MmuEX0012664 @ mm10
Exon Skipping
Gene
ENSMUSG00000063681 | Crb1
Description
crumbs family member 1, photoreceptor morphogenesis associated [Source:MGI Symbol;Acc:MGI:2136343]
Coordinates
chr1:139248119-139272673:-
Coord C1 exon
chr1:139272594-139272673
Coord A exon
chr1:139271407-139271575
Coord C2 exon
chr1:139248119-139249075
Length
169 bp
Sequences
Splice sites
3' ss Seq
ATCTACTTATATTTGTTCAGGAT
3' ss Score
6.89
5' ss Seq
AAGGTAAAC
5' ss Score
8.14
Exon sequences
Seq C1 exon
ACATGGATTAACTATGTCATCAAAGGTGACCTGAGACTTTCAACCTCCCTACTTCACCTTACCAGTTGCTGGAATTTCAG
Seq A exon
GATCTTTGATAAAGGACATCAGTGAGGCAAAGTCTCTCAAAGGAACAAGCCAGATGTTTCTGTAACAGACTGAGTTCAAATCCTCATCAGCTTCTTTCTCCTTGGGAAATTGGAAATTAATTTTAAGCCTTATGAATCATGTTTTCTTTTTGATGGCATCATCATTAAG
Seq C2 exon
GAATTCACTGTGAAGAAGACGTTGATGAATGTTTACTGCACCCTTGCCTAAATGGTGGTACTTGTGAGAACCTGCCTGGGAATTATGCCTGTCACTGTCCCTTTGATGACACTTCTAGGACATTTTATGGAGGAGAAAACTGCTCAGAAATTCTCCTGGGCTGCACTCATCACCAGTGTCTGAACAATGGAAAATGTATCCCTCATTTCCAAAATGGCCAGCATGGATTCACTTGCCAGTGTCTTTCTGGCTATGCGGGGCCCCTGTGTGAAACTGTCACCACACTTTCATTTGGGAGCAATGGCTTCCTATGGGTCACAAGTGGCTCCCATACAGGCATAGGGCCAGAATGTAACATATCCTTGAGGTTTCACACTGTTCAACCAAACGCACTTCTCCTCATCCGAGGCAACAAGGACGTGTCTATGAAGCTGGAGTTGCTGAATGGTTGTGTTCACTTATCAATTGAAGTCTGGAATCAGTTAAAGGTGCTCCTGTCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000063681_MULTIEX1-4/4=3-C2
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
PF0000822=EGF=PD(20.6=31.8)
C2:
PF126612=hEGF=PD(23.1=0.9),PF0000822=EGF=WD(100=7.8),PF0000822=EGF=WD(100=10.9),PF0221019=Laminin_G_2=WD(100=43.1),PF0000822=EGF=WD(100=9.7)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACTTCACCTTACCAGTTGCTG
R:
TCCATGCTGGCCATTTTGGAA
Band lengths:
257-426
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types