Special

MmuEX0003823 @ mm10

Exon Skipping

Gene
ENSMUSG00000014852 | Adamts13
Description
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13 [Source:MGI Symbol;Acc:MGI:2685556]
Coordinates
chr2:26988339-26990445:+
Coord C1 exon
chr2:26988339-26988419
Coord A exon
chr2:26989238-26989419
Coord C2 exon
chr2:26990310-26990445
Length
182 bp
Sequences
Splice sites
3' ss Seq
TGATGGCCCTGTTCTCAAAGCGG
3' ss Score
3.83
5' ss Seq
CAGGTCATC
5' ss Score
2.07
Exon sequences
Seq C1 exon
AATATGTCACGTTCCTGATTGTTACTCCCAACATGACCAACGCACACATTGTCAACCGCAGGCCTCTCTTCACACACTTGG
Seq A exon
CGGTGAGGATCCAGGGCCACTACATTGTGGCAGGGAAGACTAGCATCTCACCCAACACCACCTACCCTTCCCTTCTGGAGGACTACCGTGTGGAATACAGAGTGACTCTCACTGAGGACCAGCTGCCCCACTTAGAGGAGATTCACATCCGGGGACCCGTCCGGGATGACATTGAGATTCAG
Seq C2 exon
GTGTACAGACGATATGGAGGAGAATATGGGGATCTTACACACCCAGACATCACCTTTTCCTACTTTCAACTGAAGCAGCAGGCAGCCTGGGTATGGACCGCTAAGCGTGGACCCTGCTCAGTGAGCTGTGGGGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000014852-'15-21,'15-20,18-21
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact

ORF disruption upon sequence exclusion

No structure available
Features
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):

C1:
PF059869=ADAM_spacer1=FE(21.8=100)
A:
PF059869=ADAM_spacer1=FE(48.4=100)
C2:
PF059869=ADAM_spacer1=PD(17.7=47.8)


Main Inclusion Isoform:


Main Skipping Isoform:
NA


Other Inclusion Isoforms:


Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
HIGH PSI
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGTCACGTTCCTGATTGTTACTCC
R:
CTCACTGAGCAGGGTCCACG
Band lengths:
202-384
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types