HsaINT1027366 @ hg38
Intron Retention
Gene
ENSG00000225190 | PLEKHM1
Description
pleckstrin homology and RUN domain containing M1 [Source:HGNC Symbol;Acc:HGNC:29017]
Coordinates
chr17:45458169-45468593:-
Coord C1 exon
chr17:45468209-45468593
Coord A exon
chr17:45458440-45468208
Coord C2 exon
chr17:45458169-45458439
Length
9769 bp
Sequences
Splice sites
5' ss Seq
CCGGTGAGT
5' ss Score
10.9
3' ss Seq
GTTGTCTTCTTTCCCAACAGAAA
3' ss Score
11.09
Exon sequences
Seq C1 exon
GGTATTGTTGGAATTCAGCAAAGCCCAGGTAAACTCTGTGCCAACCAACGGACTGAGCCAAGAAACAGAGATCCCCACACCACAGGCCTCGCTCTCCCTCCATGGCCTCAACACCAGCACATACCTGCACTGTGAGGCACCTGCAGAGCCCCTTCCTGCCCAGGCAGCCTCTGGAACTCAAGATGGTGTCCACGTGCAGGAGCCGCGTCCCCAGGCGCCCAGCCCCCTGGACTTACAGCAGCCTGTAGAGAGCACCTCAGGCCAGCAGCCTTCTAGTACTGTCAGCGAGACAGCCAGAGAAGTGGGCCAAGGGAATGGCCTGCAGAAGGCCCAGGCTCATGACGGAGCTGGTCTGAAGCTGGTAGTTTCCTCACCCACCAGTCCG
Seq A exon
GTGAGTGGTGCAAGCCGTTCAGGGGGCAGTCTTGGGAAATGTCAGCTGACACAGGGTTTCCCCAGCTAGTGACCCTGAGTGGTCTCTGCCTTTTCCCTGTTAGCCTTCCTCTCCCTGCATAGTGATAGTGTTAATAGCATCATGATGATGGGGCTCATGTTTCTTGGCATGTGAGCTGTAGATATAAGCCCGGCTGTTTCTTGGCATGTGAGCTGTAGATATAAGCCCGGCACTGTGCTGATCACTTCCCGTGTGTATCTCCTGTCATTTTCACGTCACTTTGTGAAGGTTGTTCTTGTCTGACCGCAGTCTCAGCTCTTTAACCACTACCACTCACCAGCATAAGGCCTTGGGCAAGTCACTTCAGCTCTCTGAACCTTCATTTCCTCCTTAGTACTTGTTATTATTAAATTAATATTTTTTGATTTTTGGTTTTTGGTATTTTTTTCAGATGGAGTCTTGCTCTGTTGCCCAGGCTGGAGTGCAGTGGCACAATCTCTGCTCACTGCCACCTTCGCCTCCTGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGTGCCCACCTCCATGTCTGGCTAAGTTTTGTGTTTTTAGTAGAGATGGGGTTTCATCATGTTGGCCAGGCTGGTCTCGATCTTCTTGCCTGGGCCTCCTGAAGTGCTGGGATTACAGGCATGAGCTGGTGCACTCAGCCTATTAAATTAATGTTTTTAGAAAATACTAGGCCTTGAGCATACTCACTTTGCAACATGACCCAGGTTTTAGAGCCGTGCTGTCCAATATGGCAGCTACAAGCCACGTGTGGCTGTTGAACACTTAAAATGTGGCAAGTCCAAATGGAGATGTGCCATGTGAAATAAGCGCTGGATTTCAATAACTTAGTATGATAAAAGAATAGAAAATCTCATTTTTATGGATTACAAGTTAAAATGAAAATATTTGGGGGCTGGGTGTGGTGGCTCACACCTGTAACCCCAGCGCTTTGGGAGACCAAGAGGGAGGACTGCTTGAGCCCAGGAGTTGGAGACCAACCTGGGTAACAAAGTGAGACCCCATCTGTACAAAAAATACAAAAATTAGCTGGGCATGGTGGTGTGTGGCTGTACATATAGCATGAGGCTGTAGTTAATTCTTTTCCATTGTTCTGCAGTATTCCATTGTAAAAATATATTGCAACCTATTACCCATTCTCCTGTTAATGGACATTTGGGTTGTTTCCAGGTTTTGACTATTATGAAGAAAGCTGTAGTGAACATTCTCATACATGCTTTTGGAGAACCTCGGTGCTTATTTCTGTGGGTATATATACCTGGGAATGGAATTGCTAGGTCCTTGGGTGGCTTATGTTTACCTTTAATAGATACCACCACCAAACAGTTTTCTAAAGTGTTTGTGCTAATTTATACTCATATTGGCAACAAATGAGCATTCTAGTTGCTCTTTATCCTGGCCAATGGTGTTACCAATCTTTTTAATTTTAGCCACTCTGGTAGATGTGTAGTGGTTTTAATTTTCATATCCTTGATGACTAAATGATGATACCTTTTCATTTGCTTATTGGCCAGTCAATCCTCTTTTATAGAATGTCTGTCCAAGTTGTCATTCCGGTCTTAAATTGAGTTGTATGTGTATGTGTTGATTTGTAGGAACTCTTTATATATTACAGATATAAGTCTTTTATTGGACAAAAATAGTATATTTATCAAGTATCTTTTTCTAGTCTATAAGGCTTGACTTTTAAACCTCCTAATAGTATTTTTATTGAACAGAGGTTCTTTTAATGATGTGCAGTTTATCAGTCTTTTTGTTTATGGTTTGCTTGGTTTTTGTCCCATTTAAGAGATATTCATCTCCCCCAAGGATCTGAAGGTATTTGCCTATATTATCTTCTAGAAGCTTTAGTGATTTATCTTTCAAAATTAGGTTTATGATCTTTCTGGGATTAATTTTTGTGTGTGGTGTTAGAAGTCAAACCTCATATTTTTCCATATGGATATCTGATTGGCCTCACTGTTTCTTGAATATGACCATGTAAATCACAAAACTGTCAGTGTGGGTCAGAGTCTTCGAATTTGCTATCCTGAAGATGCTTCAGTACATCCTGAAGATTTGCTTCCTGAAAATGAATGCTCTAGGACCCTGAAGGTTGTGACTGTGCACCTGCCAACTCAAGCTGAAGGCTGAAGAGGAAAGCTCTGCAGCCCCTTCCTCAAGCTGGAGGCAGAGTGACGTCTGCTGGGGATGCAGGCTGTGCGCCCCACAGGACTCCAGAGTGGCACTAAGCATGTTGAGTTCACTCCTGCCCATGGTCTAGCTTCTGCTTTGCAGGCTCAGGCATCTTATCTTGCCAGGGCCTCAAAGCTGGTGGGACAGAATAGCATCTTTGCTCACTAAGCTCTGACCCACCGGCCTCCTTGCAGCTCTATAGTCCAAGCGAACTCCTTCCAACATCAGGCTTCTTTTAAAAAAAAAAATTTTTTTGAGGCAGAGTCTCACTCTGTCACCCAGGCTGAAGTACAGTGGTGCAATCTCAGCTCACTGAAACCTCCGCCTCCTAAGTTCAACTGATTCTCATGCCTCAGCCTCCCAAGTAGCTGGGATTACAGATGCCTACCACCATGCCCAGCTAATTTTTGTATTTTTACAAAATTATGGGGTTTCACCATGTTGACCAGGCTGGTCTCAAACTCCTGGCCTCAAGTGATCTGCCCACTTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGTGCCCGGCCCAGCCTCAGGGTTTTACATTTGCTGTTCCTTCTTTCCCGACTCACTTCATTGTTGTCTCAGCCTTCCCTGACCGGACCCCCGTAGCTCAAAAGCACCATCCCCAGTGACTCTCTGTCCCATTCATCTGCTTGACTTTGCTTATAACACTCATCACTATGTGCAATTACAGTATATTATCTCTTTGTCTCCTTGTTTATTTTCTGTCTTCCTTACTAGAATATTAGCTCTATGATACAGAGCACCAGGCCTGTTCACTTCTGTATTGTCAGCACCAAGCACTGTACCTGGGAGAAAGTAGGCATGGATGAATAGTTCTTGAACTCCCAAGAGACTCTTGAGATGCCAATTCCTAAGTTTATTTTGTTCCCCCATCCTAGCTATAAGGCTGTTTGGAATGGTTCTTTTTCTTGGTATCTCCAGCAAGTACCTGGCCCAGAATCATACAAGATGTGTGAATAAATCATGACCATCCCAATGTCTTTAATATAAAGTAACAAAGATAAGTCAAGGGGACTGGAAGGAAGGAGACAAATGTGAAACTTAAGATTATGGACGTTCAGGCGAGGCGTGATAGCTCACGCCTCTAATCCTAGCAATTTGGGAGGCCAAAGTGGGTCATCGAAGTGTACCATCGAGTGGACAGGGTGGTCAGGTTGGTGTGATCATGGCAGGCTCTGCCTCTGTGCCAGCTACAGGGGACTCTGATTGCTGGAAGGTTGCTTAGGGAATGTGACATCTAAGCGCTTGGTGCTGAATCCGATGTGAGAATCTCGGATCCTGCCCCCGTCCTGTGTCTGTCTCACAGGGAAGTTGTGGATTCATTCACTGCTTATTCAGTAGGTAGTCACCAGGTGCCACTGAATAGCCTGCCAGCTCATGTGGGCCTGCTGGGCTCCTGGCCTGTGGACAGTGCCAGGCTGTGCCCTGCATGTCTGCCCCTGTGGTCCTCATCTTTCTGTACTTCTATCAGTTAGCCACGTGCTTTTTATTTGATGTTATTTTGGGGGAGATGTTGGGGTCGCTGTCAAGTTTTATAGTGTAGAGACCCATTCAGTCTTTCTTTTAAAAACATTTATTTTTAATTCATTGAACCCAAAGCACCTACTATAAGCCAAGCACCATGTTAGGTCCTAGGGGTAGAGTGATACAACAGGACAGACAAAGGCCCTTTGGGGACAGACATTAAATTAGACAAATGATTATCCACATCATAATTACACTTGTGCTAAGCACTGGGAAGGAGAGGTGCAGGGAGTAGGGGCCTCTCAAGGGTGATGCATGTCTGGGATCTGGGGGTTGTGAGTTCGTTTCAGTTTAACTCCCAAAAGGCAGTGTGAGTTCTAGGACTTGCTCTTAATCACTGCCCCCATGGACCACCTGCCCATGGTATGTGGTTCCCCTTCCACAGTTATGAGTACAGGCAGTTCCTTTGCCTGGCATAATGAGGACTGGCTGGACAAAGTCTCATCCTTCTGAAAGTGTCCCAGAGACCTTCGTCTCACTCCTCAGCCACACTCCTCTTGGGGATTCAGCTGTTGTATATGGTGTCATGAGCCCTTTAGTAACGCAAGGTGGCATTTCTCTGTCTTGGGTCGCTGGTGGCAGTTGCAGCTCTGGTATAGATCCTTCGTCGATGATGGTTTCTCTCCACTGTTAAAGGGCGGGGTGCTGGCCAGACATGGACCCTGAGTGAGCAGGTTGTCGGAAGGTGGTGGGAAAAAAGGAGAGAAGGGGGCCGGGTGCAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGTGGATCACCTGAAGTCGGGAGTTTGAGACCAGCCTGACCAATATGGTGAAACCCCGTCTGTACTAAAAATACAAAAATTAGCCGGGCATGATGGCGTGAGCCTGTTATCCCAGCTACTCAGGAGGCTGAGGTAGGAGAATCACTTGAAACTGGGAGGCAAATGTTGCAGTGAGCCGAGATCACACCACTGTGATCCAGCCTGGGCAACAGAGTAAGACTCCATCTCTAAAAGAAAAAAAGGAGAGAAGAGAGAAACAGTGGTGTTCATGCATGCACTCTCTCTCACACCCTCTCTCTGCTCCCCACCTGCCTGGGGCCAGGGGCACACAGCCTCAGAGCTCTGTCCAGGCCCATGTGCAGAAGCTCCGAGGAACCTGCATTTCCACTGTTTTTTCCCTGTTGCTTAAGAGAGTAAAAGATGTTCCCTAGTTTCATTTCCTGGCAGCTGTGCTCAATGGACTGTGTCTGAACATTTCCTAGTAGTCTTTTTCCTCAAAGGAGAGAGAAGTCCTCCCCAGTGAATGTCCATATACTTTTTTTTTTTTTTTTTTGACACAGACTCTTGTGCTGTTGCCCAGGTGGGAGTGCAATAGCTCCATCCATCTCGGCTCACTGCAACCTCTGCCTCCAAGGCTCAAGCAATTCTTGTGCCTCAGCCTCCCGAGTAGCTGAGATTACAGGCATGCACCACCATGCCCAGCTAATTTTTGTACTTTTAGTAGAGATGGGGTTTCTCCATGTTGGCCAGGCTGGTCTCAAACTTCTGGCCTCAAGCAATTTTCCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGATCCATCATGCCCATTCTGAATGTCCATAATCTTAAAATTTACATTTGTCTCCTTCCTTCCAGTCCACTTGACCCACCTTTGTTATTTTATGTTAAAGACATTGTGATGGTCATGATTTATTCCCTCATCTTGTATGACTCGGGCAGGCACTTGCTGGAGATATCAAGAAAACCATTCCAAACAGCCTTATAAATGCTAGAATGAGGGTAAGCACAGAATATTGTGGGATCCCAGTAGGGGCCCTAACCCAGCTAGGGGGTGGGAAGGGGTGGAGGCTGGGGAAGGGTGAGAGAAGCTTCCAGGCAGAGGCGATGGATGTCTCCTGAGCTGAGTCTTCAGGGACAGTGCCCTCTCCCACCAGGCGCTGGAGATCACACAACTTCCCAGGTATATGTGAGGCTGCCAGGACAGCCACATGGTTGCCAGGGAGCTGTTTCTCCCACCCATTTTCCTCAGGGGGGTCCCCCAGTTCTTGATGACCTAGGCAGGCTTTGCTCAGAATCTAGTGTTGTGGATGGTCCCCAGTGGCTGCCCTGACTGACACATCATCTGTCACTGGCAGGGGGGAAGCACCTGCCAATTCTGAAGGCCCCGTGGAGGAGTCTCTGGGGACCTAGTTCTGTGAGCTACCCCTCAAGTTGCCTGAGTCAGAACTTGCCACCCTTGGCTTGAGGAGTCGTGTAGCATCTGAATGGATCCAACTGTCCAAACCAACCCTTCCCTGTTTACAAAGCAGGGAGTGCAGTCTTGATTCAGGGACTGGAAATAGCGATGTCAGGGTGAGGTTAGTGGCACTTAACAAAACAGTGGGGCTGGTCCCACTGCTTGTGTGACTCATTTCCTCTGTGTACACAGCCACTTAGAGTGGCCCAGCCAGCTTCCTTGCCTCTGCCCTTCCATGTTGAGGCACAGAATGCCAGGGAGGACTTGAAATACTGGAGAAAAGGAACCAGAATCCACTCCCACAAGCCCACTCACCCCAGATGCTCCCCGCAACCCCATCTTCCCCAGCCAGTGAGCAGCTTCAGATTCAAAAGAGAACAACGAAGGGAAGGGGCAGGGCCTGGCTGCCTGGGGTTGCAGGGGCCTGCACAGAAGTGGGCGGCAGAGACAGAGGCGGCCAATGAGGACCCTGAGGCCTGCTCGCCAGGACTCCCTCATCTCAAACCCAAAAGCAGGACTGAGAAACCCTACATGCTGGGACAGCTGAATACCCACATGCAAAATAATAACACCCCTTCCTTACACCTTACACAAAAACTAACTCAAAATGGACCAGAAACCTAAATGTAAGAGCTAAAACTATACAGCTCTTGGCAGAAAACACAGAAGTAAATCTGTGATACTGACTTAGGCAATGGTTTTTTAAGATGCAACACCAGAAGCACAAAAACAACAACAAAAATAGATAAACTAGACTTTATCAAAACTAACAACTTATGTGCTCCAGAGGGCACACCATCCGGAAAATGAAAAGACACCTCACAGAATGGGAGAAATTATTTGCAAATCGTAAATCTGATAAGGGTCTCGTATTCAGAATATATAAAGCACCTTACAACTTGAATTAGTCCCTAGGGCCACCATAACAAAGTACCATACACAGGGTGGTTTAAAACAACAGACATTGGCTGGGCGCGGTCGCTCATGCCTGCAATCCCAGCACTTTGGGAGGCCGAGGCGGGTGGATCATGAGGTCAGGAGATCGAGACCATCCTGGCTAACATGGTGAAACACCGTCTCTACTAAAAATACAAAACAAAATTAGCCAGGCGTGGTGGCAGGCACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATGGCGTGAACCCGGGAAGCGGAGCTTGCAGTGAGCCAGGATTGTGCCACTGCACTCCAGCCTGGGCGACAGAGCAAGACTCTGTCTCAACAACAATAACAACAACAACAAAACAAAAAACAAAAACAGACATTGCTGGGCAGGTGGCTCATGCCTGTGACCTCAGCACTTTGGGAGGCAAGGGTGGGCGGATCACTTGAGTCCAGGAGTGCAAGACCAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATATAAAAAATTTGCTGGGCATGCTGGTGCATGCCTGTAGTCTCAGCTATTCAGTGGGGCTAAAGCAGGAGGATTGCTTGAGCCTGGGCAGTCAAGGCTGCAATGAGCCCTGATTGCGCCACTGTACTCCAGTCTGGGCAAAGAGCGAGACCCTGCCTCAAAACAAAACAAAACAAAATAGGCCAGGCACAGTGGCTCACGCCTGTAATCCCAGCACTTTGGAAGGCTGAGGCAAGTGGGTCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCGACAAGGTTTTGTCTCTACTAGAAATACAAAAATTAGCCGGGCATGGTGGCAAGCATCTGTAACCCCAGCTACTCGGGAGGCCGAGGCAGCAGAATTGCTTGAACCTGGGAGGCGGGGGTTGCAGTGAGCTGAGATTGCACCATTGCACTCCAGCCTGGGTGACAGAGTGAGGTTCTGTCTCAAAAACAAAACAAAACTGGTATTTATTCTCTGATCGTTCTGGAGGCTCCTTCTGGAGAATCTAAGGAAGAATCTGTTCCCGCCTTTCTCCTGGGTGGCGTTGCAGGTGCTCGTTTGCATTCCTTGGCTTGTAGACATGTCACTCCTGTCTCCCCTCTGCTGTCACACATGTTCTACTGTCATACAAGTTCTTCCTCTGTATCTCTGTCTTCACTTGGTGTTCTCCTCTCTTTGTGTATCTTTTCTCCTCCTCTTATAAGGACATCAGTCATACTGGATGAACAGCCCATTCTACTCCAACATGACCTCATCTTAACTAATTACTTCTGCAAAGACTCTATTTCCAAAAAAGGTCACATTCTGAGGTACTGGGGGGTAGGGTTTCAACATGTCCTTTTGTGGGGGGGTCACAATTCAACCCACAACACAACTCAGCAACAAAAAGACAGCCCCATTTTAAGACAGACAATGGATTTCAGTAGATTCCAATGGATTTGGATAGATTTCCCAAGGAGAGAAATTGGAACCCTCGTACATTGCTGGTGGGAATATAAAATGGTGCGGCCACTTTGGAAAACAGCTTGGTAGTTCCTCAAGAAGGGAAACATAGAGTTACACATGACCCAGCAAGTCTACTCCTAAGTATATACCCAAGACAATGAAACATGTCTACACAAAAACTTGTGTATAAGTGATCATAGCAGCACTATTCATAATTGACAAAAAGTAGAAACAACCCAAATGTCCATCAGCCGAGGAGTGGATAAGCCAAATGTGGTGGATCGAGACAATGGAATATTATTTGGCAATAAAAAGGAATGAACACTTAAACATGCTTATATAACATGGATGCACCTGGAAAACCTCCCACTAAGAGAAAGAAGCAGGCACAAAAGGTCACGTGTCGTATGGTTCCATCTATATGAGATGTCCAGAACAGGCAGGTGTGTAGGGACTGAAAGTAGGTAAGTAGGTGCCTAGAGCTGAGAGTGGCCAGGGGAAATGGGGATGACGGCTAATGGGTACGGGGTTTCCTTTTTGGGTGAGGAAAATTTGCTAAACTTAGATGGTGGTGACGATTGCCCAACTCTGACTAAGCCAAAATGTTTGAATTGGACACTTTATTTATTTATTTTTTTAGAGATGGGGTCTCATTCTGTTGCCTAGGCTGCAACCAGGCTGGAGGGCAGTGGCGTGATCACGGCTCACTGCAGCCTTGACCTCCCTGGCTCAAGCGATTCTCCCGCTTCAGCCTCCTCAGTAGCTGAGACTACAGGTGTGTGCCATCACACCCAGCTAGTTATTTTTTGTAGAGATGGGTTCTCACTGTGTTGCCCAGGTTGGTCTCAAACTCCTGGGCTCAGGTGATCCTCTCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCATGGCTGGCCGAATTACATACTTTAAGTGGGTTAATTTTATGATATAAGAGCCATATCTAGATAAAGACTTAAAAAAAAAAAAAACTTCAGGCTGGGCACAGTGACTCACACCTGTAATCCCAACACTTTGGGAGGCCGAGGTGGGTGGCTCACCTGAAGTCAGGAGTTCTAGACCAGCCTGGCCAACATGGTGAAACCCCGCCTCTACTAAAAATACAAAAATTAGCTGGGCATGGTGGTGGGCGCCTGTAATCCCAGCTACTCAGGAGACTGGGGCAGGAGAATCGCTTGAACCCAGGAGTCAGAGGTTGCAGTGAGCCGAGGTTGCGCGATTGCACTCCAGCCTGGGCAACAGAGCGAGACTCCGTCTCAAAACAAAAAAACTTTAAAACAAACAACTGTTGTCTTCTTTCCCAACAG
Seq C2 exon
AAAAACAAGAGCTGGATCTCAGAGGATGACTTCTACCGGCCTTCCCGGGAGCAACCCCTGGAGAGTGCTTCAGACCACCCAATAGCTTCTTACAGGGGGACTCCAGGGTCAAGGCCTGGTCTCCACAGGCATTTTTCTCAAGAACCAAGAAAAAACTGCTCCCTGGGGGCGTTAGACCAAGCGTGTGTACCTTCCCCAGGAAGAAGGCAAGCCCAGGCAGCCCCATCCCAGGGGCATAAGAGCTTCCGGGTGGTACACCGGAGACAGATGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000225190:ENST00000430334:5
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.961 A=NA C2=0.857
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains