAATAGACCTTTAGCAGAAAAAGTTTTGGCAACTATATTGCATAAACCATTTAGATGCAGTGAGTCATTCTTATTACTTAGGTTGGTGGAATCCCTTTCAAAATGTAAGTTACTAATACAAACAAAGATTGAACTTTGTGAGCAGGCATTTTTAAGAATAAGTAGTCTTAGGACTGATATTATTAACTCACTTATGCACATCAGGTAGGACTTTATTATGGCAGATACTAGAAATGTACGAAGTGAAATTAAGAGGTAACCTAGCAGCACATCTTACTCCCTGGATTCTCTAATGAGATGGGTATTTCCACTTTGCTGTTGCCTTTTTGAATAGTTCAATTCTAGCATTAGTACTGCTGTGTGGGAGGGAGTATGTGTGAACAGAGTAAGAGTTGTGACAATCAAGTCATAGAATAAATGCTTGGAAATTATCAAATCATGTAAACAGCTTATGAATTGAGTATAGATTCCCAGTGCTGTCAGTCTCACCCATCCTTCTATCCACATGTGTGGAATGTTCTAG
Seq C2 exon
GACTCGGTGGCTTTTGAGGATGTGGCTGTGAACTTTACCCAGGAGGAATGGGCTTTGCTAGATTCTTCTCAGAAGAATCTCTACAGAGAAGTGATGCAGGAAACCTGCAGGAACCTGGCTTCTGTAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000188295-ZNF669:NM_024804:1
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.146 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0135222=KRAB=WD(100=95.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGACCTGCGAGTATTGGGACA
R:
CACATCCTCAAAAGCCACCGA
Band lengths:
343-2168
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)