Special

MmuEX0004904 @ mm9

Exon Skipping

Gene
ENSMUSG00000032826 | Ank2
Description
ankyrin 2, brain [Source:MGI Symbol;Acc:MGI:88025]
Coordinates
chr3:126726210-126735231:-
Coord C1 exon
chr3:126735034-126735231
Coord A exon
chr3:126732137-126732235
Coord C2 exon
chr3:126726210-126726308
Length
99 bp
Sequences
Splice sites
3' ss Seq
ACTGTCGCTTTGTTTCGCAGTCT
3' ss Score
9.18
5' ss Seq
ATTGTGAGT
5' ss Score
7.35
Exon sequences
Seq C1 exon
AATGGGCTGTCCCCGCTTCACATGGCTGCGCAGGGGGACCACGTGGAATGTGTGAAGCACCTGCTCCAATACAAGGCGCCTGTCGATGACGTCACCCTGGATTACCTGACGGCTCTTCATGTTGCTGCACACTGTGGGCACTACCGTGTAACCAAACTCCTGCTGGACAAGAGAGCCAACCCGAACGCAAGAGCCCTG
Seq A exon
TCTGGCCTCACACCAATACATGTGGCTGCCTTCATGGGCCACTTGAACATTGTCCTCCTTCTGCTGCAGAACGGAGCCTCTCCAGATGTCACTAACATT
Seq C2 exon
CGTGGTGAGACAGCTCTTCACATGGCGGCCCGGGCTGGGCAGGTGGAAGTGGTCCGATGTCTTCTGAGGAATGGTGCTCTTGTGGATGCCAGAGCCAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000032826_MULTIEX2-2/2=C1-C2
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (No Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF127962=Ank_2=PD(33.7=47.0),PF136371=Ank_4=PU(57.4=47.0)

							
A:
PF127962=Ank_2=PD(33.3=93.9)

							
C2:
PF127962=Ank_2=PU(23.3=60.6)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000126883f3048A





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000036378, ENSMUSP00000087808, ENSMUSP00000126883, ENSMUSP00000126883f3045A, ENSMUSP00000126883f3047A, ENSMUSP00000127248, ENSMUSP00000130908, ENSMUSP00000130908f3049A
          









    
Other Skipping Isoforms:
NA
  



Associated events







Other assemblies


mm10




Conservation


Human
(hg38)
chr4:113258313-113258411 
ALTERNATIVE
HsaEX0004123
(ANK2)
Human
(hg19)
chr4:114179469-114179567 
ALTERNATIVE
HsaEX0004123
(ANK2)
Rat
(rn6)
chr2:231333091-231333188 
Cow
(bosTau6)
chr6:13501242-13501340 
Chicken
(galGal4)
chr4:56427494-56427592 
ALTERNATIVE
GgaEX0018068
(chAnk2)
Chicken
(galGal3)
chr4:58382670-58382768 
ALTERNATIVE
GgaEX0018068
(Q90716_CHICK)
Zebrafish
(danRer10)
chr7:57666240-57666338 
HIGH PSI
DreEX6007819
(ank2b)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
CTGACGGCTCTTCATGTTGCT

				
R: 
GGCATCCACAAGAGCACCATT

				
Band lengths: 
183-282

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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