Special

MmuEX0014260 @ mm9

Exon Skipping

Gene
ENSMUSG00000027901 | Dennd2d
Description
DENN/MADD domain containing 2D [Source:MGI Symbol;Acc:MGI:2181193]
Coordinates
chr3:106295347-106297926:+
Coord C1 exon
chr3:106295347-106295495
Coord A exon
chr3:106296132-106296220
Coord C2 exon
chr3:106297749-106297926
Length
89 bp
Sequences
Splice sites
3' ss Seq
ATTTATTTATTTATTTATAGAAT
3' ss Score
6.95
5' ss Seq
CAGGTGCAG
5' ss Score
4.95
Exon sequences
Seq C1 exon
TTCATCTCACTGACACGGCCCCTAGACTCCCACCTTGAACACGTGGACTTCAGTGTTCTGCTACACTGTCTCCATTTGGAGCAGATTATTCAGATCTTTGCCTCTGCAGTGCTGGAAAGAAAAATCATCTTTTTGGCAGAGGGTCTCAG
Seq A exon
AATGGAAATGATGTGGACGGTGCCTTATAGGGTTGTGATGGGGACTAAAGGTGATAACGCACAGTGGTAGACATCCTGGACTCCAACAG
Seq C2 exon
TACCCTGTCTCAGTGTATCCATGCTGCTGCAGCTCTGCTTTACCCATTTAGTTGGGCACACACATACATCCCTGTGGTCCCTGAGAGCCTTCTGGCCACTGTCTGCTGCCCTACCCCCTTCATGGTTGGGGTACAGATGCGCTTCCTGCAGGAGGTTATGGACAGTCCCATGGAAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000027901-'11-10,'11-9,12-10
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0214116=DENN=FE(26.5=100)

							
A:
PF0214116=DENN=PD(5.6=29.2)

							
C2:
PF0214116=DENN=FE(31.9=100)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000053035f2201A





     
                   









    
Main Skipping Isoform:
ENSMUSP00000053035





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000029508
  



Associated events







Other assemblies


mm10




Conservation


Human
(hg38)
No conservation detected
Human
(hg19)
chr1:111736548-111736634 
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
chr3:32329547-32329633 
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
ACGTGGACTTCAGTGTTCTGC

				
R: 
CAGGGATGTATGTGTGTGCCC

				
Band lengths: 
183-272

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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