MmuEX0033134 @ mm10
Exon Skipping
Gene
ENSMUSG00000043964 | Orai3
Description
ORAI calcium release-activated calcium modulator 3 [Source:MGI Symbol;Acc:MGI:3039586]
Coordinates
chr7:127769815-127775150:+
Coord C1 exon
chr7:127769815-127770216
Coord A exon
chr7:127770734-127770878
Coord C2 exon
chr7:127773557-127775150
Length
145 bp
Sequences
Splice sites
3' ss Seq
ATGTCAGCTAACGGTCCCAGCAG
3' ss Score
-1.42
5' ss Seq
AAGGTGCTG
5' ss Score
4.05
Exon sequences
Seq C1 exon
CCAGTTCCTGTTTCGGCCCCTGGGCCTTCTAGACGCGTCCGTAACTGTTCCCGCTGGGTCTGCCTTGCCACCCAGGATGGGGTCCCACCCGCGCTTGGGCCGTCCCTTCTTGGGGATACAAGGCGCCTCGGCCCCTCCTTGACCATCTGCGCTTGTGGTGTAACTGCTCTCAGGATGAAGGGCGGCGAGGGGGACACGGGCGAACAGGCCCCGCTGAACCCGGAGGTGGACAGCCCCGCGGGCTCAGCCACGTACCGGGAGTTCGTGCACCGCGGCTACCTGGACCTTATGGGGGCCAGTCAGCACTCTCTGCGGGCGCTCAGCTGGCGCCGCCTCTACCTCAGCCGGGCTAAGCTCAAAGCCTCCAGCCGCACATCTGCTCTGCTGTCGGGCTTCGCCATG
Seq A exon
CAGTGGCCCCGGGAAGTGGAACTGAAGATTCCAGAGTGTGGCCTGCAGATGTGTCCTGGTTCCTCCCTACTTAGGGCCAGCTGTGCGGCCCCAAGTCGACATCCACTCCAGTTGCCATCTTTAGGAAGTTGTGACATCATAGAAG
Seq C2 exon
GTGGCCATGGTGGAGGTACAGCTGGAGAACGATCATGAATACCCACCAGGCCTGCTGGTGGCATTTAGTGCCTGCACCACTGTGTTAGTAGCTGTGCACCTCTTTGCACTGATGGTCTCCACATGTCTGCTGCCCCATATTGAAGCCGTGAGCAACATCCACAATCTCAACTCTGTCCACCAGTCACCACACCAACGACTGCACAGATACGTGGAGCTTGCCTGGGGCTTCTCTACTGCCTTGGGTACCTTTCTCTTCCTGGCTGAAGTTGTTCTGGTGGGCTGGGTCAAGTTTGTGCCCATTGGGGCACCCATGGGTAAACCAGCTCCTGTTGTACCTATGTCCCAGGTGCCACCTGTGACTGTCTCCCTTAGTTTAGCTTCTAACCTCACACCATCCTCTGCTTCTATTACCACATCACAACAGCCTTCCAAAGCCTGTCCACCCCGGCAAGTGTGTGATAGTGCTCATGGACCAGGCTGGCAGGCAGCTATGGCCTC
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000043964_CASSETTE1
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.254 A=0.000 C2=0.126
Domain overlap (PFAM):
C1:
PF078567=Orai-1=PU(14.6=44.7)
A:
PF078567=Orai-1=PD(32.1=34.7)
C2:
PF078567=Orai-1=PD(84.5=91.6),PF105414=KASH=WD(100=24.2)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTACCTGGACCTTATGGGGGC
R:
ACCATCAGTGCAAAGAGGTGC
Band lengths:
243-388
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types