HsaINT1044716 @ hg38
Intron Retention
Gene
ENSG00000176040 | TMPRSS7
Description
transmembrane protease, serine 7 [Source:HGNC Symbol;Acc:HGNC:30846]
Coordinates
chr3:112076876-112078878:+
Coord C1 exon
chr3:112076876-112077144
Coord A exon
chr3:112077145-112078741
Coord C2 exon
chr3:112078742-112078878
Length
1597 bp
Sequences
Splice sites
5' ss Seq
CAGGTGTGT
5' ss Score
6.99
3' ss Seq
ACTTCCAATGTGTTTTGCAGATA
3' ss Score
9.72
Exon sequences
Seq C1 exon
GCTGTCAGATCCCACACCATGGACTGCACACCTCGGGATGTATGTTCAGGGGAATGCCAAGTTTGTCTCCCCGGTGAGAAGAATTGTGGTCCACGAGTACTATAACAGTCAGACTTTTGATTATGATATTGCTTTGCTACAGCTCAGTATTGCCTGGCCTGAGACCCTGAAACAGCTCATTCAGCCAATATGCATTCCTCCCACTGGTCAGAGAGTTCGCAGTGGGGAGAAGTGCTGGGTAACTGGCTGGGGGCGAAGACACGAAGCAG
Seq A exon
GTGTGTGTATGAATGAATGGTCATGCCCTTCCCCTGCAGAGGATGATAAGGTGTTTATGTAGTGCTTTAGGGTTCACAGAGAGGGTTTGTGTATATGATCTCCTTTGAACCTCCTGACAACTCTGGAAGGTTGGATTGGAGGAGGGTACTGTTATTTCTTTTTAATGATGCTATCCACCTGCTTTAAAAGAAGCAGGGCTCACCTTATAAAGAGGGAGAGGACTGTGTATGAGCAAGGCAGGATTGACTAGATAGTCATGGGCCCTTTTCAAACTCTGAAGGTTATGCTATGTTATTCACTAGAGAAGGAGCAATTCCTCCCTTTTCATTCAAAGAAATGATTCATTTATAAAGGAGAGAAGGACACACATGCACATCCCACTATGTCAACTCATAGGCAACAGTCTGGGAGACTATGTGGGTATGACCTGTGCCTGTGCAATTGGCCAAGGGATGAGAGTAAGGGCTGAACTTCAGACTGCCCTTAGTTTCCAGACCAGAAACTCAGGCCTGGAGGTTATACCTCCAGGATTTGGATTTGGTCCACCCAGAGGAGATACCTTTTTGCTATTTCTCTGACGGGAGAGGACATCTTTTCAATATGCATAAAGATCAGGCTGTATAGTAGGGAAGTCCCTACATCTACCCTGCCAAGGTTTTTCATGGTCCAGGATTCAAGGTGGGATTCTGAATATATAGTGAGGGGAAGAATCCAATGCTTTGTGAATGTATCCCCAAACGCTAGTGCTAATATTTTCCCTTGATCTTTCAATCACCTCACCTTCTTTTGCCATCCTTTTCAAGGGTTTAGGACACGTACAGCATCTGTAATTCCTGAACCTTGCCCTGTAGCCTCGTTTTGACACTCTAAAGTGTGGGCAACTTCTCAAAGGCAGCTTCTCAGTGCTTTCATTTAGTGATTGAAGTAGTAATACCACCAGCTTGGGTCCACTGAAGTCTCAGGGTCCCAAGGAGGGAAGGCAGCTGACTGTGAACACTTGTAACTTTGATAGGTTACTGTGCTCAGTGCTTTGATTACATTATCATATATCACAGGAGAAAAGCATCTGCCCAACCAACTTATCATGAGATGTTTTCTTTATAAGCCTGGGTATGTGTGTGTACACTTATTTTTCTGAATCATCTTAGCCAGGTAGGTTCAAAAGGAAGTGAAACAGCTATTTGCAAACTGTTAGGTTTTTATGGTTCATCAGAGACTCCCATATATCAGTTATGCTGCTCCATTTAAAGAGCTCTCTTGAATAGTAGATATTAGTAATAACTGTTGCTGACTTACCATCCTACGGAAAACAGGAGGGAAATGGTGAGGAATATGGCACAGTTGTTCAAGTAATTGAGTCAGACCTTGGGTCTGAATCTTGTGTTACTTGCTAGTGGTGTGTCACTGGGCAAGCCCTTTAATCTCCTAGCACTCGATTTCTTCATCAGCAAAATGAGGATAATAGTAGAATTTACCTCAAGGGAATTGCCGCTATGAGGGTAAAAGGAGATAATGTGTGTTAACTTTTCAAATGAAGTCCTGAATACATGCGGCCATTACCACTAACATCATTTCTACTTCCAATGTGTTTTGCAG
Seq C2 exon
ATAATAAAGGCTCCCTCGTTCTGCAGCAAGCGGAGGTAGAGCTCATTGATCAAACGCTCTGTGTTTCCACCTACGGGATCATCACTTCTCGGATGCTCTGTGCAGGCATAATGTCAGGCAAGAGAGATGCCTGCAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000176040:ENST00000419127:14
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=FE(39.1=100)
A:
NA
C2:
PF0008921=Trypsin=FE(19.6=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGCACACCTCGGGATGTATG
R:
GCACAGAGCATCCGAGAAGTG
Band lengths:
349-1946
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains