HsaINT1024117 @ hg38
Intron Retention
Gene
ENSG00000264424 | MYH4
Description
myosin heavy chain 4 [Source:HGNC Symbol;Acc:HGNC:7574]
Coordinates
chr17:10448864-10450649:-
Coord C1 exon
chr17:10450453-10450649
Coord A exon
chr17:10449048-10450452
Coord C2 exon
chr17:10448864-10449047
Length
1405 bp
Sequences
Splice sites
5' ss Seq
CAAGTATGT
5' ss Score
7.44
3' ss Seq
CATACTGACCCAATTTTCAGGAA
3' ss Score
8.04
Exon sequences
Seq C1 exon
GCCAAGAGCACTCTGGCCCATGCCCTGCAGTCAGCCCGCCATGACTGTGACCTGCTGCGGGAACAGTATGAGGAGGAGCAGGAAGCCAAGGCTGAGCTGCAGAGGGGAATGTCCAAGGCCAACAGTGAGGTTGCCCAGTGGAGGACCAAGTACGAGACGGACGCCATCCAGCGCACAGAGGAGCTGGAGGAGGCCAA
Seq A exon
GTATGTGCTTTTAGTGCAGGGGAGCAGGAAGAAATAAAAGTAAAGGCAGTGAAGGAAAAATAGAAGAAAGAGAATATTCCGGGCTTGGGGACACATGAAAGACTTCAGCTTATTTTATTATAGGTTGGTGGATTCCACCATATTCTTCTTCTTAAAGCCCAGTGTATGTCCACTGGAGAATGGAATGAGACCAGATCCCTCCACCCATTCTTGTCCAGAAGCATCTTAAATTTCTTTCCACCAAGATGGATTATTAATTATCAGAATATTATTTATGAATTAAATAGAATTAGTATCTTTTAATAGAAGGAAAAATTGAGACATTGAGACTCTCTGGTAAATTATTATGAGTATTACAATTAACAATAATCAGTTTTTCCTCAGATGGAGTATTGAATGTTTATATTAAGGTTGTCATATGCTGTCATTATTTCAACTAACAACCTATATCAATGGATGTATTCACTAATTACACGTACTGTTTGCGGACTACAAGTCATGAGATTTACAGATTTACACATAGAAGGAAAAAAAGCATTATACTCCTAGTGAAAGAAGCCTTTCTAAATTTAATTTATCTCAGTAGTTGTTAGAATTAAACAGGATGAAAGAGTTTGTAGCAAGCATTTCCAGAGAGAGTTCTAGATAAGAGTGTGGGCTGGGAAAGGTCATGAATTACATAGGTTGGTGAAGAGTAGTAGACAAGATTTTAGAGGAAATTTGGGAAATGCAATAATGCAGTAATATTTATTATCAAAGGCCACCAAATCCAGAAAGTTACTGATTCATTGTATGACCTTGAACATATCACTCTGGGCCGCAGTTTCCTCATTTGCAAAATAAACAGAACCATACTAGAAAATGCTTAAAGATACTACTCAATGCTACCATTCCTTGGTGATATGCTTCCTGTTCATGGTTGCCATTTCTTCCTCAAAGTAAATAAAACTCAGCCCTTTTCCACAAGTAGTTACAGATCTCTAAATCCCAGGTTTCAAAAGAGAAATGTACTGTCTCTTCCTGTTTTCTACTTCTCACCCCAGGCAAAGTTCAAGAAAATGTGCCACACTATAGAGGGCCAGCTTAGTGAAATAAAAACAAAGAAAGAGGAGCAAATTTTCACATTGCTCACTCAGCTCTAGTGCTAACTTATATTCTCTTTCTCTCATACACACACATACACACACACAGGTGCTTCGTAAATATGTTTGGCAATACCTGAGATGGATAAAAATAAGAACTCAACAGGGAAAACAGAATTCTAAGAGAGTGAAAATGTTTAGAAAAATTCAACAACTTGTAGACAACTCTTGGGGAAATATGCTTTCCTAGTCAGCAGCTTTATAAAGGGCACTGTGGTGACTCTGAGTCTGCTCTTGGTCACTCATACTGACCCAATTTTCAG
Seq C2 exon
GAAGAAGCTAGCCCAGCGTCTGCAGGATGCAGAAGAACATGTAGAAGCTGTGAATTCCAAATGTGCTTCTCTTGAAAAGACAAAGCAGAGGCTACAGAATGAAGTAGAGGACCTCATGATTGATGTGGAACGATCTAATGCTGCCTGCATAGCTCTCGATAAGAAGCAAAGAAACTTTGACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000264424:ENST00000255381:30
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.591 A=NA C2=0.290
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(7.6=100),PF0003816=Filament=PD(19.7=42.4),PF059116=DUF869=PD(25.0=34.8),PF0003816=Filament=FE(21.9=100)
A:
NA
C2:
PF0157614=Myosin_tail_1=FE(7.1=100),PF0003816=Filament=FE(20.5=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAAGAGCACTCTGGCCCATG
R:
CAGGCAGCATTAGATCGTTCCA
Band lengths:
342-1747
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains