HsaEX7010893 @ hg38
Exon Skipping
Gene
ENSG00000100197 | CYP2D6
Description
cytochrome P450 family 2 subfamily D member 6 [Source:HGNC Symbol;Acc:HGNC:2625]
Coordinates
chr22:42128174-42129185:-
Coord C1 exon
chr22:42129033-42129185
Coord A exon
chr22:42128784-42128944
Coord C2 exon
chr22:42128174-42128350
Length
161 bp
Sequences
Splice sites
3' ss Seq
CCCGCATCTCCCACCCCCAGGAC
3' ss Score
10.24
5' ss Seq
GAGGTGCGG
5' ss Score
6.79
Exon sequences
Seq C1 exon
GGGTGTTCCTGGCGCGCTATGGGCCCGCGTGGCGCGAGCAGAGGCGCTTCTCCGTGTCCACCTTGCGCAACTTGGGCCTGGGCAAGAAGTCGCTGGAGCAGTGGGTGACCGAGGAGGCCGCCTGCCTTTGTGCCGCCTTCGCCAACCACTCCG
Seq A exon
GACGCCCCTTTCGCCCCAACGGTCTCTTGGACAAAGCCGTGAGCAACGTGATCGCCTCCCTCACCTGCGGGCGCCGCTTCGAGTACGACGACCCTCGCTTCCTCAGGCTGCTGGACCTAGCTCAGGAGGGACTGAAGGAGGAGTCGGGCTTTCTGCGCGAG
Seq C2 exon
GTGCTGAATGCTGTCCCCGTCCTCCTGCATATCCCAGCGCTGGCTGGCAAGGTCCTACGCTTCCAAAAGGCTTTCCTGACCCAGCTGGATGAGCTGCTAACTGAGCACAGGATGACCTGGGACCCAGCCCAGCCCCCCCGAGACCTGACTGAGGCCTTCCTGGCAGAGATGGAGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000100197-'3-5,'3-3,4-5=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.007 C2=0.149
Domain overlap (PFAM):
C1:
PF0006717=p450=FE(11.1=100)
A:
PF0006717=p450=PD(1.2=1.9),PF0006717=p450=FE(16.1=100)
C2:
PF0006717=p450=FE(17.6=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAAGAAGTCGCTGGAGCAGTG
R:
TCTCCATCTCTGCCAGGAAGG
Band lengths:
246-407
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains