Special

MmuEX0047321 @ mm9

Exon Skipping

Gene
ENSMUSG00000023800 | Tiam2
Description
T cell lymphoma invasion and metastasis 2 [Source:MGI Symbol;Acc:MGI:1344338]
Coordinates
chr17:3477175-3503060:+
Coord C1 exon
chr17:3477175-3477278
Coord A exon
chr17:3486649-3486848
Coord C2 exon
chr17:3502881-3503060
Length
200 bp
Sequences
Splice sites
3' ss Seq
ACTCTGAGTCCTGCTTGCAGGTT
3' ss Score
6.41
5' ss Seq
CATGTAAGA
5' ss Score
5.58
Exon sequences
Seq C1 exon
ATTTCAGCAATGTCCCTGAGATCACAACTGGCTTGAAGAGGAGCCAGACAGAAGGCACCCTGGATCAAGTGCCCCACAGGGAAAAGATGGAGCAGACATTCCTG
Seq A exon
GTTCTTGAGCCTTCTTGTGGAGACTGGACCCATGGCCTGGGCTGATGATGGCTTCCTTTGTCCTTGGCTAAGCCACCAGACATCTGCATCTGTCTGAGAGGCAGCCCTGAGCTGACACATCTCCCTGCTCATCCTTCCGTCCAAATGTGTCACCTTGGGCAGTCCTTTACCTGACACTGCTGCTGCTCATCCTCATGCAT
Seq C2 exon
AGCGCTGACCAGATTGCGGAGCTCTGCAGGGACTTGAACAACACCCACACCAACAGTATGGAAGCACCAACAGAGAGCCATGACCCACCTCCCAGGCCTCTGGCTCGTCACCTCTCAGATGCAGATCGCCTCCGGAAAGTCATCCAGGAGCTTGTAGACACAGAGAAGTCTTACGTGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000023800-'19-21,'19-20,21-21
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.771 A=0.071 C2=0.489
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
NO

							
A:
NO

							
C2:
PF0062115=RhoGEF=PU(6.8=21.7)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000072020f1423A





     
                   









    
Main Skipping Isoform:
ENSMUSP00000072020





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000125842
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
No conservation detected
Human
(hg19)
chr6:155543058-155543975 
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
chr9:93203826-93204066 
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
ATTTCAGCAATGTCCCTGAGATCA

				
R: 
CTTCACGTAAGACTTCTCTGTGTCT

				
Band lengths: 
284-484

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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