HsaINT1025136 @ hg38
Intron Retention
Gene
ENSG00000204301 | NOTCH4
Description
notch 4 [Source:HGNC Symbol;Acc:HGNC:7884]
Coordinates
chr6:32194843-32196421:-
Coord C1 exon
chr6:32196324-32196421
Coord A exon
chr6:32196151-32196323
Coord C2 exon
chr6:32194843-32196150
Length
173 bp
Sequences
Splice sites
5' ss Seq
AGGGTTAGA
5' ss Score
1.78
3' ss Seq
GCCCTGGCTCTTCTGTACAGGAG
3' ss Score
7.75
Exon sequences
Seq C1 exon
GGAAAACTGCGCTGCACTGGGCTGCTGCCGTGAACAACGCCCGAGCCGCCCGCTCGCTTCTCCAGGCCGGAGCCGATAAAGATGCCCAGGACAACAGG
Seq A exon
GTTAGATGGGACAGAGGGCTTCCCACAAAACAGTCAGGCGCACGAGAGATGGAAAGTGCGGTAACCCGCAAAGCCTGAAGGGATAGGGGCCAGTGGTCGCGCAAGTGAAGGCAGAAAGGCCCAGTCCTGTGGGCGTGGCCTTCCCTGATATCGGCCCTGGCTCTTCTGTACAG
Seq C2 exon
GAGCAGACGCCGCTATTCCTGGCGGCGCGGGAAGGAGCGGTGGAAGTAGCCCAGCTACTGCTGGGGCTGGGGGCAGCCCGAGAGCTGCGGGACCAGGCTGGGCTAGCGCCGGCGGACGTCGCTCACCAACGTAACCACTGGGATCTGCTGACGCTGCTGGAAGGGGCTGGGCCACCAGAGGCCCGTCACAAAGCCACGCCGGGCCGCGAGGCTGGGCCCTTCCCGCGCGCACGGACGGTGTCAGTAAGCGTGCCCCCGCATGGGGGCGGGGCTCTGCCGCGCTGCCGGACGCTGTCAGCCGGAGCAGGCCCTCGTGGGGGCGGAGCTTGTCTGCAGGCTCGGACTTGGTCCGTAGACTTGGCTGCGCGGGGGGGCGGGGCCTATTCTCATTGCCGGAGCCTCTCGGGAGTAGGAGCAGGAGGAGGCCCGACCCCTCGCGGCCGTAGGTTTTCTGCAGGCATGCGCGGGCCTCGGCCCAACCCTGCGATAATGCGAGGAAGATACGGAGTGGCTGCCGGGCGCGGAGGCAGGGTCTCAACGGATGACTGGCCCTGTGATTGGGTGGCCCTGGGAGCTTGCGGTTCTGCCTCCAACATTCCGATCCCGCCTCCTTGCCTTACTCCGTCCCCGGAGCGGGGATCACCTCAACTTGACTGTGGTCCCCCAGCCCTCCAAGAAATGCCCATAAACCAAGGAGGAGAGGGTAAAAAATAGAAGAATACATGGTAGGGAGGAATTCCAAAAATGATTACCCATTAAAAGGCAGGCTGGAAGGCCTTCCTGGTTTTAAGATGGATCCCCCAAAATGAAGGGTTGTGAGTTTAGTTTCTCTCCTAAAATGAATGTATGCCCACCAGAGCAGACATCTTCCACGTGGAGAAGCTGCAGCTCTGGAAAGAGGGTTTAAGATGCTAGGATGAGGCAGGCCCAGTCCTCCTCCAGAAAATAAGACAGGCCACAGGAGGGCAGAGTGGAGTGGAAATACCCCTAAGTTGGAACCAAGAATTGCAGGCATATGGGATGTAAGATGTTCTTTCCTATATATGGTTTCCAAAGGGTGCCCCTATGATCCATTGTCCCCACTGCCCACAAATGGCTGACAAATATTTATTGGGCACCTACTATGTGCCAGGCACTGTGTAGGTGCTGAAAAGTGGCCAAGGGCCACCCCCGCTGATGACTCCTTGCATTCCCTCCCCTCACAACAAAGAACTCCACTGTGGGGATGAAGCGCTTCTTCTAGCCACTGCTATCGCTATTTAAGAACCCTAAATCTGTCACCCATAATAAAGCTGATTTGAAGTGTTA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000204301:ENST00000375023:29
Average complexity
IR
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.424 A=NA C2=0.591
Domain overlap (PFAM):
C1:
PF127962=Ank_2=PD(40.0=90.9),PF127962=Ank_2=PU(6.2=12.1)
A:
NA
C2:
PF127962=Ank_2=PD(90.6=24.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAAAACTGCGCTGCACTGG
R:
AGCAGATCCCAGTGGTTACGT
Band lengths:
246-419
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains