Special

MmuEX0013341 @ mm9

Exon Skipping

Gene
ENSMUSG00000061740 | Cyp2d22
Description
cytochrome P450, family 2, subfamily d, polypeptide 22 [Source:MGI Symbol;Acc:MGI:1929474]
Coordinates
chr15:82202820-82204486:-
Coord C1 exon
chr15:82204334-82204486
Coord A exon
chr15:82204103-82204263
Coord C2 exon
chr15:82202820-82203007
Length
161 bp
Sequences
Splice sites
3' ss Seq
ACTGACATTTCTACTCCCAGGAC
3' ss Score
7.84
5' ss Seq
ATGGTGTGG
5' ss Score
2.28
Exon sequences
Seq C1 exon
GTATAGTCCTAGCACGGTATGGGCCTGCCTGGCGTCAGCAGCGGCGCTTCTCTGTGTCTACCATGCACCACTTTGGCCTGGGCAAGAAGTCACTGGAGCAGTGGGTGACTGAGGAGGCCAGATGCCTCTGTGCCGCCTTCGCTGACCATACTG
Seq A exon
GACACCCTTTCAGCCCTAACACCCTATTGGACAAAGCAGTGTGTAACGTGATCGCGTCCCTCCTCTATGCCTGCCGCTTTGAGTACGATGACCCACGCTTCATCAGGCTACTGGGCTTGTTGAAGGAAACTCTTAAGGAGGAAGCTGGATTCCTACCCATG
Seq C2 exon
GCCGAGTACAACAGGAAATCGATGAAGTCATAGGGCAGGTGCAGTGTCCAGAGATGGCAGACCAGGCTCGCATGCCCTACACCAATGCTGTCATTCATGAGGTGCAGCGCTTTGCAGACATTCTCCCTCTTGGTGTACCTCACAAGACTTCTCGTGACATTGAACTACAGGGCTTCCTTATCCCTAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000061740_MULTIEX1-1/3=C1-C2
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0006717=p450=FE(11.1=100)

							
A:
PF0006717=p450=FE(11.5=100)

							
C2:
PF0006717=p450=FE(13.4=100)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000023083





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000131100
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr22:42128784-42128944 
HIGH PSI
HsaEX7010893
(CYP2D6)
Human
(hg19)
chr22:42524786-42524946 
Rat
(rn6)
chr7:123601478-123601638 
HIGH PSI
RnoEX0025888
(Cyp2d4)
Cow
(bosTau6)
chr5:113611370-113611530 
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
chr20:25688981-25689141 
ALTERNATIVE
DreEX0025451
(cyp2p10)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
TAGTCCTAGCACGGTATGGGC

				
R: 
GACAGCATTGGTGTAGGGCAT

				
Band lengths: 
242-403

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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