Special

MmuEX0006576 @ mm9

Exon Skipping

Gene
ENSMUSG00000027104 | Atf2
Description
activating transcription factor 2 [Source:MGI Symbol;Acc:MGI:109349]
Coordinates
chr2:73661258-73666735:-
Coord C1 exon
chr2:73666529-73666735
Coord A exon
chr2:73663316-73663460
Coord C2 exon
chr2:73661258-73661363
Length
145 bp
Sequences
Splice sites
3' ss Seq
AACCTTTCTCATCTGGGCAGACG
3' ss Score
7.04
5' ss Seq
AAGGTAAGT
5' ss Score
11
Exon sequences
Seq C1 exon
GCTTCTCCAGCTCACACAACTCCTCAGACCCAAAATACAAGTGGCCGTCGAAGAAGAGCAGCTAATGAAGATCCTGATGAGAAAAGGAGGAAGTTTCTAGAACGAAATAGAGCAGCAGCTTCAAGATGCCGACAAAAAAGGAAAGTGTGGGTTCAGTCCTTAGAGAAGAAAGCAGAAGACTTGAGTTCACTAAATGGCCAGCTGCAG
Seq A exon
ACGAAGCTTCTTCCAAGAGCCAAAGACCACCTAACAAAACCTCCAATGCCAGACATGAGATACTCTCTTTTTAGTTGTTGTCCAAGAGACTCACAAAACATACAATCTATTGCTGTTGCCCTTGATAAGCCCCCAGAGGTAGAAG
Seq C2 exon
AGCGAAGTCACCCTGCTGAGAAATGAAGTGGCCCAGCTGAAACAGCTTCTTCTGGCTCATAAAGATTGCCCTGTAACTGCCATGCAGAAGAAGTCTGGCTATCATA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000027104-'29-26,'29-25,32-26
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.937 A=0.837 C2=0.663
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0017016=bZIP_1=PU(70.8=66.7)

							
A:
PF0771610=bZIP_2=PD(9.6=10.2)

							
C2:
PF0017016=bZIP_1=PD(26.2=47.2)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000058521f2052A





     
                   









    
Main Skipping Isoform:
ENSMUSP00000058521





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000088311, ENSMUSP00000097588, ENSMUSP00000107636, ENSMUSP00000107638, ENSMUSP00000107641, ENSMUSP00000107647, ENSMUSP00000107648, ENSMUSP00000126034, ENSMUSP00000130822
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
TCCAGCTCACACAACTCCTCA

				
R: 
TCAGCTGGGCCACTTCATTTC

				
Band lengths: 
242-387

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"