HsaINT1045698 @ hg38
Intron Retention
Gene
ENSG00000137267 | TUBB2A
Description
tubulin beta 2A class IIa [Source:HGNC Symbol;Acc:HGNC:12412]
Coordinates
chr6:3155625-3156152:-
Coord C1 exon
chr6:3156044-3156152
Coord A exon
chr6:3155736-3156043
Coord C2 exon
chr6:3155625-3155735
Length
308 bp
Sequences
Splice sites
5' ss Seq
CTGGTGAGT
5' ss Score
10.1
3' ss Seq
TCAGTTCTTATTTCCTGCAGGTA
3' ss Score
9.83
Exon sequences
Seq C1 exon
TTTTGGGAGGTCATCAGCGATGAGCATGGGATCGACCCCACAGGCAGTTACCATGGAGACAGTGACTTGCAGCTGGAGAGAATCAACGTGTACTACAATGAGGCTGCTG
Seq A exon
GTGAGTAGCGGGATGTGTGTGCCCAGGAATCCTTGCTTTCCATGATGTGGGAGATGAAACGTCCCAGGAACATGCACGTGACAAAGGCATGCTTCTTGCATATTCATTTCAAATGCCAACTGCTGGAAAAACATGTTTTATGGTTTCCTAAGATTCCTGCCTGTTTGCCACGGCTAAGCACACTCAGGACCTCCTTTTTCTTAAAAGCAGAAAATCTCCTGTTCTCCTTTTGTCTCAGATGCTGGAATTGAATGCTGCTGTGAGTCCCTCCCCAAGCACAGGCCTGAGTCAGTTCTTATTTCCTGCAG
Seq C2 exon
GTAACAAATATGTACCTCGGGCCATCCTGGTGGATCTGGAGCCTGGCACCATGGACTCTGTCAGGTCTGGACCCTTCGGCCAGATCTTCAGACCAGACAACTTCGTGTTCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000137267:ENST00000333628:2
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.108 A=NA C2=0.026
Domain overlap (PFAM):
C1:
PF0009120=Tubulin=FE(16.2=100)
A:
NA
C2:
PF0009120=Tubulin=FE(16.7=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTGGGAGGTCATCAGCGATGA
R:
CGAACACGAAGTTGTCTGGTCT
Band lengths:
218-526
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains