Special

MmuEX0013342 @ mm9

Exon Skipping

Gene
ENSMUSG00000061740 | Cyp2d22
Description
cytochrome P450, family 2, subfamily d, polypeptide 22 [Source:MGI Symbol;Acc:MGI:1929474]
Coordinates
chr15:82202820-82204486:-
Coord C1 exon
chr15:82204334-82204486
Coord A exon
chr15:82203541-82203717
Coord C2 exon
chr15:82202820-82203007
Length
177 bp
Sequences
Splice sites
3' ss Seq
CTTCTCTACTGCTCACACAGTTC
3' ss Score
5.36
5' ss Seq
AAGGTGATT
5' ss Score
5.88
Exon sequences
Seq C1 exon
GTATAGTCCTAGCACGGTATGGGCCTGCCTGGCGTCAGCAGCGGCGCTTCTCTGTGTCTACCATGCACCACTTTGGCCTGGGCAAGAAGTCACTGGAGCAGTGGGTGACTGAGGAGGCCAGATGCCTCTGTGCCGCCTTCGCTGACCATACTG
Seq A exon
TTCCTGAATGTGTTCCCGATGCTCCTGCGCATCCCGGGGCTGGTTGGCAAGGTCTTCCCTGGGAAAAGGGCCTTTGTTACCATGTTGGATGAGCTGCTGGCTGAACACAAGACGACCTGGGACCCTACCCAGCCACCCCGAGATTTGACTGATGCCTTCCTGGCTGAGGTGGAGAAG
Seq C2 exon
GCCGAGTACAACAGGAAATCGATGAAGTCATAGGGCAGGTGCAGTGTCCAGAGATGGCAGACCAGGCTCGCATGCCCTACACCAATGCTGTCATTCATGAGGTGCAGCGCTTTGCAGACATTCTCCCTCTTGGTGTACCTCACAAGACTTCTCGTGACATTGAACTACAGGGCTTCCTTATCCCTAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000061740_MULTIEX1-2/3=C1-C2
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.085 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0006717=p450=FE(11.1=100)

							
A:
PF0006717=p450=FE(12.6=100)

							
C2:
PF0006717=p450=FE(13.4=100)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000023083





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000131100
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr22:42128174-42128350 
HIGH PSI
HsaEX6027102
(CYP2D6)
Human
(hg19)
chr22:42524176-42524352 
HIGH PSI
HsaEX6027102
(CYP2D6)
Rat
(rn6)
chr7:123600921-123601097 
Cow
(bosTau6)
chr5:113610793-113610969 
Chicken
(galGal4)
chr9:15159345-15159521 
GgaEX6046402
([1])
Chicken
(galGal3)
chr9:16789430-16789472 
GgaEX6046402
(E1C788_CHICK)
Zebrafish
(danRer10)
chr20:25692066-25692242 
HIGH PSI
DreEX0025452
(cyp2p10)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
TAGTCCTAGCACGGTATGGGC

				
R: 
GACAGCATTGGTGTAGGGCAT

				
Band lengths: 
242-419

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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