Special

MmuEX0043381 @ mm9

Exon Skipping

Gene
ENSMUSG00000026904 | Slc4a10
Description
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10 [Source:MGI Symbol;Acc:MGI:2150150]
Coordinates
chr2:62102010-62105632:+
Coord C1 exon
chr2:62102010-62102110
Coord A exon
chr2:62103099-62103236
Coord C2 exon
chr2:62105458-62105632
Length
138 bp
Sequences
Splice sites
3' ss Seq
TGCTTCCTAAATCCTCCCAGGTC
3' ss Score
7.35
5' ss Seq
TCTGTAATG
5' ss Score
-4.32
Exon sequences
Seq C1 exon
GAGAAGAGGAAGATTCCTGCTGTACCAAATGGAACAGCAGCTCATGGCGAAGCTGAGCCACATGGAGGACACAGCGGACCTGAACTCCAGCGAACTGGGAG
Seq A exon
GTCACCAATATCCGGTATCTTCGCTTCTCCAGAGTTCTTCCACAGACTCTGTGGCTGACATGACTTGAAGTTTCCATTACTCATCTGCTCTCCTGGAATTGCTGGTGTACATCTGGGCTGCTCTTGCACTGTTCTTCT
Seq C2 exon
GATTTTTGGGGGACTTATATTAGATATCAAAAGAAAGGCTCCATTCTTCTGGAGTGACTTCAGGGATGCTTTCAGCCTGCAGTGCTTAGCATCGTTCCTGTTTCTCTACTGTGCATGCATGTCTCCTGTCATCACATTTGGAGGACTGTTGGGAGAAGCAACTGAAGGTCGTATA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026904_CASSETTE2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.877 A=0.158 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0095516=HCO3_cotransp=PU(1.2=17.6)

							
A:
NO

							
C2:
PF0095516=HCO3_cotransp=FE(11.3=100)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000108099f2024A





     
                   









    
Main Skipping Isoform:
ENSMUSP00000108099





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000061411, ENSMUSP00000099796
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr2:161902028-161902164 
ALTERNATIVE
HsaEX0059783
(SLC4A10)
Human
(hg19)
chr2:162758538-162758674 
ALTERNATIVE
HsaEX0059783
(SLC4A10)
Rat
(rn6)
chr3:48218295-48218432 
LOW PSI
RnoEX0082784
(Slc4a10)
Cow
(bosTau6)
chr2:34680301-34680437 
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
TCCTGCTGTACCAAATGGAACA

				
R: 
CGACCTTCAGTTGCTTCTCCC

				
Band lengths: 
258-396

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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