Special

MmuEX0027253 @ mm9

Exon Skipping

Gene
ENSMUSG00000002020 | Ltbp2
Description
latent transforming growth factor beta binding protein 2 [Source:MGI Symbol;Acc:MGI:99502]
Coordinates
chr12:86135991-86145435:-
Coord C1 exon
chr12:86145307-86145435
Coord A exon
chr12:86140322-86140441
Coord C2 exon
chr12:86135991-86136110
Length
120 bp
Sequences
Splice sites
3' ss Seq
TCCTATCTATGTGTTTGCAGATA
3' ss Score
10.24
5' ss Seq
AAGGTAAGG
5' ss Score
10.51
Exon sequences
Seq C1 exon
ACTTTGATCCATGTTTTGCTGGAGCCTCCAACATCTGTGGCCCTGGGACCTGTGTGAGCCTCCCAAATGGATACAGATGTGTCTGCAGCCCTGGCTACCAGCTACACCCCAGCCAAGACTACTGTACTG
Seq A exon
ATATCGATGAGTGTGAGCAGCCCGGGGTGTGCAGTGGTGGGCGATGCAGCAACACGGAGGGCTCGTACCACTGCGAGTGTGATCGGGGCTACATCATGGTCAGGAAAGGACACTGTCAAG
Seq C2 exon
ATATCAACGAATGCCGTCACCCTGGTACCTGCCCTGATGGGAGATGCGTCAACTCCCCTGGCTCCTACACTTGTCTGGCCTGTGAGGAGGGCTATGTAGGCCAGAGTGGGAGCTGTGTAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000002020-'19-20,'19-17,21-20=AN
Average complexity
A_C2
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF062476=Plasmod_Pvs28=PU(28.8=81.8),PF146701=FXa_inhibition=WD(100=79.5),PF0764510=EGF_CA=PU(0.1=0.0)

							
A:
PF062476=Plasmod_Pvs28=FE(32.0=100),PF0764510=EGF_CA=WD(100=95.1),PF0764510=EGF_CA=PU(0.1=0.0)

							
C2:
PF062476=Plasmod_Pvs28=FE(32.0=100),PF0764510=EGF_CA=WD(100=95.1),PF0764510=EGF_CA=PU(0.1=0.0)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000105883





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000002073, ENSMUSP00000127693, ENSMUSP00000128882, ENSMUSP00000128882f99A, ENSMUSP00000132690
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr14:74516822-74516941 
HIGH PSI
HsaEX0036904
(LTBP2)
Human
(hg19)
chr14:74983525-74983644 
HIGH PSI
HsaEX0036904
(LTBP2)
Rat
(rn6)
chr6:108519861-108519980 
HIGH PSI
RnoEX6029360
(Ltbp2)
Cow
(bosTau6)
chr10:86204520-86204639 
HIGH PSI
BtaEX6055043
(LTBP2)
Chicken
(galGal4)
chr5:37222229-37222348 
HIGH PSI
GgaEX1034364
(LTBP2)
Chicken
(galGal3)
chr5:40351025-40351144 
HIGH PSI
GgaEX1034364
(LTBP2)
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
TCCATGTTTTGCTGGAGCCTC

				
R: 
CTACACAGCTCCCACTCTGGC

				
Band lengths: 
242-362

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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