Special

MmuEX0027260 @ mm10

Exon Skipping

Gene
ENSMUSG00000002020 | Ltbp2
Description
latent transforming growth factor beta binding protein 2 [Source:MGI Symbol;Acc:MGI:99502]
Coordinates
chr12:84790242-84791722:-
Coord C1 exon
chr12:84791597-84791722
Coord A exon
chr12:84790995-84791117
Coord C2 exon
chr12:84790242-84790373
Length
123 bp
Sequences
Splice sites
3' ss Seq
CATGGGCATCTCTATCCTAGATG
3' ss Score
7.86
5' ss Seq
TGGGTAAGG
5' ss Score
9.08
Exon sequences
Seq C1 exon
ACGTGAATGAGTGTGTTGGGGAAGAGCATTGTGCTCCTCACGGCGAGTGCCTCAACAGCCTGGGCTCCTTCTTCTGCCTCTGTGCACCCGGCTTTGCTAGTGCTGAGGGGGGCACCAGATGCCAGG
Seq A exon
ATGTTGATGAATGTGCAGCCACAGACCCGTGTCCGGGAGGACACTGTGTCAACACAGAGGGCTCCTTCAGCTGTCTGTGTGAGACTGGCTTCCAGCCCTCCCCAGACAGCGGAGAATGTTTGG
Seq C2 exon
ATATTGATGAGTGTGAGGACCGTGAAGACCCGGTGTGCGGAGCCTGGAGGTGTGAGAACAGTCCTGGTTCCTACCGCTGCATCCTGGACTGCCAGCCTGGCTTCTATGTGGCGCCAAATGGAGACTGCATTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000002020-'41-41,'41-40,43-41
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0764510=EGF_CA=WD(100=95.3),PF0764510=EGF_CA=PU(0.1=0.0)

							
A:
PF0764510=EGF_CA=WD(100=95.2),PF0764510=EGF_CA=PU(0.1=0.0)

							
C2:
PF0764510=EGF_CA=WD(100=95.6),PF0764510=EGF_CA=PU(0.1=0.0)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000002073





     
                   









    
Main Skipping Isoform:
ENSMUST00000002073fB12382





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000105883, ENSMUSP00000127693
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm9




Conservation


Human
(hg38)
chr14:74507973-74508095 
HIGH PSI
HsaEX0036911
(LTBP2)
Human
(hg19)
chr14:74974676-74974798 
HIGH PSI
HsaEX0036911
(LTBP2)
Rat
(rn6)
chr6:108511842-108511964 
HIGH PSI
RnoEX6029363
(Ltbp2)
Cow
(bosTau6)
chr10:86195463-86195585 
HIGH PSI
BtaEX6055050
(LTBP2)
Chicken
(galGal4)
chr5:37218409-37218531 
HIGH PSI
GgaEX1034376
(LTBP2)
Chicken
(galGal3)
chr5:40346486-40346608 
HIGH PSI
GgaEX1034376
(LTBP2)
Zebrafish
(danRer10)
chr18:49026105-49026179 
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
ACGTGAATGAGTGTGTTGGGG

				
R: 
GTCTCCATTTGGCGCCACATA

				
Band lengths: 
251-374

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types





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