Special

MmuEX0025073 @ mm9

Exon Skipping

Gene
ENSMUSG00000043301 | Kcnj6
Description
potassium inwardly-rectifying channel, subfamily J, member 6 [Source:MGI Symbol;Acc:MGI:104781]
Coordinates
chr16:94984005-95162836:-
Coord C1 exon
chr16:95162788-95162836
Coord A exon
chr16:95053906-95054826
Coord C2 exon
chr16:94984005-94984292
Length
921 bp
Sequences
Splice sites
3' ss Seq
TCCCCCCTTCAAACTGACAGCTA
3' ss Score
5.46
5' ss Seq
CAGGTAAGA
5' ss Score
10.77
Exon sequences
Seq C1 exon
GAAAAGCACAAAGAAGAAATGACAATGGCCAAGTTAACTGAATCCATGA
Seq A exon
CTAACGTCTTGGAAGGCGATTCCATGGACCAGGATGTGGAAAGCCCAGTGGCCATTCACCAGCCAAAGTTGCCTAAGCAGGCCAGGGACGACCTGCCGAGACACATCAGCCGAGACAGGACCAAAAGGAAAATCCAGAGGTACGTGAGGAAGGATGGGAAGTGCAACGTTCACCACGGCAATGTGCGGGAGACGTACCGATACCTGACGGACATCTTCACCACCCTGGTGGACCTGAAGTGGAGATTCAACCTGTTGATCTTTGTCATGGTCTACACAGTGACGTGGCTTTTCTTTGGGATGATCTGGTGGCTGATTGCGTACATCCGGGGAGATATGGACCACATAGAGGACCCCTCGTGGACTCCTTGTGTCACCAACCTCAACGGGTTTGTCTCTGCTTTTTTATTCTCCATAGAGACAGAAACCACCATCGGTTATGGCTACCGGGTCATCACGGACAAGTGCCCTGAGGGGATTATTCTCCTCTTAATCCAGTCCGTGTTGGGGTCCATTGTCAACGCCTTCATGGTAGGATGTATGTTTGTGAAAATATCCCAACCCAAGAAGAGGGCAGAGACCCTGGTCTTTTCCACCCACGCGGTGATCTCCATGCGGGATGGGAAACTGTGCTTGATGTTCCGGGTGGGGGACTTGAGGAATTCTCACATTGTGGAGGCATCCATCAGAGCCAAGTTGATCAAGTCCAAACAGACTTCAGAGGGGGAGTTTATTCCCCTCAACCAGACTGATATCAACGTGGGGTACTACACAGGGGACGACCGGCTCTTTCTGGTGTCACCATTGATTATTAGCCATGAAATTAACCAACAGAGTCCCTTCTGGGAGATCTCCAAAGCGCAGCTGCCTAAAGAGGAACTGGAGATTGTGGTCATCCTGGAGGGAATGGTGGAAGCCACAG
Seq C2 exon
GAATGACGTGCCAAGCCCGAAGCTCCTACATCACCAGTGAGATCTTGTGGGGTTACCGGTTCACACCTGTCCTAACGCTGGAAGACGGGTTCTACGAAGTTGACTACAACAGCTTCCATGAGACCTATGAGACCAGCACCCCGTCCCTTAGTGCCAAAGAGCTAGCGGAGCTGGCTAACCGGGCAGAGCTGCCTCTGAGTTGGTCTGTGTCCAGCAAACTGAACCAACATGCAGAATTGGAGACAGAAGAGGAAGAGAAGAACCCGGAAGAACTGACGGAGAGGAATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000043301-'1-6,'1-3,5-6
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.008 C2=0.294
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
NO

							
A:
PF0100715=IRK=PU(76.4=84.1)

							
C2:
PF0100715=IRK=PD(23.3=81.4)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000097108





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000052888, ENSMUSP00000093558
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr21:37714211-37715131 
HIGH PSI
HsaEX6006139
(KCNJ6)
Human
(hg19)
chr21:39086514-39087434 
ALTERNATIVE
HsaEX6006139
(KCNJ6)
Rat
(rn6)
chr11:35097921-35098841 
Cow
(bosTau6)
chr1:151610074-151610994 
Chicken
(galGal4)
chr1:106629234-106630154 
Chicken
(galGal3)
chr1:110708740-110709660 
Zebrafish
(danRer10)
chr10:134508-135432 
HIGH PSI
DreEX0005301
(KCNJ6)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
GAAAAGCACAAAGAAGAAATGACAA

				
R: 
TCCTCTCCGTCAGTTCTTCCG

				
Band lengths: 
334-1255

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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