HsaINT1044702 @ hg38
Intron Retention
Gene
ENSG00000137648 | TMPRSS4
Description
transmembrane protease, serine 4 [Source:HGNC Symbol;Acc:HGNC:11878]
Coordinates
chr11:118098985-118103253:+
Coord C1 exon
chr11:118098985-118099098
Coord A exon
chr11:118099099-118103100
Coord C2 exon
chr11:118103101-118103253
Length
4002 bp
Sequences
Splice sites
5' ss Seq
TCAGTAAGT
5' ss Score
9.14
3' ss Seq
TCCCTGCACTTGCCTTCCAGTCA
3' ss Score
8.45
Exon sequences
Seq C1 exon
ATGTCAAACCCCTGCGCAAACCCCGTATCCCCATGGAGACCTTCAGAAAGGTGGGGATCCCCATCATCATAGCACTACTGAGCCTGGCGAGTATCATCATTGTGGTTGTCCTCA
Seq A exon
GTAAGTGACAGCCCGTACCCGACTTTCACCCTCTAAGTAAATGACAGGGCCCAACCCCCACCCCCGCACTCACCCCTGAATAAGTGACAGTCCCCCACCCCTGCCCTCACCCCCTCAGTAAGAGGCAGTCCCACCCCTGCCCTCACCCACTCAGTAAGTGGCAGCCCCGCCCCTCCCATTATCACCTCAGTAAGTGGCAGCCCCTACTTGTCCTTCACCCCCTCAGTAAGTGGCAGCCCCCACCCCCACAGTCAGGGGCAGGTGATCTGCATAAAGCTTTGCAGAAAAAATCATTGGTATAATAAAAGGAATTTGAGGAGAAAAAAACAGAGAGAGAAAAAGAAAGAAGAGAGAAAGAGAGAAAGAAAGAAAGAAAGAAAGAAAAAGAAAGAAAGAAAGAAAGACATGTATCCACCCCCTGCTTTGAAGAGAGCCTTCTTCTAAAAGTGAAAGGGGAGATGAACTCAGCCCCCATCTGTTCCAGACGGCTTCTATCCCAGGTGACTTCTTCTAGAGGGAGAGCACAGTGGCATATGTTCCTAACCCACACATGCAATTTGCAGGGCTGCCACGCCCCCTGCCCCCTCCTTCCCATCTTCTGCAGATTGCAAGCTGAGTGGCTCTGAGCAGCGGCTGGAAGAACAGGGCGAGTTTCTGCTTGTGAGGAGGGGAGAAAGAGGAGGCAGCAGGGAAGACCCCCCAGGCAGTTGGCACCTGGCCCCCTTCAGCTTGGCCTTCACCATGGCCAGTACCTGAGGCCCAGTGTGGTCTTGAGCAGGCCTCTCTGCCTCAGGCCCTTATCTGTGATAAAGAAGATTCAACTGAAGGAGCAGGGATGTGGGTCCTTTTTGGCTCCCACATCCTATGATGGAGTCGTTGCCTTTGTTATCCACATGAGCACAGCAGGTTACTGACCACAACTTTTCACAGCAAGAAGTAGGGCACTGGGGACCAGACTAGGAATCAGGACACCCGAGACAGGGATTCTGGCTCTGCCTCTTGCTGCTGCGTGACCTTGAGTAAGTCCTTCACTGCCTCATACCCTCAGTCTCCGCACCTGTAAAATGTCCTTCCTCCCTCAGAGCGATATCATGAGCACCAGTGAGATAACACATGTAAAGGACCAAGCTAAAAACCAAGTTTTGCAAAAGAGTGTGTCATCACACAGCAGCAGACAAAATGTGACCCAGGACATGCATTTGCTAATTGGGGCAGGACTGCCTGTGCAGCCAGGGAATAGCTGGCCTTTCAGGAATTTGTACTTGTAACTGTGGTGACATTTCCAGCAGTAGCAGCCAACTGCCTGGTTAGAGGACACTGAGAGAGACTCTGGTCCTCATTCTACATGAGCACTGAGGCTCGGAGAGGAGGAGTGGCAGTCAGGGACAAAGCTGCGACAGAACCCCGGTCCCCTGATTGAACAGGTCCATTTCCATCTCGTGGCGGTGGAAATGCAGAGCCACAACATAAACCCCACTAAAAGCCCTGGGAGCCCTGGATGGTGTGAGATGCAGATGACCCCAAACCCTCTCTCCTTGACCTTGGTTGCCCACATGATGGAGGTTTGCAGTGACATCAGCAGACTTGCCATCCTGTTCTATTCAGGCTAATGTTAAAGTGAGCTTGCTTTCCATAAGCATACACCCTGCCACAGTGGAGATAAAGGGGACCAAAGTTATCCAGCGAAAGCCAAGCAGGCACTAAAGCATAATTCAGAGCTGGACACTCCCTGTCCCAGAAGGTCCTATGTGGCTTCCATATCCTGGGCCCCCAGATTCTGCAATCAGAGGTTGTTACCCAGTCCTCCATCCTGGGCCGGGTTCCCTCAACCTTATGGCTTCTGGAGTCTCAACTGGCAATGCTGTCTCCTGGATTTGTCCCAGGAGGCTGGAGTGACTCTGCCTTACCCTGGCTCCTGATTATAAACCAAACTCCAAAGAGCTAAGTAATATCTAGCTCCTCCTTCTCCCTTGCTTCACTCAAGCCAGGAGTGTCAGGGCCAGCAGATCACATCTCAAGCTTCCCCAGAGAATTAGATGGGCCCTGGCTCTACACTGGAAGCACTGTGTGCCCTGGGAAAATAAAGCCTGACCTTCAATTCTCCACGTCCCTGTTTGTAATGTGAGTTAGTAATAACACTTCCCTCCCAAGACTGTTGTCAGGATTACGTGAGGAAATGTATGGAAAGCTCCTGACACGGTGACAAGCAGGGACCATTATTAGATTTAACGCCACTACTCTTAAGACCAGCCCAGGGTGATACTGGACTGGAGAGGGTCCCATCAGGCCAAGACAGAATTCAGTTAGGAAGGAGGAGTTCCCTCCTGCCAGGGTGTTTGGCTGTGGGTCTTCACTAAGGAAAAGTTTGTTTGTATGTCTGTCTGCTTGTTTGTTTGAGACAAGGTCTTGCTCTCTTTCCCAGGCTAGAGTGTAATCGTGTGATCACCTCACTGCAGCCTCAAACTTCTAGGCTCAAGCAATCCTCCTGCCTCAGCCTCCCAAGTAGCTAGGACCACAGGGGCACACCACCATGCCTGGCTAATTCTTTTTTTAATTTTTCGTATAGACGAGGGTCTCACTATGTTGCCGAGACTGATCTTGAATTCCTGGGCTCAAACAATCCTCCTGCCTTGGCATCCCAAAGTGCTGGGATTACAGGTGTGAACTACCATGCATGGCCAGAAAAAGTGTTAAAATATCAGTTCCCTGAAGGATTAAACACACTCAACATCTTTCCATCATCCCAAAATGGCAAAAGAGCAACAGAATTTGAAAGCAGCTGGCAGAATCTAAAGACGGCGAGCAGAAACAAAACAAAACCGAGGACCAACCCCTTCACAGATCTTTCTCTTTTTTTCTTAATTTTAGTTCTTTTTACTTATATATTTTAATTATTTTTTTCTTCAAATTTTATTCCAAGTTCTGGGGTACACGTGCAGGATGTGCAGGTTTGTTACGTAGGTAAGCGTGTGCCATGGCGGTTTGCTGCACTGATCAACCCTTCACTGAGGTATAAAGCCCAGCAACCATTAGCTATATTTCCTGATGCTCTCCCTCCTCCCGCCTCCCCCCGACAGGCCCCAGTGTGTGTTGATCCCCCTGCACGTGTCCATGTGTTCTTACCATTTAACAGTTCTTTCACCCAGGTAAAAGCACCCAATTCTAGAACTATACTTGATAGTTACGAGACATTTTCATGACTACCATCATACCACATGCTCTCAACAGCCCTGCGAGGCAGATATTATAGATATCATCATCCCATTGTACAGATGAGGAAACTGAGAACTAAGAAGGGAAAGCGATCCATATAAAGTTGCACAGTAAGGCCGAGTGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGTGGATCACCTGAGGTCAGGAGGTCGAGAGCAGCCCAGCCAACATGGTGAAACCCCGTCACTACTAAAAATACAAAAAATTAGCCAAGTGTGGTGGCATGTGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGACTCACTTAAACTTGGGAGGCAGAGGCTACAGTGAGCCAAGATCCCGCCACTGCACTCCAGCCTGGATGACAGAGTGAGACTCGGTCTCAAAAAAAAGAAAAAAGTTAAGTTCCACAGTGGGTGGCAGGGCTAGGACTCAGAACTGGGTCTTCAGACTCCGGGTTCCTCCTCTTTTACCAGTACATACTGAGCGAGCACTGGAGGGTAAGAGGCAGTTACCAGCCTGTTTCTCCCACACACGTGACCTCTCTTGACTCCGCAGACATCTTGTGGGGGTGGGGCCGGTGTTACTATCTCCACTTTACAGACAAGGAAGCTGAGGCTCAGGCCCAAGTCTGTGTGCTACCAAGTAGCAAAACTGAGCCTGGAACTCACACATGCGTGTCTGAGAGCCCAGCACTATCGCCAGGAAAACCCAGCGTCTCCCTGCTCAAGCCTGACCCTCAGCCCTCTCTGCCTCTCCCTGCACTTGCCTTCCAG
Seq C2 exon
TCAAGGTGATTCTGGATAAATACTACTTCCTCTGCGGGCAGCCTCTCCACTTCATCCCGAGGAAGCAGCTGTGTGACGGAGAGCTGGACTGTCCCTTGGGGGAGGACGAGGAGCACTGTGTCAAGAGCTTCCCCGAAGGGCCTGCAGTGGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000137648:ENST00000534111:3
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.126 A=NA C2=0.011
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0005713=Ldl_recept_a=WD(100=61.5)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains