HsaINT1025124 @ hg38
Intron Retention
Gene
ENSG00000204301 | NOTCH4
Description
notch 4 [Source:HGNC Symbol;Acc:HGNC:7884]
Coordinates
chr6:32204137-32210936:-
Coord C1 exon
chr6:32210752-32210936
Coord A exon
chr6:32204390-32210751
Coord C2 exon
chr6:32204137-32204389
Length
6362 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGA
5' ss Score
9.22
3' ss Seq
CTAATCCTCTTTGTCTGCAGTGT
3' ss Score
8.5
Exon sequences
Seq C1 exon
GCATAGACGTCTCTTCCCTTTGCCACAATGGAGGCCTCTGTGTCGACAGCGGCCCCTCCTATTTCTGCCACTGCCCCCCTGGATTCCAAGGCAGCCTGTGCCAGGATCACGTGAACCCATGTGAGTCCAGGCCTTGCCAGAACGGGGCCACCTGCATGGCCCAGCCCAGTGGGTATCTCTGCCAG
Seq A exon
GTGAGAGGGTCTGCAGGAGAAGGGGGAGGAAAGACAAGGGTGGGCTGGATGGGAGAGACAGTAGTGACTGAGGGAAGACCCAATGTATCCATTTCACCTCCTTTTATTTTTTTTAACCCCACACACCCAACTAACCACAAAGTCATGCCACTTTATCTCCTGAAGTTTTCTCAAGTCTGTGCTTTCACCTTCACCCTTTGTCCCACTGCCTGAGTCCTGACCTTTGTTGCGTTCCAGATAGATACTTGCATCAGCCTCCTAACTACAGTCTCTGCCTCCACACTTGTCCTTCTATAGGTTCAGCCTTTACCCCGTGGCCAGGGTACTCTACTGAAAATGTCCAGTTGACCTGTCTCTCCCCTGCTGAACCTTCGGAGGCTGCCCGCCTCATTCTGAATAAAGTCCAAGGCCTGCATGACCCAGCCCTGCCTGCCTCTCAGGCCTCAGCTCTCCCCATCCCACCCTTCTACTCTCTGCTCCAGCAACATGAAACTGCTGCTGACTTTGCCACGTACCCCATACTGATTCTTGCCTCTCAGCCTTTATCCCTGCTATTGACACTACCTGGAATGGCCTTCCCAACCCCTCTTCCACAGGCTGGTGTTCAGGAGGCATCTTCTTCAGGAAGATGTCCCTAACTTCTCCCCAGGCTGGATTAGGGCCTCTTCTTTGTGGTCCAGGTCACTAAGCCAGGAGAGGCAAAGCTGGCATTCAAGTCTAAGCAGCCTGATTCATATGCTCAGAACCACAACTTTTTTGTGTGTGTGGTTGCCATTTTATTTTCTTTTGTTATTGACAAACGGTAGTCATACGTATCTATGGGGTACATGTGAGTTTTTTGGTTTCTTTTTTTTTTTCTCTCTCGTTTTTGGAGACAGAGTCGCTCTATCCCCCAGGCTGAAGGGCAGTGGCATAATCTTGGCTCACTGAAACCCCCGCCTCCCAGGTTCAAGCAGTTCTCATGTCTCAGCCTCCCGAGTAGCTGGGATTACAGGAACGCGCCACCACGCCTGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGGCAGGCTGGTCTCAGAACTCCTGACCTAAAGTGATCCACCCGCTCAGCCTGCCAAAGTGATAAGATTACAGGTATGAGCCACCGCACCTGGACACATGTGATATTTTGATACATGCATACAATGTATCATGATCAAATCAGGGTAATTGGGATATCTATCATCTCAAACATCATTTCTTTGTGTTGAGAACATTTCAAATCTTCTCTCCTAGTTATTTTGAAATACAAATTGTTAACTATCACCATCCTTCTCTGCTATCTAACACTAGAACTTATTCCTTCTATATGACCATAATTTTGTATCCATTAACCAACCTCTCTTCATCTCCCCCTCCCTGCCACCCTTTCTAACCTCTGGTAACCATCATTCTACCCTACTTCCATGAGACTAACTTTTTTAGCTCCCACATATGAGTGAGGAGCAATATTACACATGCAATAGGAGGCTGATGCAAGTATCTACCTGGAATGCAAGAAAGGTCAGGACTAACTAAGGCAGTGGCACAAAGGTGAAGGTGAGAGACATGCAATATTTGTCTTTCCGTGCCTGGCTTATTTCACTTAACATAATGTCCTTCAGTTTCATCCATGTTGCTGAAAATGATAGGATTTCATTCTTTTTCTGGCTGAATAATATTCCATTGTGTCTATATGACACAGTTTCTTTTTTCCATTCATTTGTTGATGGCACTTCAGTTAATTCCATATGTTAGCTATTGTGAACAGTGCTGCAATAAATATGGGGATGCAGATATCTCTTCAAGATACTGATTTCCTTTGGATATGTAATGAACAGTAGATTGATCACATGGTAGATCTATTTTTAATTTTTGAGAAACTTCCATACTTTTCTCCATACTGGCTGTGTTAGTTTACATTCCCACCAACAGTGTATGAGGGTTCCCCTTTCTCTGCATCCTTGCCAGCATCTGCTATTTTTTGCATTTTTTTTCCTTTTCTGAGACAGAGTCTTGCTGTGTTGCCCAGGCTGGATCACAGTGACTTGATCTCAGCTCACTGCAACCTCTGCCTCCCAGATTCAAGCGATTCTTGTACTTCAGCCTCCCAAGTAACTGGGATCACAGGCGTGGACCACCATGCTTGGCTAATTTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGATGGTCTCGAACTCCTGACCTCAAATGATCTTCCCGCCTCAACCTCTGAAAGTGCTGGGATTACAGGCATGGGCCACCACACTTGGCCCTTGTGTTTTCAATAACAGCCACTTTAACTGGTGTGAGATGATATCTCATTGTGGTTTTGATTTACATTTCCCTGATTTGCATCCATATACCTGTTGGCCATTTGTATGTCTTCTTTTGAGAAATGTCTGTTCAGATAATTTGCTCATTTTTTAAACCACATTATTTGTCGGTGGTGGTAGTGGTGGTGTTTGCTGTTGAGTTCCTTATACGTTCTGATTATTAATCCCTTGTCAGACAGTTTGCAAATATTTTCTTCTATTCTGTAGGTTGCCTCTTCACTCCATTAATTGTTTCCTTTGCTGCACAGACACTTTTTAGCTTGATGTAATCACATTTGTCTGTTGTTGCCTTTGTTGCCTGGCTGTTGAGGTCTTACCCAAAAAACTTTTGCCCAGACCAATGTCTTGAAGCATTTCCCAAATGATTTTTTTTTTTTTTTTTTTTTGAGAAGGAGTCTTGCACCGTCGCCTGGGCTGGAGTGCAGTGGCGCAAATTTGACTCACTGCAACCTTTGCCTCCTGGGTTCAAGCGATTCTCCTGCCTTAGCCTCCCAAATAGCTGGAATTTACAGGTGCCCACCACCACGCCCAGCTATTTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTTGTGTTTGAGGATTACAGGTGTGACCCACCGTGCCCGGCTGAATTTTTTTTTTAGTGGCTTCAAGTTTCCAGCTGTACATGTAAGGCTTTAATCTATTTTGTATATGATGACAGATAGAGATTTAGTTTCTTTTTTTCTTTTTTTTTGGGGGGGGGGGATAGAGTCTTGCTCTGTTGCCCTGTTGCCCAGTCTGGAGTGCAGTGGTATGATCTCAGCTCACTGCAACCTCCACCTCCCAAGTTCAACTGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGAACTACAGGTGCACACCACTACGCCCGGCTAATTTTTGTAATTTTAGTAGAGATGGGGTTTCACCATATTGGTCAGGCTGGTTTCAAACTCCTGACCTCAGGTGATCCACCCACCTCCGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCCCGCCCGGCCTAGGTTTAGTTTCTTCTGCATATGGATATCCAGTTTTCCCAGCACAATTTATTGAAGAGAGTGTCCTTTCCCCAGTGTGTGTACTTGGTGCCTTTGTTGAAAGTAAGTTGGCTGGCCGGGAGTGGTGGCTCATGCCTGTAATCCCAGCATTTTGGGAGACCAAGGCGGGCAGATCACAAGGTCAGGAGTTCGAGACCAGCCTGACCAACATAGTGAAACCCCCGTCTCTACTAAAAATACAAAAATTAGCCAGGCATGGTGGTGCGCACCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGTGGAGGTTGCAGTGAGCCAGATCGTGCCATTGCACTCCAGCCTGGCAACAGAGCAAGACTCCATCTCAAAAAAAAAAAAAGGAAAGAAAAGAAAAAAGAAAGTAAGTTGGCTGTTAAATGTTTGGACTTGTTTTTCTGGGCTCTCTATTACATTCCATTGGTCTATGTGTCTGTTTTTTATGCCAGCACCATGCTGTTTTGGTTACTATAGCTTTATAGTATATTTTTAAGTTAGGTAGTGTGGTACCTCTAGCTTTGTTCTTTTTGCTCAGGACTGCTTTGGCTATTTGGGTCTTTTACAGTTCAGATAAATTTTAGGGTTGTTTTTTCTATTTCTGTAAAGAATATTATTGGTATTTTCATAGGGGTTGCATGACTCTGTAGATCACTTTGGTAAGCACAGACATTTTAGCAGTATTCATTCTTCCAATCCATGAACACAGGATATCTTTCCATTTTTTTGTGTCCTCTTCAATTTATTTCATCAATGTTTTATAGCTGTCATTGCAGTACTCTTTCACTTCTTTGGTTAAATTTATTCATTTGTTTTTATTTTTTGTAACTATTATAAATGGGATTGCTTTCTTGATTTCTTTTTCTGATTGTTTGCTGTTAGCGTATAGAAATGCTACTACTTTTTCTACATTGATTTTGTATCCTACAGCTTTACTGAATTTGTTTATAACCAGTGTTTTCTTTAGGTTTTTCTAAATATAGGATTATGTCATCTGTGAACATGGATAATTTGAGTTCTTCTTTTGCAATTTGGATGCCCTTTATTTCTTTCTCCTGCCTAATTGCTCTGGCCAGGACTTCCAGTATTACCTTGAATAAAAATAGTGAAAGTGAGCATCCTTGTCTTGTTCCAGATCTTAGAGGAAAGGCTTTCAACTTTTCCCCATTCAATATGATGTTAGCTGTGGGTTTGTCATATATGGCTTTTATTATTTTGAGATATAGAACCACAGCTTTTTTTTTTTGAGACAGAGTCTTGCTCTGTCACTCAGGCTGGAATGTAGTGGTGCAATCTCAGCTCACTGCAACCTCTACCTCCCGGGCTCAAGCAATTCACCTGCCTCAGCCTCCCCAGTAGCTGGGATTACAGGTGCCTGCCACCACACCTAGCTAATTTTGTGTATGTGTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAAATCCTGACCTCAAGTGATCCACCCGCCTTGACCTCCCAAACTGCTGGGATTACAGGCGTGAGCCACCGTGCCCGGCCAGAACCACAACTTTTGATAGAAGGCTCAAGACAGATACCCTAACCTACCCTCTTTTTTCACTTTTTTATTTTATTTTTTAACCTTTTATTATGAACATTTTCAAACATAAACAAAAGCAGTATACTGATCAGTAGTAAACCTCTGGGCACCCATTACTCAGCTTTACTTATTCTTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGCATCTCACTCTGTTGCCCCGGCTAGAGTACAGTGGCGCGATCTCGGTTCACTGCAACCTCCGCCTCCCGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGGACATGCCACCATGCCCGGCTAATTTTTGTATTTATAGTAGAGATGGAGTTTCACCATATTGGCCAGGCTGGTCTCGAACTCCTGACCTCGTGATCTGCCCACCTCAGCCTACCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCACCCGGCTATTTACTTCTTCTTTTATGAAGCTCCCTCCTCCAAAACACCCCCATCACCTGTTCCTTCCAGCTCTCTGACCACTCCTTGGATTCTCTGTGAATTCCCTTTTCTCTCTTTGAAGCCTGCCTTCCTGGTACTGTACTCTTGCACACTCTCTTTCCTCTTGCAAGAAGCCAGCACGTGGTACAGATCTTGCCAATGACCCTTCTCTCACTAGCTGAGTGGCATGAAGAAGCAGAAAATGGTTAAGAGCATTGGTTTGGAGTCACAGACCTTCATTGATTCCCAGCTCTGCCACCTATAGCTATTTGACTTGCACAAGTCACTAACCTTTCAGAGACTCAGCTTCCTTACGTGCAAAGTAAAAATCGAATGAGATAACCCAAATAAAATGTCATTAGGGGGATTTTTAGGTTATGTATATAAATCATGCAATAAATGCTAGTCATTTCTTTCCTCTGGTTGACTGAGAGCTTCCAGGAAATAGGAATGGGTTCTAACTTTCTTTGTATTCCTAGTGCCTAAAACGGTGCCTGACACAAAGTAGGCACTCAATAGATGCTTATGAATTAATAAAGTATGAGAGAGCCTGGTAGGTATTTAGCAGGGGAGGAAGGTTTTACCAAAAATGGTGCTGTGTTTGGTGGCAGTGTGTCATAGAGATTGTTTGGGACTGGGGAAGTTTGAGTTGTGTGTCGCCAACAATTGTGTCTCATGGGGAGTTGAGATAGAAGGATTGTGACACATGGCCATGATGGATGGTGAGTTGAGTGATGCTGTTGAGCTGGAAGGTGGGGGACTGGACAGACTATCTTGAGCTGGGTCCCTTGTAGTGCTGGGTTGGGCTCATCCACTGGTTCCCTGTCTAATCCTCTTTGTCTGCAG
Seq C2 exon
TGTGCCCCAGGCTACGATGGACAGAACTGCTCAAAGGAACTCGATGCTTGTCAGTCCCAACCCTGTCACAACCATGGAACCTGTACTCCCAAACCTGGAGGATTCCACTGTGCCTGCCCTCCAGGCTTTGTGGGGCTACGCTGTGAGGGAGACGTGGACGAGTGTCTGGACCAGCCCTGCCACCCCACAGGCACTGCAGCCTGCCACTCTCTGGCCAATGCCTTCTACTGCCAGTGTCTGCCTGGACACACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000204301:ENST00000375023:18
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0000822=EGF=WD(100=48.4),PF0000822=EGF=PU(71.4=40.3)
A:
NA
C2:
PF0000822=EGF=PD(22.9=9.4),PF0000822=EGF=WD(100=36.5)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains