HsaINT1002770 @ hg38
Intron Retention
Gene
ENSG00000160323 | ADAMTS13
Description
ADAM metallopeptidase with thrombospondin type 1 motif 13 [Source:HGNC Symbol;Acc:HGNC:1366]
Coordinates
chr9:133454415-133455603:+
Coord C1 exon
chr9:133454415-133454619
Coord A exon
chr9:133454620-133455284
Coord C2 exon
chr9:133455285-133455603
Length
665 bp
Sequences
Splice sites
5' ss Seq
GAGGTGAGC
5' ss Score
8.7
3' ss Seq
CTCCTCCCCTCTCTTGGCAGTGC
3' ss Score
10.34
Exon sequences
Seq C1 exon
GTGGAAAGTCATGTCCCTTGGCCCATGTTCGGCCAGCTGTGGCCTTGGCACTGCTAGACGCTCGGTGGCCTGTGTGCAGCTCGACCAAGGCCAGGACGTGGAGGTGGACGAGGCGGCCTGTGCGGCGCTGGTGCGGCCCGAGGCCAGTGTCCCCTGTCTCATTGCCGACTGCACCTACCGCTGGCATGTTGGCACCTGGATGGAG
Seq A exon
GTGAGCACAGCGGGCACTCGGAATCCCTATGGGGCTGGGGTGGGCATCAGCTGTGGCTCCTCATGTGTGAGGGAGTCTAGGAGGCATTGGCTCATCGTGTCCCCTGAAAGGAAGGAGAGAGCTGCGCCCGTTGGTGAGGGGGCACCTAGAGGCAGAGAGACAGAGGGCCTAGAGACCTGCGGGCAGCTAGGACTTAAGAGGCCCTTAGGTTTGGGGACGCTGGAAGATGAATGGCAGGCCACTCAGCTCTACACAGATGAGGGAATGCCAGCTGTGCCACGCACCTGGCAAGGCAGGACAGACAAGGGTAAATGGGGTTCAGGCTGCCCCCTGGAGGGGCTCGCTCATGGTGTGGAGGGGGCATAGGGGCACAGCAGACAGAGATGAGCCGCAGCCCCGCAGACCTGCTTGCTCTAAGGCTTGGAGGGACAGAGAGGCCGTGAGGGTGACAGGGACCCAGACTTGAATTATGGCTCCTCCCACCTATATGACCCATGCAAGGTGCCCTCTCTGAGCCTCAGTTTTCTCATCTGTGGAATGGAGACACTTAACTGCCTCCCAGCTTGTACAAGGATTATATTGGATCACTCCTGGCCTGTGGTTACCACTGTCCTTGTCACCTTCTGGCAGGGTCAGCTGTGACTCCTCCTCCCCTCTCTTGGCAG
Seq C2 exon
TGCTCTGTTTCCTGTGGGGATGGCATCCAGCGCCGGCGTGACACCTGCCTCGGACCCCAGGCCCAGGCGCCTGTGCCAGCTGATTTCTGCCAGCACTTGCCCAAGCCGGTGACTGTGCGTGGCTGCTGGGCTGGGCCCTGTGTGGGACAGGGTACGCCCAGCCTGGTGCCCCACGAAGAAGCCGCTGCTCCAGGACGGACCACAGCCACCCCTGCTGGTGCCTCCCTGGAGTGGTCCCAGGCCCGGGGCCTGCTCTTCTCCCCGGCTCCCCAGCCTCGGCGGCTCCTGCCCGGGCCCCAGGAAAACTCAGTGCAGTCCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000160323:ENST00000371929:24
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.291
Domain overlap (PFAM):
C1:
PF0009014=TSP_1=WD(100=59.4),PF0009014=TSP_1=PU(12.2=8.7)
A:
NA
C2:
PF0009014=TSP_1=PD(83.7=80.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CACCTACCGCTGGCATGTTG
R:
CTGCACTGAGTTTTCCTGGGG
Band lengths:
349-1014
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains