HsaINT1028635 @ hg38
Intron Retention
Gene
ENSG00000126838 | PZP
Description
PZP, alpha-2-macroglobulin like [Source:HGNC Symbol;Acc:HGNC:9750]
Coordinates
chr12:9153125-9154839:-
Coord C1 exon
chr12:9154616-9154839
Coord A exon
chr12:9153344-9154615
Coord C2 exon
chr12:9153125-9153343
Length
1272 bp
Sequences
Splice sites
5' ss Seq
CAGGTCAGT
5' ss Score
8.94
3' ss Seq
TGTCCACTCGTCTCTTCCAGGAC
3' ss Score
12.09
Exon sequences
Seq C1 exon
ACAACCTCGTCCATTGGGAGCGCCCTCAGAGACCCAAGGCACCAGTGGGGCATCTTTACCAAACCCAGGCTCCCTCTGCTGAGGTGGAGATGACATCCTATGTGCTCCTCGCTTATCTCACGGCCCAGCCAGCCCCCACCTCAGGGGACCTGACCTCTGCAACTAACATTGTGAAGTGGATCATGAAGCAGCAGAACGCCCAAGGTGGTTTCTCCTCCACCCAG
Seq A exon
GTCAGTGGTTCCCAAAGAGTCTTCTGCTCCAGGTTCACTTGGCAATTGGGAGGCTTAAAAGTAGAACAGTTAATGGAAAAGAGAAGGCAATTATTAAATCATTGAAGAAGTATTTAGGAATATTTGAGGACCATGAGAATTTAAAGGAAAGACTTAAGACATCCCCCATAACACTTTTCACTAAGCCCTATGTTAATATATTAGCAACATGGAGACGTACAACGAGCATCTTTACCCTCTAAAGCCACGCTATGGTCATTGGACACATTCTAGACCAGAGTTTTTCAGCATCAACACTATTGACATTTCGAGCCACATCATCGTTGTAAAAGGAACTATCCTCAGCCTTATAAAATATTCAATAGTATCCCTGGCCTCTCCCCATTAGATGCCAGTAGCACGTCACTTCCAGTTGAAACAAGAAAAAATTTCCTCCAGTTGGGAACCAATGTTCCAGACATCTTCAGAATCTAACAAGAAATCCTCTAAGATGTATTCCCCAAAAAATGTGTGATTAAAAGTACAGTGACTAAGTAGAATCCACTTTGATCTTTTTGGAATGAGAAGTTCCATTTCAACTACTCCAAGGAACTCAGCTTCTTCATTCCTTTCTACTTTCCCTGAGAGTGCTCTTCTTACTTTCTCTTTAAGTTGATCTTTTTTAAGCTGAAGCTCTTGAAAATGTATTTTTCTAGCATAATTCTAAAAGTATTTTATCGAGAGTATAAATGATTGTATTAAACACCCAGAGTGTCTGGCTTTTCCCTCCTACATGTCTTCTTTCAACAGTTAGGATCTCCATAGTGAAACTTTTGTTTTTCAGAGAGATTAGGTGGGGTAAATAAAAACAAGCTAGATGAAGGTAAAAAGAAACTCAAGAAAGTGCAACTTGTCTCATACCATTTTCATGTACAGTAAATTTTTATCACTCTTCCATCTAACTGGTCAATCATCTACTTAAAAATGGTCACTATTTTTGTCTTAACTTCTTAGTTTTAGACCTATTCTTTGAAGGACATATCCAAAAGGACTGTCAATGAAAATAAACAGTGACATTAATAAACATTATTAGCCTTTTATTTCATTTGGAGAAACTGCAGCATGATTTTGATAATGTCTGAAAGGCAGAGAAAAAGGAAAGGTAATTAGTGAAGATCTACCTTAGGGGTAAAAAGCCAGCTTCCCTCATGGTAGGCTAACACAGACTTTGGGGGAAAATCCCAGATGCCAAAAATTTACTCTTTGGGGCGGTTGTCCACTCGTCTCTTCCAG
Seq C2 exon
GACACAGTGGTGGCTCTCCATGCCCTGTCCAGGTATGGAGCAGCCACTTTCACCAGAACTGAGAAAACTGCACAGGTCACCGTTCAGGATTCACAGACCTTTTCTACAAATTTCCAAGTAGACAACAACAACCTCCTATTACTGCAGCAGATCTCATTGCCAGAGCTCCCTGGAGAATATGTCATAACAGTAACTGGGGAAAGATGTGTGTATCTTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000126838:ENST00000261336:29
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.227 A=NA C2=0.014
Domain overlap (PFAM):
C1:
PF076789=A2M_comp=FE(28.8=100)
A:
NA
C2:
PF076789=A2M_comp=PD(5.1=17.8)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CACCAGTGGGGCATCTTTACC
R:
TGGCAATGAGATCTGCTGCAG
Band lengths:
347-1619
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains