MmuEX0012669 @ mm10
Exon Skipping
Gene
ENSMUSG00000035403 | Crb2
Description
crumbs family member 2 [Source:MGI Symbol;Acc:MGI:2679260]
Coordinates
chr2:37792054-37793867:+
Coord C1 exon
chr2:37792054-37792219
Coord A exon
chr2:37792623-37792980
Coord C2 exon
chr2:37793099-37793867
Length
358 bp
Sequences
Splice sites
3' ss Seq
TCCTGCCTCTACTTCCCCAGTTT
3' ss Score
7.46
5' ss Seq
CAGGTGGGT
5' ss Score
8.56
Exon sequences
Seq C1 exon
CCCAATCCCTGTTTCAATGGTGGCACGTGCCACGTCACCTGGAATGACTTCTACTGCACCTGCTCCGAGAACTTCACGGGGCCCACCTGTGCCCAGCAGCGATGGTGCCCCAGGCAGCCATGCCTGCCTCCTGCCACCTGTGAGGAGGTTCCAGATGGCTTTGTGT
Seq A exon
TTTAGGGACTATGGATATGGGCCCCTACACCCCATTTGTTGGGTGCTAGGGATGGAACCCAAAGCCTCCTACAAGCTAGGCAGTCTACCAACCGAAGCTACTCTGCCAGCCTTACAGAAGGTGAGGAGGAGAAGGATATGACTGGACCAGCACCTGTGTGCAGTGAAGAGCGAGCCTCCTTCAGGGAGGAGGGGAGCAGGTTAGATTTAGGAGGAGCTAAGATTATTAATATGTCTAGGGCCTTCAAGGTAGCAGGTATTGTGGTCCCCCTAGGACTACCCCGGAACTGATTCCCTCCCAGGAGGAGAATGCATAAGGGGTGGAAGAGGGAGCTGCAGTTTCTGAGATCAGGTGACAG
Seq C2 exon
GTGTGGCCGAGGCCACGTTCCGCGAGGGCCCTCCTGCTGTGTTCACAGGCCACAACGTGTCCTCATCGCTCAGCGGGCTCACCCTGGCCTTCCGCACGCGCGACTCCGAGGCTGGGCTACTGCGCGCCGTCTCCGCCGCAGGTGCCCACTCCAATATCTGGTTGGCGGTGCGCAACGGCTCGCTGGCAGGAGATGTGGCGGGTTCGGTGCTGCCCGCGCCCGGGCCGCGCGTGGCCGACGGCGCCTGGCATCGCGTGCGCCTAGCCCGGGAGTTCCCACAGGCCGCTGCCTCGCGCTGGCTGCTGTGGCTGGACGGCGCGGCGACACCCGTGGCCTTGCACGGCTTGGGCGGCGACCTGGGCTTTCTGCAGGGTCCGGGTGCAGTGCCTCTGCTACTGGCTGAGAACTTCACGGGCTGCCTGGGCCGCGTGGCACTTGGCGACTTCCCGTTACCCTTGGCGCCACCGCGGTCTGGCACGGTGTCTGGGGCGCGCGAGCAC
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000035403_CASSETTE2
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.008
Domain overlap (PFAM):
C1:
PF0000822=EGF=PD(90.3=50.0)
A:
NO
C2:
PF0221019=Laminin_G_2=WD(100=46.3),PF0000822=EGF=WD(100=12.1),PF126612=hEGF=WD(100=5.1)
Main Inclusion Isoform:
ENSMUST00000050372fB1120
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCCCTGTTTCAATGGTGGCAC
R:
CACATCTCCTGCCAGCGAG
Band lengths:
358-716
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types