MmuEX0003288 @ mm10
Exon Skipping
Gene
ENSMUSG00000026842 | Abl1
Description
c-abl oncogene 1, non-receptor tyrosine kinase [Source:MGI Symbol;Acc:MGI:87859]
Coordinates
chr2:31688551-31778507:+
Coord C1 exon
chr2:31688551-31689942
Coord A exon
chr2:31695749-31695892
Coord C2 exon
chr2:31778334-31778507
Length
144 bp
Sequences
Splice sites
3' ss Seq
TGTTTTTTAAATATTCTCAGGGG
3' ss Score
6.97
5' ss Seq
CAGGTACCT
5' ss Score
8.16
Exon sequences
Seq C1 exon
GACTTTCAGTGCCGTTGGCCCTTTTCTGACTTTTCTGTGAATAGTTTTATCTAAAGTTCCCCTCTTGCAAAGAAAGTGTTCCTCAGCTCGCAACGTAGACTTAGATTGAAGAAACTTTTGGCATTGCGGTTACATGACTTCAAACTAATTACCCTGGAAAAGAATTCCAGGCTCCTGTTTACATGTGTGAACCTCAAACCCAGCTTCCCTTTGTCATGGAAGTTGTCTGTCTGTGATTGACCCAAGTTACTGACCCAAGACGGTGGTGTGAAGTTCTGGGTATATACTGTTGCCTGCTAACCCCCACGGACCATTCTGAAAAGTCTTGAACCCTCTTCTGGAAAGGGGCACCTATTATTGCTTTATGGGGCAGCAGCCTGGAAAAGTTCTTGGGGACCAAAGAAGGCCTAGTTTGCCCGCCCTGCATTTTATCAAAGGGGCAGGGAAGAGGGACTCATCGAGGCATGGGGGCCCACACTGCAATGTCTTTGTGGAACACG
Seq A exon
GGGCTGGAGATGTGGCTCAGAGGCTAAGAGAGCTTATTGCTCTTCCAGAGGATGAGAGTTCAGTTCCCAGCACCCACACTGTGGCTCACAGCCATCTGTAACTCCAGATCTTCAGGAGATCCAACAGTCTTCTGGCCTCTGCAG
Seq C2 exon
AAGCCCTGCAGAGGCCAGTGGCATCTGACTTTGAGCCCCAGGGTCTCAGCGAAGCAGCTCGATGGAACTCCAAGGAAAACCTTCTTGCTGGGCCCAGTGAAAATGACCCCAACCTTTTTGTGGCACTCTATGATTTTGTGGCCAGTGGAGATAACACTCTCAGCATCACTAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026842_MULTIEX1-2/4=C1-3
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.826 A=0.818 C2=0.105
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF0001823=SH3_1=PU(38.3=30.5)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCAGCAGCCTGGAAAAGTTCT
R:
TTGGGGTCATTTTCACTGGGC
Band lengths:
243-387
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types