MmuEX0026894 @ mm10
Exon Skipping
Gene
ENSMUSG00000024913 | Lrp5
Description
low density lipoprotein receptor-related protein 5 [Source:MGI Symbol;Acc:MGI:1278315]
Coordinates
chr19:3649404-3652330:-
Coord C1 exon
chr19:3652133-3652330
Coord A exon
chr19:3651843-3651955
Coord C2 exon
chr19:3649404-3649600
Length
113 bp
Sequences
Splice sites
3' ss Seq
TGATGGAACTGTTTCCACAGCAA
3' ss Score
5.21
5' ss Seq
GAGGTAGAG
5' ss Score
4.86
Exon sequences
Seq C1 exon
GTACATGTACTGGACTGACTGGGGGGAAGCACCCCGGATCGAGCGGGCAGGGATGGATGGCAGTACCCGGAAGATCATTGTAGACTCCGACATTTACTGGCCCAATGGGCTGACCATCGACCTGGAGGAACAGAAGCTGTACTGGGCCGATGCCAAGCTCAGCTTCATCCACCGTGCCAACCTGGACGGCTCCTTCCG
Seq A exon
CAATATGCTGAACGTTCCTTCCAAACTGTGTGAGAGGAACATACATAGCCTCCGAGATGGCAGCTGTGCAAGGCGGGCTCTGAGTTCAATCCCTGCAGGCCACACGATAAGAG
Seq C2 exon
GCAGAAGGTGGTGGAGGGCAGCCTCACTCACCCTTTTGCCCTGACACTCTCTGGGGACACACTCTACTGGACAGACTGGCAGACCCGCTCCATCCACGCCTGCAACAAGTGGACAGGGGAGCAGAGGAAGGAGATCCTTAGTGCTCTGTACTCACCCATGGACATCCAAGTGCTGAGCCAGGAGCGGCAGCCTCCCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000024913_CASSETTE6
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
In the CDS, with uncertain impact
Show structural model
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.036
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=WD(100=62.7),PF0005812=Ldl_recept_b=PU(56.4=32.8)
A:
PF0005812=Ldl_recept_b=PD(14.8=10.3)
C2:
PF0005812=Ldl_recept_b=PD(41.0=23.9)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATGTACTGGACTGACTGGGGG
R:
TGTGTCCCCAGAGAGTGTCAG
Band lengths:
255-368
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types