HsaINT1025135 @ hg38
Intron Retention
Gene
ENSG00000204301 | NOTCH4
Description
notch 4 [Source:HGNC Symbol;Acc:HGNC:7884]
Coordinates
chr6:32196324-32197072:-
Coord C1 exon
chr6:32196925-32197072
Coord A exon
chr6:32196422-32196924
Coord C2 exon
chr6:32196324-32196421
Length
503 bp
Sequences
Splice sites
5' ss Seq
GGGGTATGT
5' ss Score
7.48
3' ss Seq
CCTCCCACGTCGTCCCCTAGGGA
3' ss Score
8.62
Exon sequences
Seq C1 exon
CTTCTGCTCCGTAGCAGACAAACTGCAGTGGACGCTCGCACAGAGGACGGGACCACACCCTTGATGCTGGCTGCCAGGCTGGCGGTGGAAGACCTGGTTGAAGAACTGATTGCAGCCCAAGCAGACGTGGGGGCCAGAGATAAATGGG
Seq A exon
GTATGTAGAGGAAGGGGTGATGTATGCTATAGAGAAGTTGAGCAGATGGGGTGGGAGATAGCGTGCAAAATATAGGTGCAGCAGAGGGGCATTCCCTCTCATCCTGCTGTTACGGCGGTCAATCTGAGATGCGGTGGAAGTACGGGCCGCGTGAGTTTCCCCCCCCAACTCCCACCCTCAACACCACACTGGCCCTCCGCTCCAGCTTACTGGGGAACTGGCATGGAACACAGTGTCTGTGGAAAGGGGGGGGAATCTCGTGGGGGGAGACTGTCTCCCGGTCTCACCGACCCCAGAACAATGCCCCATTGTCCCTCCCGCGCACTGGTGACGTCACCAGGGCAACACTTCCTGCAGGCCGGTGGTCTCCTGGGCAACGCTTCCCGCCTTTGAGGGACCAGCCGGCCCGAATAGCCCTTCCCCCAAGGCCAGAACCCGTGGGAAACCGGAACCCAGGCGTCTGGCCCCCAACTGGGGTAACAACCTCCCACGTCGTCCCCTAG
Seq C2 exon
GGAAAACTGCGCTGCACTGGGCTGCTGCCGTGAACAACGCCCGAGCCGCCCGCTCGCTTCTCCAGGCCGGAGCCGATAAAGATGCCCAGGACAACAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000204301:ENST00000375023:28
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.140 A=NA C2=0.424
Domain overlap (PFAM):
C1:
PF127962=Ank_2=PD(14.0=26.0),PF127962=Ank_2=PU(58.7=88.0)
A:
NA
C2:
PF127962=Ank_2=PD(40.0=90.9),PF127962=Ank_2=PU(6.2=12.1)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GACAAACTGCAGTGGACGCTC
R:
CCTGTTGTCCTGGGCATCTTT
Band lengths:
230-733
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains