Special

MmuEX0007310 @ mm9

Exon Skipping

Gene
ENSMUSG00000027580 | BC006779
Description
cDNA sequence BC006779 [Source:MGI Symbol;Acc:MGI:2385169]
Coordinates
chr2:180964261-180965155:-
Coord C1 exon
chr2:180965039-180965155
Coord A exon
chr2:180964772-180964967
Coord C2 exon
chr2:180964261-180964614
Length
196 bp
Sequences
Splice sites
3' ss Seq
ACATGAGTGACCTCATATAGGTA
3' ss Score
3.27
5' ss Seq
AAGGTGAGG
5' ss Score
9.16
Exon sequences
Seq C1 exon
GAGCATTACCCTTCACCACCGGATCCGCCAGGCCCCCAACCCATATGCAGCAGAGATCAGAAAATTTGATGCCCAGCTTCGGGAAGGGAAAATATTCTCAAAGGAGGATCTTAGAGT
Seq A exon
GTACAGGAGAGTCTTGGGGAAGGCACGCAAACATGAACTGGAGCGGCACTCGGTCATCCTGTGCACGTGCTCCTGTGCGGCATCAAAGAGCCTGAAAATTCTGAATGTTCGACAGATCCTTATCGACGAGGCAGGCATGGCCACTGAGCCAGAGACCCTTATCCCCTTGGTGTGCTTCTCAAAGACGGTTGAGAAG
Seq C2 exon
GTGGTTCTGCTTGGAGACCACAAGCAGCTTCGGCCTGTGGTCAAGAGTGAACAGCTGCAGAGTCTGGGGATGGATCGGTCTCTCTTTGAGAGGTACCACAGGGATGCCATCATGCTGGACACACAGTACCGTATGCATAAGGACATCTGTTCCTTCCCCTCCGTGGAGTTCTATGGGGGAAAGCTAAAGACCTGGTCTGACCTGAGGCGTCTGCCTAGTATCCTGGGTCACACTGGCAAGCCGAGCTGTTCCGTCATCTTCGGCTCTGTGCAGGGCCATGAGCAGAAGCTGCTGGTGTCCACCGAGGATGGCAATGAGAACTCTAGGGCCAACCCAGAGGAAGTCACACAGGTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000027580_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.127 A=0.000 C2=0.145
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF130861=AAA_11=FE(15.6=100)

							
A:
PF130861=AAA_11=FE(26.0=100)

							
C2:
PF130861=AAA_11=PD(6.4=13.6),PF130871=AAA_12=PU(45.4=79.7)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000091756





     
                   









    
Main Skipping Isoform:
ENSMUSP00000029102





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000084714, ENSMUSP00000104459, ENSMUSP00000112917
          









    
Other Skipping Isoforms:
NA
  



Associated events







Other assemblies


mm10




Conservation


Human
(hg38)
chr20:63561082-63561194 
HIGH PSI
HsaEX6079218
(HELZ2)
Human
(hg19)
chr20:62192435-62192627 
HIGH PSI
HsaEX6079218
(RP4-697K14.7)
Rat
(rn6)
chr3:176732432-176732509 
ALTERNATIVE
RnoEX0041519
(Helz2)
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
chr20:14274209-14274401 
HIGH PSI
GgaEX6023233
(HELZ2)
Chicken
(galGal3)
chr20:9726251-9726443 
HIGH PSI
GgaEX6023233
([1])
Zebrafish
(danRer10)
chr6:58612807-58612999 
HIGH PSI
DreEX6024662
(helz2)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
GAGCATTACCCTTCACCACCG

				
R: 
TACGGTACTGTGTGTCCAGCA

				
Band lengths: 
250-446

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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