HsaINT1043219 @ hg38
Intron Retention
Gene
ENSG00000198870 | STKLD1
Description
serine/threonine kinase like domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28669]
Coordinates
chr9:133395600-133397294:+
Coord C1 exon
chr9:133395600-133395763
Coord A exon
chr9:133395764-133397163
Coord C2 exon
chr9:133397164-133397294
Length
1400 bp
Sequences
Splice sites
5' ss Seq
AAAGTGAGC
5' ss Score
5.89
3' ss Seq
CCTCTCTGCTCCTCTGCTAGGGA
3' ss Score
8.41
Exon sequences
Seq C1 exon
GGCACAGAAGCCATGCATCTGCGGAAGTCCCTCCGCCAGAGCCCAGGCAGCCTGAAGGCCGTCCTGAAGACAATGGAGGAGAAGCAGATCCCGGATGTGGAAACCTTCAGGAATCTTCTGCCCTTGATGCTCCAGATCGACCCCTCGGATCGAATAACGATAAA
Seq A exon
GTGAGCTCAGGGTCGGGGTTTATTTTAACCTGTGGATTTATCTTTCAACATCTCTCCACCCTAATACAAGCACAGCTAGTTGGCTTTGTAACGCCTCAAAGAACTCCATCACAGATGCCCTGATTATCCCTGCACAGCTGGGCTTTGCCCAGTTCTGGCTCTCCCAAACCGTGCTGCGGCGAGTAATCCCGAATGTACGGTGGAGTGAGCAGACTGACCCCCAGGAGGCACAGGAGGCGTAGCCCCCAGGACCCACGACACTTTTAGGGTTCCAGAAAAAAGTTTTCATTCTACATAAAAAAAAAAATTCCTAAAGACAATGGTCACCTTTAAATTTTTCATTCTAACTTACTTTAAAATCAGAAGACAAAAGTAAATACATAACACTGGCCGGGGCGGTGGCTCATGCCTATAATCCCAGCACTTTGGGGGGCTGAGGCGGGTAGATCACTTGAGCTCAGGAGTTCTAGTCTAGCCTGGGTAACATGGCGAAACCCCTGTCTCTACGAAAAATACAAAAAATTAGCTGGGTGTAGTGGTGCATGCCTGTGTTCCCAGCTACTGGGGAGGCTGAGGCAGGAGGATCGCTCGAGCCCGGGAGGCAGAGGTTGTTGCAGTGAGCTGAGATCTCGCCACTGCACTTCAGCCTGGGTGACAGAGTGAGACCCTGTCTCAAAAACAAAACAAAAACATATAACAAAGAATCCAGGCCGGACACGGTGGTTCACACCTGTAATCCCAGCAGTTTGGGAGGCTGAGGTGGGTGGATCACTTGAAGTCAGGTGTTCGAGACCAGCCTGGCCAACAGAGCGAAACCCCGTCTCTACTAAAAATAGAAAAAAAATTAGCTGGGCATGGTGGGGTGCGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGACAGAAGAAATGCTGGAACCCGGGAGGTGGAGGTTGCAGTGAGCCGAGATTGTGCCACTGCACTCCAGCCTAGGTGACAAGAGTGAAACTCCATCTAAAAAAAAACCCAAACAAAACAAAACAAAAAACCCAACATATAGCAAGGAATCCAGCCTGGGTCATATTCATCTTTATACCAACGCAGTTGTAAAATCTGGGTTTTCATGTTTCTATGGAGGCAGGGGACAAGAGCAAAAGTGCCAGGGCCCCGGACTGTCCCCCAGCTCTGTGAGCTGAGGCCCTGCCTCCATGGAGTACGTCCCTGGGTGTGGAATTGCTGGGGTGCTTGCCGGACACACTGGGGACACTATGAGAGACCCTGCCAAATGAATCCCAAAACAGGGAGTTCAGTGTCCAGTGTCCGCACCAATGGGCAGCCCGGAGCCAGAGGCAGAGGGAGAGCCCCACGGGGAGGTGGCAGGGGGCGCTGCTGGGTTACTCAGCCCTCTCTGCTCCTCTGCTAG
Seq C2 exon
GGACGTGGTGCACATCACCTTCTTGAGAGGCTCCTTCAAGTCCTCGTGCGTCTCTCTGACCCTGCACCGGCAGATGGTGCCTGCGTCCATCACCGACATGCTGTTAGAAGGCAACGTGGCCAGCATTTTAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000198870:ENST00000371957:9
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=FE(20.0=100)
A:
NA
C2:
PF0006920=Pkinase=PD(3.0=17.8)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCACAGAAGCCATGCATCT
R:
CTAAAATGCTGGCCACGTTGC
Band lengths:
294-1694
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains