Special

MmuEX0034057 @ mm9

Exon Skipping

Gene
ENSMUSG00000004630 | Pcp2
Description
Purkinje cell protein 2 (L7) [Source:MGI Symbol;Acc:MGI:97508]
Coordinates
chr8:3623371-3624632:-
Coord C1 exon
chr8:3624508-3624632
Coord A exon
chr8:3623696-3623754
Coord C2 exon
chr8:3623371-3623558
Length
59 bp
Sequences
Splice sites
3' ss Seq
TGTTTGTTTGTTTGTTTTAGTAT
3' ss Score
9.53
5' ss Seq
CAGGTATAC
5' ss Score
7.48
Exon sequences
Seq C1 exon
AGGGTGGCCCTGCTCCAGAGATGGACAATCTCATGGATATGCTGGTCAACACCCAGGGCCGCCGCATGGACGACCAGCGTGTAACAGTTAATTCCCTGCCTGGCTTCCAACCTATCGGCCCCAAG
Seq A exon
TATTTAGCTTTGAACTCAAAATAATCCTCCTGCCTGTTTCTTGAGTACTGGGATTACAG
Seq C2 exon
GATGGAATGCAGAAACGACCTGGGACCCTCAGCCCTCAACCCCTGCTCACCCCTCAGGATCCTGCTGCACTCAGCTTCCGCAGGAACAGCAGCCCCCAGCCCCAGACACAAGCTCCTTGAGAGTTCTAGCCATCCTGGGCCTCCCACTGGCCCCTGAAAACAATAAAACACTTGGCACTAGCAACAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000004630_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence inclusion (Alt. Stop)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.997 A=0.714 C2=1.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0218812=GoLoco=WD(100=54.8)

							
A:
NO

							
C2:
NO

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000121079f202A





     
                   









    
Main Skipping Isoform:
ENSMUSP00000121079





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000004749, ENSMUSP00000121403, ENSMUSP00000122902
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
CCCTGCTCCAGAGATGGACAA

				
R: 
GTCCCAGGTCGTTTCTGCATT

				
Band lengths: 
144-203

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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