MmuEX0026894 @ mm9
Exon Skipping
Gene
ENSMUSG00000024913 | Lrp5
Description
low density lipoprotein receptor-related protein 5 [Source:MGI Symbol;Acc:MGI:1278315]
Coordinates
chr19:3649404-3652330:-
Coord C1 exon
chr19:3652133-3652330
Coord A exon
chr19:3651843-3651955
Coord C2 exon
chr19:3649404-3649600
Length
113 bp
Sequences
Splice sites
3' ss Seq
TGATGGAACTGTTTCCACAGCAA
3' ss Score
5.21
5' ss Seq
GAGGTAGAG
5' ss Score
4.86
Exon sequences
Seq C1 exon
GTACATGTACTGGACTGACTGGGGGGAAGCACCCCGGATCGAGCGGGCAGGGATGGATGGCAGTACCCGGAAGATCATTGTAGACTCCGACATTTACTGGCCCAATGGGCTGACCATCGACCTGGAGGAACAGAAGCTGTACTGGGCCGATGCCAAGCTCAGCTTCATCCACCGTGCCAACCTGGACGGCTCCTTCCG
Seq A exon
CAATATGCTGAACGTTCCTTCCAAACTGTGTGAGAGGAACATACATAGCCTCCGAGATGGCAGCTGTGCAAGGCGGGCTCTGAGTTCAATCCCTGCAGGCCACACGATAAGAG
Seq C2 exon
GCAGAAGGTGGTGGAGGGCAGCCTCACTCACCCTTTTGCCCTGACACTCTCTGGGGACACACTCTACTGGACAGACTGGCAGACCCGCTCCATCCACGCCTGCAACAAGTGGACAGGGGAGCAGAGGAAGGAGATCCTTAGTGCTCTGTACTCACCCATGGACATCCAAGTGCTGAGCCAGGAGCGGCAGCCTCCCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000024913_CASSETTE4
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
In the CDS, with uncertain impact
Show structural model
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.027
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=WD(100=62.7),PF0005812=Ldl_recept_b=PU(56.4=32.8)
A:
PF0005812=Ldl_recept_b=PD(14.8=10.3)
C2:
PF0005812=Ldl_recept_b=PD(41.0=23.9),PF0005812=Ldl_recept_b=WD(100=55.2)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Human
(hg38)
No conservation detected
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATGTACTGGACTGACTGGGGG
R:
TGTGTCCCCAGAGAGTGTCAG
Band lengths:
255-368
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types