MmuEX0027261 @ mm10

Exon Skipping

Gene

ENSMUSG00000002020 | Ltbp2

Description

latent transforming growth factor beta binding protein 2 [Source:MGI Symbol;Acc:MGI:99502]

Coordinates

chr12:84789084-84791944:-

Coord C1 exon

chr12:84791822-84791944

Coord A exon

chr12:84790242-84790373

Coord C2 exon

chr12:84789084-84789227

Length

132 bp

Sequences

Splice sites

3' ss Seq

TCTCATGGCTCTGGGGACAGATA

3' ss Score

4.66

5' ss Seq

TTGGTGAGT

5' ss Score

9.27

Exon sequences

Seq C1 exon

ATGTGGATGAGTGTGAAGGTCCCCAAAGCAGCTGCCGGGGAGGCGAATGCAAGAACACAGAAGGTTCCTACCAATGCCTCTGTCACCAGGGCTTCCAGCTGGTCAATGGCACCATGTGTGAGG

Seq A exon

ATATTGATGAGTGTGAGGACCGTGAAGACCCGGTGTGCGGAGCCTGGAGGTGTGAGAACAGTCCTGGTTCCTACCGCTGCATCCTGGACTGCCAGCCTGGCTTCTATGTGGCGCCAAATGGAGACTGCATTG

Seq C2 exon

ATGTGAACGAGTGTGAGCTCATGATGGCAGTGTGTGGGGATGCGCTCTGTGAGAACGTGGAAGGCTCCTTCCTGTGCCTTTGCGCCAGTGACCTTGAGGAGTACGACGCAGAAGAAGGACACTGCCGTCCTCGGGTGGCTGGAG

VastDB Features

Vast-tools module Information

Secondary ID

ENSMUSG00000002020_MULTIEX2-3/10=C1-5

Average complexity

C3

Mappability confidence:

100%=100=100%

Protein Impact

Alternative protein isoforms (Ref)

No structure available

Features

Disorder rate (Iupred):

C1=0.000 A=0.000 C2=0.000

Domain overlap (PFAM):

C1:

PF0764510=EGF_CA=WD(100=95.2),PF0764510=EGF_CA=PU(0.1=0.0)

A:

PF0764510=EGF_CA=WD(100=95.6),PF0764510=EGF_CA=PU(0.1=0.0)

C2:

PF0764510=EGF_CA=WD(100=85.7)

Main Inclusion Isoform:

ENSMUSP00000002073

Main Skipping Isoform:

ENSMUST00000002073fB12382

Other Inclusion Isoforms:

ENSMUSP00000105883, ENSMUSP00000127693, ENSMUSP00000132067

Other Skipping Isoforms:

NA

Associated events

Other assemblies

mm9

Conservation

Human

(hg38)

chr14:74507179-74507310

HIGH PSI

HsaEX0036912

(LTBP2)

Human

(hg19)

chr14:74973882-74974013

HIGH PSI

HsaEX0036912

(LTBP2)

Rat

(rn6)

chr6:108507257-108507388

ALTERNATIVE

RnoEX0051381

(Ltbp2)

Cow

(bosTau6)

chr10:86194692-86194823

HIGH PSI

BtaEX6055051

(LTBP2)

Chicken

(galGal4)

chr5:37218109-37218240

HIGH PSI

GgaEX1034366

(LTBP2)

Chicken

(galGal3)

chr5:40346186-40346317

HIGH PSI

GgaEX1034366

(LTBP2)

Zebrafish

(danRer10)

chr18:49025162-49025289

Fruitfly

(dm6)

No conservation detected

Primers PCR

Suggestions for RT-PCR validation

F:

GAGTGTGAAGGTCCCCAAAGC

R:

GACGGCAGTGTCCTTCTTCTG

Band lengths:

244-376

Functional annotations

(Submit an annotation)

There are 0 annotated functions for this event

GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]

SPECIAL DATASETS

Pre-implantation embryo development
Ribosome-engaged transcriptomes of neuronal types
Neural differentiation time course
Muscular differentiation time course
Spermatogenesis cell types
Reprogramming of fibroblasts to iPSCs
Hematopoietic precursors and cell types

Special

MmuEX0027261 @ mm10

GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]

SPECIAL DATASETS