MmuEX0026873 @ mm10
Exon Skipping
Gene
ENSMUSG00000027070 | Lrp2
Description
low density lipoprotein receptor-related protein 2 [Source:MGI Symbol;Acc:MGI:95794]
Coordinates
chr2:69479099-69481414:-
Coord C1 exon
chr2:69481125-69481414
Coord A exon
chr2:69480016-69480219
Coord C2 exon
chr2:69479099-69479341
Length
204 bp
Sequences
Splice sites
3' ss Seq
TTTGCTTCTCTCTGTCCCAGGTC
3' ss Score
11.63
5' ss Seq
GTGGTGAGC
5' ss Score
6.64
Exon sequences
Seq C1 exon
GCAGAAAATAGAGCGCAGTACTCTCACGGGCTCCAACCGAGAAGTTGTCATCAGCACTGCCTTCCATTCCTTTGGCTTAACTGTCTACGGCCAGTACATTTACTGGACAGACTTTTACACCAAAAAAATCTACCGTGCTAACAAGTACGATGGGTCAGACCTGATTGCAATGACCACTCGTTTGCCCACCCAGCCTAGTGGCATCTCCACAGTTGTCAAGACCCAGCAGCAGCAGTGTAGCAATCCTTGTGACCAGTTCAATGGAGGATGCAGCCATATCTGTGCTCCAG
Seq A exon
GTCCAAACGGAGCTGAGTGCCAGTGTCCACACGAAGGCAGCTGGTATCTGGCCAACGATAACAAGTACTGTGTGGTGGACACAGGTGCCCGCTGTAATCAGTTCCAGTTCACCTGCCTTAATGGGCGTTGTATCTCTCAGGATTGGAAATGTGACAATGACAACGACTGTGGTGATGGCAGTGATGAGCTGCCCACAGTCTGTG
Seq C2 exon
CCTTTCACACGTGCCGATCAACAGCCTTCACTTGTGCCAATGGGCGATGTGTGCCATACCATTATCGCTGTGATTTCTACAATGACTGCGGGGACAACAGCGATGAGGCAGGATGCCTATTCAGGAGCTGCAACAGCACCACAGAGTTCACTTGCAGCAACGGGAGGTGTATACCTCTTAGTTATGTCTGCAATGGCATAAACAACTGCCATGACAATGACACCTCAGATGAGAAAAACTGCC
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000027070-'51-50,'51-48,53-50
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.010 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=PD(74.4=29.6),PF146701=FXa_inhibition=PU(36.8=14.3)
A:
PF146701=FXa_inhibition=PD(60.5=33.3),PF0005713=Ldl_recept_a=WD(100=56.5)
C2:
PF0005713=Ldl_recept_a=WD(100=45.1),PF0005713=Ldl_recept_a=WD(100=48.8)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGATGGGTCAGACCTGATTGC
R:
TGCTGCAAGTGAACTCTGTGG
Band lengths:
302-506
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types